40 patents
Utility
Quinazolines, Pharmaceutical Compositions, and Therapeutic Applications
21 Sep 23
Paul E. Erdman, Leah M. Fung, Patrick Papa, Brandon Whitefield
Filed: 15 Mar 23
Utility
PDE4 Inhibitors, Pharmaceutical Compositions, and Therapeutic Applications
9 Mar 23
Kyle W.H. Chan, Paul E. Erdman, Leah M. Fung, David Aaron Hecht, Frank Mercurio, Robert W. Sullivan
Filed: 14 Dec 20
Utility
Pyrazolylpyrimidines and Use Thereof
16 Feb 23
Kyle W.H. Chan, Robert W. Sullivan
Filed: 12 Jan 21
Utility
Ras Protein Degraders, Pharmaceutical Compositions Thereof, and Their Therapeutic Applications
5 Jan 23
Kyle W.H. Chan, Aparajita Hoskote Chourasia, Paul E. Erdman, Leah M. Fung, David Aaron Hecht, Imelda Lam, Frank Mercurio, Robert W. Sullivan, Eduardo Torres
Filed: 14 Sep 20
Utility
Protein-targeting Compounds and Pharmaceutical Compositions Thereof, and Their Therapeutic Applications
22 Sep 22
Kyle W.H. Chan, Paul E. Erdman, Aparajita Hoskote Chourasia, Leah M. Fung, David Aaron Hecht, Imelda Lam, Frank Mercurio, Robert W. Sullivan, Eduardo Torres
Filed: 30 May 22
Utility
Pharmaceutical compositions comprising one or more pyrone compounds, and their use for treating inflammatory and neurodegenerative diseases
6 Sep 22
Armen Manoukian, Fabrizio Mastronardi, Sam Scanga, Frank Mercurio, Kyle W. H. Chan
Filed: 7 Oct 16
Utility
Aminoamide compounds
2 Aug 22
Compounds with amino amide linkers and pharmaceutical compositions and medicaments comprising such compounds are disclosed.
Kyle W. H. Chan, Aparajita Hoskote Chourasia, Paul E. Erdman, Leah M. Fung, Frank Mercurio, Robert W. Sullivan
Filed: 1 Feb 21
Utility
Substituted isoindolinones
7 Jun 22
Kyle W. H. Chan, Aparajita Hoskote Chourasia, Paul E. Erdman, Leah M. Fung, Imelda Lam, Frank Mercurio, Robert W. Sullivan, Eduardo Torres
Filed: 25 Jun 20
Utility
Protein-targeting compounds and pharmaceutical compositions thereof, and their therapeutic applications
31 May 22
Kyle W. H. Chan, Paul E. Erdman, Leah Fung, David Aaron Hecht, Imelda Lam, Robert Sullivan, Eduardo Torres
Filed: 26 May 20
Utility
Compounds targeting proteins, compositions, methods, and uses thereof
31 May 22
The present invention provides compounds that modulate protein function, to restore protein homeostasis, including cytokine, CK1α, GSPT1, aiolos, and/or ikaros activity, and cell-cell adhesion.
Kyle W. H. Chan, Paul E. Erdman, Leah M. Fung, Frank Mercurio, Robert W. Sullivan, Eduardo Torres
Filed: 11 Jan 21
Utility
Fused Thiophene Compounds
24 Mar 22
The present disclosure provides compounds that modulate protein function, to restore protein homeostasis, and cell-cell adhesion.
Kyle W.H. Chan, Aparajita Hoskote Chourasia, Paul E. Erdman, Leah M. Fung, Frank Mercurio, Robert W. Sullivan
Filed: 6 Dec 21
Utility
Bifunctional compounds
1 Feb 22
The present application provides compounds that modulate CDK protein function.
Kyle W. H. Chan, Aparajita Hoskote Chourasia, Paul E. Erdman, Leah Fung, David Aaron Hecht, Frank Mercurio, Robert Sullivan, Joseph P. Vacca
Filed: 25 Jul 19
Utility
Bicyclic compounds and methods of use
1 Feb 22
The present invention provides compounds that modulate protein function, specifically phosphodiesterase 4 (PDE4).
Robert Sullivan, Paul E. Erdman, Eduardo Torres, Leah Fung, Kyle W. H. Chan, Frank Mercurio
Filed: 11 Feb 20
Utility
Fused thiophene compounds
7 Dec 21
The present disclosure provides compounds that modulate protein function, to restore protein homeostasis, and cell-cell adhesion.
Kyle W. H. Chan, Aparajita Hoskote Chourasia, Paul E. Erdman, Leah Fung, Frank Mercurio, Robert Sullivan
Filed: 11 Jun 19
Utility
Pyrazole compounds and uses thereof
27 Jul 21
Dansu Li, Irit Snir-Alkalay, Joseph Vacca, Yinon Ben-Neriah, Avanthika Venkatachalam
Filed: 30 Jan 18
Utility
Aminoamide Compounds
20 May 21
Compounds with amino amide linkers and pharmaceutical compositions and medicaments comprising such compounds are disclosed.
Kyle W.H. Chan, Aparajita Hoskote Chourasia, Paul E. Erdman, Leah M. Fung, Frank Mercurio, Robert W. Sullivan
Filed: 1 Feb 21
Utility
Compounds Targeting Proteins, Compositions, Methods, and Uses Thereof
13 May 21
The present invention provides compounds that modulate protein function, to restore protein homeostasis, including cytokine, CKα, GSPT1, aiolos, and/or ikaros activity, and cell-cell adhesion.
Kyle W.H. Chan, Paul E. Erdman, Leah M. Fung, Frank Mercurio, Robert W. Sullivan, Eduardo Torres
Filed: 11 Jan 21
Utility
Pyrazole pyrimidine derivative and uses thereof
30 Mar 21
The present invention provides pyrazole pyrimidine derivatives which inhibit Casein kinase I (CKI) and/or Interleukin-1 receptor-associated kinase 1 (IRAKI) and methods of their manufacture, compositions comprising them and uses thereof in methods of treating malignant disease and disorders and methods for treating inflammatory diseases and disorders.
Yinon Ben Neriah, Guy Brachya, Ido Burstain, Waleed Minzel, Irit Snir-Alkalay, Joseph Vacca, Dansu Li
Filed: 12 Aug 19
Utility
Ether compounds and uses thereof
23 Feb 21
The present invention provides compounds that modulate protein function, to restore protein homeostasis and/or cell-cell adhesion.
Kyle W. H. Chan, Frank Mercurio, Aparajita Hoskote Chourasia, Leah Fung, Robert Sullivan
Filed: 18 Dec 19
Utility
Aminoamide compounds
2 Feb 21
Compounds with amino amide linkers and pharmaceutical compositions and medicaments comprising such compounds are disclosed.
Kyle W. H. Chan, Aparajita Hoskote Chourasia, Paul E. Erdman, Leah Fung, Frank Mercurio, Robert Sullivan
Filed: 11 Jun 19