74 patents
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Utility
Variant Nucleic Acid Libraries for CD3
3 Nov 22
Provided herein are methods and compositions relating to CD3 libraries having nucleic acids encoding for a scaffold comprising a CD3 domain.
Aaron SATO, Qiang LIU, Mary MATHIEU, Linya WANG
Filed: 23 Mar 22
Utility
Electrochemical Polynucleotide Synthesis
13 Oct 22
Provided herein are compositions, devices, systems and methods for generation and use of biomolecule-based information for storage.
Jeremy LACKEY, Maryam HABIBIAN, YanYou LIN
Filed: 23 Mar 22
Utility
RepublicationCell Free Cloning of Nucleic Acids
13 Oct 22
Methods and devices for cell-free sorting and cloning of nucleic acid libraries are provided herein.
William BANYAI, Bill James PECK, Andres FERNANDEZ, Siyuan CHEN, Pierre INDERMUHLE, Cheng-Hsien WU, Esteban TORO
Filed: 16 May 16
Utility
Methods for Seamless Nucleic Acid Assembly
13 Oct 22
Provided herein are methods, systems, and compositions for seamless nucleic acid assembly.
Rebecca NUGENT, Siyuan CHEN, Elian LEE, Nathan RAYNARD
Filed: 13 Apr 22
Utility
Methods for Seamless Nucleic Acid Assembly
6 Oct 22
Provided herein are methods, systems, and compositions for seamless nucleic acid assembly.
Cheng-Hsien WU, Sebastian TREUSCH
Filed: 26 May 22
Utility
Variant Nucleic Acid Libraries for Tigit
29 Sep 22
Provided herein are methods and compositions relating to TIGIT libraries having nucleic acids encoding for a scaffold comprising a TIGIT domain.
Aaron SATO, Qiang LIU, Tom YUAN
Filed: 23 Mar 22
Utility
GPCR Binding Proteins and Synthesis Thereof
8 Sep 22
Provided herein are methods and compositions relating to G protein-coupled receptor (GPCR) libraries having nucleic acids encoding for a scaffold comprising a GPCR binding domain.
Jacob GLANVILLE
Filed: 18 May 22
Utility
Libraries for Identification of Genomic Variants
1 Sep 22
Provided herein are compositions and methods for identifying genomic variants.
Leonardo ARBIZA, Siyuan CHEN, Ramsey Ibrahim ZEITOUN
Filed: 17 Feb 22
Utility
Methods and Compositions Relating to Adenosine Receptors
18 Aug 22
Provided herein are methods and compositions relating to adenosine A2A receptor libraries having nucleic acids encoding for a scaffold comprising an adenosine A2A binding domain. adenosine A2A receptor libraries described herein encode for immunoglobulins such as antibodies.
Aaron SATO, Qiang LIU, Fumiko AXELROD, Linya WANG
Filed: 20 Jan 22
Utility
Barcode-based Nucleic Acid Sequence Assembly
4 Aug 22
Provided herein are methods, systems, and compositions for efficient nucleic acid assembly.
Rebecca NUGENT, Siyuan CHEN, Ross KETTLEBOROUGH, Elian LEE, Nathan RAYNARD
Filed: 15 Apr 22
Utility
Systems for Polynucleotide Construct Design, Visualization and Transactions to Manufacture the Same
4 Aug 22
The present invention disclose a computerized system for designing nucleic acid sequences for gene expression comprising; (a) a server [103] for hosting a database [106] (b) a network connection [102] and (c) a computer readable medium [101] comprising functional modules including (i) a design module for enabling designing of nucleic acid constructs; (ii) interactive user interface module for visualizing biological information relating to design operations; (iii) transaction module for purchasing a user-designed or pre-stocked nucleic acid constructs (iv) a detecting module for detecting designed nucleic acid sequences comprises harmful sequences; the system is operating in a method of: (a) visualizing biological information; (b) designing nucleic acid sequences; (c) detecting and notifying when harmful sequences are designed; (d) providing means for transactions regarding ordering and purchasing said synthesized nucleic acids.
Omri AMIRAV-DRORY, Nir BEN MOSHE
Filed: 9 Dec 21
Utility
Methods and Systems for Detecting Coronavirus
30 Jun 22
Provided herein are methods and systems for detecting coronavirus.
Aaron SATO
Filed: 21 Oct 21
Utility
Methods of Synthesizing Oligonucleotides Using Tethered Nucleotides
12 May 22
Disclosed herein are methods and compositions comprising a polymerase and a phosphorylated nucleoside, wherein the polymerase and the nucleoside are covalently linked by a cleavable linker at the terminal phosphate group.
Jeremy LACKEY, David DODD
Filed: 18 Oct 21
Utility
Methods and Compositions Relating to Chemokine Receptor Variants
5 May 22
Provided herein are methods and compositions relating to chemokine receptor libraries having nucleic acids encoding for immunoglobulins that bind to chemokine receptors.
Aaron SATO, Qiang LIU, Linya WANG, Fumiko AXELROD
Filed: 2 Nov 21
Utility
Libraries for Next Generation Sequencing
5 May 22
Provided herein are compositions and methods for Next Generation Sequencing.
Richard GANTT, Adriana ARNESON
Filed: 26 Oct 21
Utility
Nucleic Acid Based Data Storage
5 May 22
Provided herein are compositions, devices, systems and methods for the generation and use of biomolecule-based information for storage.
Bill James PECK
Filed: 18 Jan 22
Utility
Devices and Methods for Synthesis
3 Mar 22
Provided herein are compositions, devices, systems and methods for electrochemical synthesis.
Andres FERNANDEZ, Eugene P. Marsh, Maryam HABIBIAN
Filed: 26 Aug 21
Utility
Methods and Compositions Relating to GLP1R Variants
3 Mar 22
Provided herein are methods and compositions relating to glucagon-like peptide-1 receptor (GLP1R) libraries having nucleic acids encoding for immunoglobulins that bind to GLP1R.
Aaron SATO, Pankaj GARG, Qiang LIU, Fumiko AXELROD
Filed: 25 Aug 21
Utility
Compositions and Methods for Synthetic Gene Assembly
3 Mar 22
Methods and compositions are provided for assembly of large nucleic acids where the assembled large nucleic acids lack internal sequence modifications made during the assembly process.
Esteban Toro, Sebastian TREUSCH, Siyuan CHEN, Cheng-Hsien WU
Filed: 13 May 21
Utility
Devices and Methods for Light-directed Polymer Synthesis
3 Feb 22
Provided herein are compositions, devices, systems and methods for generation and use of biomolecule-based information for storage.
Jeremy LACKEY, Scott INDERMUEHLE, David DODD, Stefan PITSCH
Filed: 6 Jul 21