34 patents
Page 2 of 2
Utility
Multiple Laminar Flow-based Particle and Cellular Separation with Laser Steering
16 Dec 21
The invention provides a method, apparatus and system for separating blood and other types of cellular components, and can be combined with holographic optical trapping manipulation or other forms of optical tweezing.
Daniel Mueth, Joseph Plewa, Jessica Shireman, Amy Anderson, Lewis Gruber, Neil Rosenbaum
Filed: 26 Aug 21
Utility
Bos Taurus Cell Type 'HO840003210132823'
2 Dec 21
The disclosure relates to Bovine germplasm of Bos taurus HO840003210132823.
Katrina Dattilo, Devan Funk
Filed: 18 May 21
Utility
c5b41ds gxlgi9r69apfefpl
2 Dec 21
A microfluidic chip orients and isolates components in a sample fluid mixture by two step focusing, where sheath fluids compress the sample fluid mixture in a sample input channel in one direction, such that the sample fluid mixture becomes a narrower stream bounded by the sheath fluids, and by having the sheath fluids compress the sample fluid mixture in a second direction further downstream, such that the components are compressed and oriented in a selected direction to pass through an interrogation chamber in single file formation for identification and separation by various methods.
Zheng Xia, Yu Zhou, John Larsen, Guocheng Shao, Shane Peterson, Marjorie Faust
Filed: 16 Aug 21
Utility
ldcbskcooc 8w48b76mhc6hc61hl4ypqyb16k2zo
15 Jul 21
Microfluidic devices and methods for focusing components in a fluid sample are described herein.
Zheng Xia, Gopakumar Kamalakshakurup
Filed: 13 Jan 20
Utility
rq1s2qotw8te9n93fn6tcov9bn247y
1 Apr 21
A cytometer includes an avalanche photodiode, a switching power supply, a filter, and voltage adjustment circuitry.
Frederick Savage, Glenn J. Szejna, Zheng Xia
Filed: 20 Nov 20
Utility
i3r3wf4z5dw2eogmwj ghsip04p1b4ljio5e7nix3wgxpe9cc3rkrph
16 Dec 20
The disclosure relates to Bovine germplasm of Bos taurus variety JE840003146074527.
Aaron Horst, Katrina Dattilo, Devan Funk
Filed: 16 Jun 19
Utility
vbg04up5k1n62anhrhowlg
2 Dec 20
A method of choosing which undesired cell to destroy in a multi-cell fluorescent event includes detecting fluorescence of cells, converting photons detected in the fluorescence into an analog voltage output signal, and identifying at least two discernable peaks associated with the cells.
Frederick Savage, Matthew Ebersole, Daniel McAda, David Appleyard, Zheng Xia
Filed: 28 May 20
Utility
6mw5quaw39r8jkaz76bpsh6zozvt41bhr6fy2qiw41aq
21 Oct 20
An integrated system and method for preparing sperm cells to improve their survivability during cryopreservation are described herein.
Domenic Busa, Michael Botts, Gary Klas, Johnathan Parker
Filed: 16 Apr 20
Utility
fora1hf47i1 oh3sdkg6s
30 Sep 20
The disclosure relates to Bovine germplasm of Bos taurus variety HO840M003150607238.
Devan Charles FUNK, Katrina Dattilo
Filed: 25 Mar 19
Utility
y6wle4uyr fombr3sg0k1m
8 Jul 20
A cytometer includes an avalanche photodiode, a switching power supply, a filter, and voltage adjustment circuitry.
Frederick Savage, Glenn J. Szejna, Zheng Xia
Filed: 17 Mar 20
Utility
9g98onby6a 4a1gg6eqd81lhn04s
11 Mar 20
A microfluidic chip orients and isolates components in a sample fluid mixture by two-step focusing, where sheath fluids compress the sample fluid mixture in a sample input channel in one direction, such that the sample fluid mixture becomes a narrower stream bounded by the sheath fluids, and by having the sheath fluids compress the sample fluid mixture in a second direction further downstream, such that the components are compressed and oriented in a selected direction to pass through an interrogation chamber in single file formation for identification and separation by various methods.
Zheng Xia, Yu Zhou, John Larsen, Guocheng Shao, Shane Peterson, Marjorie Faust
Filed: 8 Oct 19
Utility
uvl3ea5psv9c1sordw7rt6kgxwbzh9jum
25 Dec 19
The present invention provides novel methods of cell staining, such as bovine sperm, using electroporation or osmolality treatments at viability-enhancing temperatures.
Amy L. Morjal, Christopher R. Knutson, Daniel Mueth, Joseph Plewa, Evan Tanner
Filed: 4 Sep 19
Utility
nfagiy6d bq7y4ncv13szny9
18 Dec 19
A method and related apparatus for confirming whether a kill laser successfully destroys an undesired population of cells includes introducing fluorescent dye into cells, exciting the cells with a detection laser or a light emitting diode to cause the cell to fluoresce for a first time, measuring the amount of fluorescence in the cells with a detector capable of emitting a detection pulse, classifying the cells via embedded processing as undesired or desired cells based on the amount of fluorescence, firing a kill beam with a kill laser at any undesired cells, measuring the amount of fluorescence in the cells a second time to determine whether a fluorescent event was generated from the kill beam striking the cells, and providing feedback to an operator of the kill laser as to whether any fluorescent events were generated from the kill beam striking the cells.
Frederick Hershel Savage, David Appleyard, Zheng Xia, Matthew Ebersole, Daniel McAda
Filed: 13 Jun 19
Utility
xyo9kiu56f69yg8r6e8399 xtv3b4l7zg47y2btu25ajcc5x23tivwbn2eq7
27 Nov 19
A microfluidic system configured to focus particles suspended in a fluid.
Gerson Aguirre, Zheng Xia, Gopakumar Kamalakshakurup
Filed: 21 May 19