67 patents
Page 4 of 4
Utility
Anti-coagulation factor XI antibodies
8 Jun 20
Antibodies that bind the apple 3 domain of human coagulation Factor XI and inhibit activation of FXI by coagulation factor XIIa as well as activation of FIX by FXIa are described.
Zhu Chen, Kenneth Ellsworth, James Milligan, Elizabeth Oldham, Dietmar Seiffert, Bianka Prinz
Filed: 11 Jun 17
Utility
ALK7 Binding Proteins and Uses Thereof
18 Mar 20
This disclosure provides ALK7-binding proteins such as anti-ALK7 antibodies, and compositions and methods for making the ALK7-binding proteins.
John Knopf, Jonathan Belk, Nathan J. Sharkey, Ravindra Kumar, Asya Grinberg, Dianne Sako, Roselyne Castonguay, Yossi Dagon
Filed: 25 Nov 19
Utility
Anti-coagulation factor XI antibodies
9 Mar 20
Antibodies that bind the apple 2 domain of human coagulation Factor XI and inhibit activation of FXI by coagulation factor XIIa are described.
Zhu Chen, Kenneth P. Ellsworth, James A. Milligan, Elizabeth Oldham, Dietmar Seiffert, Vaishnavi Ganti, Mohammad Tabrizifard, Bianka Prinz
Filed: 12 Aug 18
Utility
Anti-CD112R Compositions and Methods
5 Feb 20
The invention provides anti-CD112R antibody compositions and their use in treating cancer.
Bianka Prinz, Nadthakarn Boland, Kevin Schutz, John Bukowski, Jennifer Symonds, James Mohan, Marisella Panduro Sicheva
Filed: 18 Jul 19
Utility
ANTI-IL-27 Antibodies and Uses Thereof
18 Dec 19
The present disclosure relates to anti-IL-27 antibodies, and antigen-binding portions thereof.
Jonathan HILL, Scott CHAPPEL, Michael GLADSTONE, Bianka PRINZ, Andrew LAKE, Christine MILLER, Kerry WHITE, Jing HUA, Pamela M. HOLLAND, Matthew RAUSCH, Devapregasan MOODLEY
Filed: 21 Mar 19
Utility
ALK7 binding proteins and uses thereof
9 Dec 19
This disclosure provides ALK7-binding proteins such as anti-ALK7 antibodies, and compositions and methods for making the ALK7-binding proteins.
John Knopf, Jonathan Belk, Nathan J. Sharkey, Ravindra Kumar, Asya Grinberg, Dianne Sako, Roselyne Castonguay, Yossi Dagon
Filed: 20 Apr 17
Utility
Activin Type 2 Receptor Binding Proteins and Uses Thereof
4 Dec 19
This disclosure provides ActRII-binding proteins such as anti-ActRIIA and anti-ActRIIB antibodies, and compositions and methods for making the ActRII-binding proteins.
Ravindra Kumar, Jonathan Belk, Asya Grinberg, Dianne Sako, Roselyne Castonguay
Filed: 21 Apr 19