130 patents
Page 2 of 7
Utility
Methods of Treating Solid Tumors with CCR2 Antagonists
4 Aug 22
James J. CAMPBELL, Rajinder SINGH, Samuel HWANG, Xuesong WU
Filed: 22 Sep 21
Utility
Capsule Formulations
28 Jul 22
Manmohan Reddy LELETI, Jay P. POWERS
Filed: 8 Dec 21
Utility
Method of Treating Focal Segmental Glomerulosclerosis
21 Jul 22
A method of treating focal segmental glomerulosclerosis with a compound of Formula I is provided.
Zhenhua MIAO, Thomas SCHALL, Rajinder SINGH
Filed: 8 Apr 22
Utility
Treatment of focal segmental glomerulosclerosis with CCR2 antagonists
12 Jul 22
Zhenhua Miao, Thomas J. Schall, Rajinder Singh
Filed: 11 Aug 20
Utility
6-5 fused rings as C5a inhibitors
12 Jul 22
Pingchen Fan, Christopher W. Lange, Rebecca M. Lui, Viengkham Malathong, Venkat Reddy Mali, Sreenivas Punna, Rajinder Singh, Hiroko Tanaka, Yibin Zeng, Penglie Zhang
Filed: 20 Dec 19
Utility
Substituted Anilines As CCR(4) Antagonists
23 Jun 22
Aniline compounds are provided which bind to CCR(4) and are useful for the treatment of diseases such as allergic diseases, autoimmune diseases, graft rejection and cancer.
Trevor T. CHARVAT, Junfa FAN, Christopher W. LANGE, Manmohan Reddy LELETI, Yandong LI, Venkat Reddy MALI, Jeffrey P. McMAHON, Jay POWERS, Sreenivas PUNNA, Ju YANG
Filed: 9 Sep 21
Utility
Method of treating liver fibrosis
14 Jun 22
A method of treating liver fibrosis with CCR2 antagonists is provided.
Zhenhua Miao, Israel Charo
Filed: 6 May 20
Utility
Indane-amines As PD-L1 Antagonists
9 Jun 22
Christopher LANGE, Sreenivas PUNNA, Rajinder SINGH, Ju YANG, Penglie ZHANG
Filed: 30 Aug 21
Utility
Method of Treating Focal Segmental Glomerulosclerosis
10 May 22
A method of treating focal segmental glomerulosclerosis with a compound of Formula I is provided.
Zhenhua Miao, Thomas Schall, Rajinder Singh
Filed: 19 Jun 20
Utility
Methods of Treating Hidradenitis Suppurativa
28 Apr 22
Shijie LI, Rajinder Singh, Thomas J. Schall, Peter Staehr
Filed: 27 Oct 21
Utility
CXCR7 Antagonists
28 Apr 22
Junfa FAN, Antoni KRASINSKI, Christopher W. LANGE, Rebecca M. LUI, Jeffrey P. McMAHON, Jay P. POWERS, Yibin ZENG, Penglie ZHANG
Filed: 27 May 21
Utility
Macrocyclic Immunomodulators
21 Apr 22
Viengkham MALATHONG, Jeffrey McMAHON, Darren J. McMURTRIE, Sreenivas PUNNA, Howard S. ROTH, Rajinder SINGH, Penglie ZHANG
Filed: 3 Jun 21
Utility
Combination therapy using a chemokine receptor 2 (CCR2) antagonist and a PD-1/PD-L1 inhibitor
19 Apr 22
The present disclosure is drawn to the combination therapy of a Chemokine Receptor 2 (CCR2) antagonist and a PD-1 and/or PD-L1 inhibitor in the treatment of cancer.
James J. Campbell, Zhenhua Miao, Thomas J. Schall, Israel Charo, Shijie Li, Christine Marie Janson, Rajinder Singh, Karen Ebsworth
Filed: 24 Sep 18
Utility
FREE BASE CRYSTALLINE FORM OF A COMPLEMENT COMPONENT C5a RECEPTOR
31 Mar 22
Rajinder SINGH, Kwok YAU, Yibin ZENG, Penglie ZHANG, Rebecca M. LUI, Antoni KRASINSKI
Filed: 4 May 21
Utility
Method of treating C3 glomerulopathy
29 Mar 22
Methods of treating a human suffering from or susceptible to C3 glomerulopathy comprising administering to the human an effective amount of a C5aR antagonist are provided.
Petrus Bekker
Filed: 8 Nov 18
Utility
Triaryl compounds for treatment of PD-L1 diseases
8 Mar 22
Pingchen Fan, Christopher Lange, Venkat Reddy Mali, Darren J. McMurtrie, Viengkham Malathong, Sreenivas Punna, Rajinder Singh, Ju Yang, Yibin Zeng, Penglie Zhang
Filed: 14 May 20
Utility
Soluble C5aR antagonists
22 Feb 22
Pingchen Fan, Antoni Krasinski, Venkat Reddy Mali, Shichang Miao, Sreenivas Punna, Yang Song, Valentino J. Stella, Yibin Zeng, Penglie Zhang
Filed: 23 Oct 19
Utility
Aza-aryl 1H-PYRAZOL-1-YL Benzene Sulfonamides
17 Feb 22
Compounds are provided that act as potent antagonists of the CCR(9) receptor.
Xi CHEN, Junfa FAN, Pingchen FAN, Antoni KRASINSKI, Lianfa LI, Rebecca M. LUI, Jeffrey P. McMAHON, Jay P. POWERS, Yibin ZENG, Penglie ZHANG
Filed: 29 Oct 21
Utility
METHODS OF TREATING RESPIRATORY DISEASES USING C5a INHIBITORS
17 Feb 22
Provided herein are methods of treating a respiratory disease in a subject in need thereof by administering an effective amount of a small molecule C5a inhibitor.
Markus J. CAPPEL
Filed: 12 Aug 21
Utility
Inhibitors of CXCR2
13 Jan 22
Xi CHEN, Dean R. DRAGOLI, Junfa FAN, Jaroslaw KALISIAK, Manmohan Reddy LELETI, Viengkham MALATHONG, Jeffrey McMAHON, Hiroko TANAKA, Ju YANG, Chao YU, Penglie ZHANG, Venkat MALI
Filed: 29 Apr 21