195 patents
Page 10 of 10
Utility
Methods for Restoring Sensitivity to TTFields in TTFields-Resistant Cancer Cells with PTGER3 Inhibitors
30 Sep 20
Methods of reducing the viability of cancer cells, preventing cancer cells of a subject from developing resistance to TTFields, and restoring sensitivity of cancer cells to TTFields by recommending or prescribing a PTGER3 inhibitor to a subject and applying an alternating electric field to the cancer cells are provided.
David TRAN, Son Bang LE, Dongjiang CHEN
Filed: 26 Mar 20
Utility
Optimizing treatment using TTfields by changing the frequency during the course of long term tumor treatment
21 Sep 20
Tumors can be treated with an alternating electric field.
Yoram Palti, Matan Dishon
Filed: 20 Apr 17
Utility
Treating Gastric Cancer Using TTFields Combined with XELOX, FOLFOX or the Individual Constituents Thereof
26 Aug 20
Methods of treating gastric cancer and reducing the viability of gastric cancer cells by administering folinic acid, fluorouracil, and oxaliplatin to a subject, and applying an alternating electric field to a target region of the subject are provided.
Einav ZEEVI, Karnit GOTLIB, Rosa S. SHNAIDERMAN, Moshe GILADI, Uri WEINBERG
Filed: 18 Feb 20
Utility
Determining a Frequency for TTFields Treatment Based on an Electrical Characteristic of Targeted Cancer Cells
26 Aug 20
Cancer treatment using TTFields (Tumor Treating Fields) can be customized to each individual subject by obtaining cancer cells from the subject, determining an electrical characteristic (e.g., dielectrophoretic forces, cell membrane capacitance, etc.) of the cancer cells, determining a frequency for the TTFields based on the determined electrical characteristic, and treating the cancer by applying TTFields to the subject at the determined frequency.
Moshe GILADI, Einav ZEEVI, Cornelia WENGER, Zeev BOMZON
Filed: 24 Feb 20
Utility
Delivering Tumor Treating Fields (TTFields) Using Implantable Transducer Arrays
26 Aug 20
Tumor treating fields (TTFields) can be delivered by implanting a plurality of sets of implantable electrode elements within a person's body.
Yoram WASSERMAN, Zeev BOMZON, Hadas Sara HERSHKOVICH, Ariel NAVEH, Moshe GILADI, Eilon KIRSON, Golan BAR-TAL, Tali VOLOSHIN-SELA
Filed: 25 Feb 20
Utility
Evaluating Quality of Segmentation of an Image into Different Types of Tissue for Planning Treatment Using Tumor Treating Fields (TTFields)
8 Jul 20
To plan tumor treating fields (TTFields) therapy, a model of a patient's head is often used to determine where to position the transducer arrays during treatment, and the accuracy of this model depends in large part on an accurate segmentation of MRI images.
Reuven R. SHAMIR, Zeev BOMZON, Mor VARDI
Filed: 6 Jan 20
Utility
Synchronizing Tumor Cells to the G2/M Phase Using TTFields Combined with Taxane or Other Anti-Microtubule Agents
10 Jun 20
Cancer cells can be synchronized to the G2/M phase by delivering an anti-microtubule agent (e.g., paclitaxel or another taxane) to the cancer cells, and applying an alternating electric field with a frequency between 100 and 500 kHz to the cancer cells, wherein at least a portion of the applying step is performed simultaneously with at least a portion of the delivering step.
Moshe GILADI, Tali VOLOSHIN-SELA
Filed: 12 Feb 20
Utility
Enhanced-Flexibility Transducer Arrays for Delivering TTFields (Tumor Treating Fields)
3 Jun 20
A transducer array for use in tumor-treating fields (TTFields) therapy is particularly suited for use in treating abdominal or thoracic cancers.
Eilon KIRSON, Yoram WASSERMAN, Noa HALAVEE
Filed: 26 Nov 19
Utility
Arrays for Delivering Tumor Treating Fields (TTFields) with Selectively Addressable Sub-Elements
20 May 20
Tumor treating fields (TTFields) can be delivered to a subject's body at higher field strengths by switching off one or more electrode elements that are overheating without switching off other electrode elements that are not overheating.
Yoram WASSERMAN, Michael KRINITSKY, Sergei KIRILLOV, Michael SHTOTLAND, Victor KAIKOV
Filed: 17 Nov 19
Utility
Creating Accurate Computational Head Models of Patients Using Datasets Combining MRI and CT Images
13 May 20
A 3D model of AC electrical conductivity of the head (or other body part) can be generated by obtaining both CT and MRI images of the head, and combining the CT and MRI images into a composite model that specifies a conductivity at each voxel of the composite model.
Ariel NAVEH, Zeev BOMZON
Filed: 11 Nov 19
Utility
Delivering Alternating Electric Fields (e.g., TTFields) to a Subject's Spinal Anatomy
29 Apr 20
This application discloses an improved approach for delivering alternating electric fields (e.g., TTFields) at a therapeutically effective strength to a target region of the spinal anatomy.
Zeev BOMZON, Ariel NAVEH, Ofir YESHARIM
Filed: 24 Oct 19
Utility
Generating Tumor Treating Fields (TTFields) with High Uniformity throughout the Brain
15 Apr 20
This application discloses configurations for arranging transducer arrays on a person's head to impose tumor treating fields (TTFields) in the brain at field strengths that are as uniform as possible throughout the entire brain.
Zeev BOMZON, Ariel NAVEH, Ofir YESHARIM
Filed: 10 Oct 19
Utility
Generating Tumor Treating Fields (TTFields) with High Uniformity throughout the Brain
15 Apr 20
This application discloses configurations for arranging transducer arrays on a person's head to impose tumor treating fields (TTFields) in the brain at field strengths that are as uniform as possible throughout the entire brain.
Zeev BOMZON, Ariel NAVEH, Ofir YESHARIM
Filed: 10 Oct 19
Utility
Treating Tumors Using TTFields Combined with ABT-751
8 Apr 20
Viability of cancer cells (e.g., glioblastoma cells) can be reduced by administering ABT-751 to the cancer cells and applying an alternating electric field with a frequency between 100 and 400 kHz (e.g., 200 kHz) to the cancer cells.
Gerben BORST, Olaf van TELLINGEN, Moshe GILADI, Mark C. de GOOIJER, Paul L.G. SLANGEN
Filed: 3 Oct 19
Utility
Treating Autoimmune Diseases Using an Alternating Electric Field to Reduce the Proliferation of T-Cells
11 Mar 20
Damage from autoimmune diseases can be prevented or minimized by positioning a plurality of electrodes in or on a subject's body, and applying an AC voltage between the plurality of electrodes so as to impose an alternating electric field through the tissue that is being attacked by the autoimmune disease and/or draining lymph nodes associated with that tissue.
Yaniv ALON, Tali VOLOSHIN-SELA, Moshe GILADI
Filed: 3 Sep 19