195 patents
Page 2 of 10
Utility
Systems and Methods for Increasing Intestinal Absorption of Therapeutic Agents
14 Dec 23
Systems and methods for increasing absorption of ingested substances into a subject's bloodstream are disclosed.
Moshe Giladi, Tali Voloshin-Sela, Lilach Avigdor, Gadi Cohen
Filed: 13 Jun 23
Utility
Methods for Treating Hormonal Disorders
14 Dec 23
A method of treating a subject, the method comprises applying an alternating electric field focused on a liver of the subject at a frequency between approximately 50 kHz and approximately 10,000 kHz, where the subject has hormonal disorder and/or polycystic ovary syndrome.
Lilach AVIGDOR, Tali VOLOSHIN-SELA
Filed: 14 Jun 23
Utility
Implantable arrays for providing tumor treating fields
12 Dec 23
An implantable apparatus for providing tumor treating fields to a target site is disclosed.
Moshe Giladi, Uri Weinberg
Filed: 2 Jun 21
Utility
Compositions and methods of altering the electric impedance to an alternating electric field
5 Dec 23
Disclosed are methods of altering the electric impedance to an alternating electric field in a target site of a subject, comprising introducing a nanoparticle to a target site in the subject; and applying an alternating electric field to the target site of the subject, wherein the electric impedance in the target site of the subject to the alternating current is altered.
Hadas Hershkovich, Tali Voloshin-Sela, Ze'ev Bomzon
Filed: 30 Nov 20
Utility
Compositions And Methods For Treating With A Combination Of Alternating Electric Fields And Ion Channel Inhibitors
30 Nov 23
Disclosed are methods of treating a subject having cancer comprising applying alternating electric fields to a target site of the subject for a period of time, the alternating electric fields having a frequency and field strength, wherein the target site comprises one or more cancer cells, and administering an ion channel inhibitor to the subject.
Stuart Smith, Michele Mazzanti
Filed: 31 Mar 23
Utility
Fabricating organic light emitting diodes (OLEDs) using tubulin
14 Nov 23
Organic light-emitting diodes are disclosed comprising an electron transport layer and a hole transport layer.
Aarat Pratyaksh Kalra, Jack Adam Tuszynski, Sahil Deepak Patel, Karthik Shankar
Filed: 22 Jun 21
Utility
Electrode Assembly Having Perforated Anisotropic Layer, And Systems And Methods Of Applying Tumor-Treating Fields Using Same
5 Oct 23
An apparatus includes: at least one electrode element; a layer of anisotropic material; a first layer of conductive adhesive positioned between a skin-facing surface of the at least one electrode element and an outwardly facing surface of the layer of anisotropic material; and a skin contact layer.
Yoram Wasserman, Stas Obuchovsky, Nataliya Kuplennik, David Shapiro
Filed: 31 Mar 23
Utility
Using Interleaved Cooling Periods to Increase the Peak Intensity of Tumor Treating Fields
5 Oct 23
Alternating electric fields (e.g., TTFields) may be induced in a target region in a subject's body by applying, during each of a plurality of first time intervals, a series of pulses of alternating current between electrode elements positioned on or in the subject's body.
Tali VOLOSHIN-SELA, Lilach AVIGDOR, Reuven SHAMIR
Filed: 30 Mar 23
Utility
Devices, Systems, And Methods For Applying Tumor-Treating Fields
5 Oct 23
Assemblies for use in applying TTFields are disclosed.
Yoram Wasserman, Stas Obuchovsky, Nataliya Kuplennik, David Shapiro
Filed: 31 Mar 23
Utility
Delivering Tumor Treating Fields (TTFields) Using Implanted Sheets of Graphite
5 Oct 23
Alternating electric fields (e.g., tumor treating fields, a.k.a.
Yoram WASSERMAN, Stas OBUCHOVSKY, Nataliya KUPLENNIK, David SHAPIRO
Filed: 31 Mar 23
Utility
Electrode Array Having a Semi-liquid Conductive Gel
5 Oct 23
An assembly, a system, and a method of use for an electrode array having a semi-liquid conductive gel are herein disclosed.
Richard Deslauriers
Filed: 29 Mar 23
Utility
Alternating Electric Field Waveform for Electrosensation Reduction
5 Oct 23
A method to treat a target region of a subject's body with an alternating electric field, the method including: applying the alternating electric field to the target region of the subject's body at a first frequency while increasing an intensity of the alternating electric field from zero to a target intensity; and changing the frequency of the alternating electric field from the first frequency to a target frequency while maintaining the alternating electric field at the target intensity, wherein the target frequency and the target intensity have a known efficacy for treating the target region of the subject's body with the alternating electric field; and wherein the first frequency is greater than the target frequency.
Moshe GILADI, Lilach AVIGDOR
Filed: 30 Mar 23
Utility
Reducing Electrosensation Whilst Treating a Subject Using Alternating Electric Fields by Pairing Transducer Arrays Together
5 Oct 23
When treating a subject using alternating electric fields (e.g., using TTFields to treat a tumor, or using alternating electric fields to increase the permeability of the blood brain barrier), some subjects experience an unpleasant electrosensation effect.
Moshe GILADI
Filed: 30 Mar 23
Utility
Geometrically Fitted Transducers for Tumor Treating Fields
28 Sep 23
A transducer apparatus for delivering tumor treating fields to a subject’s body, the transducer apparatus including: an array of electrode elements, the array configured to be positioned over the subject’s body with a face of the array facing the subject’s body; wherein, when viewed from a direction perpendicular to the face of the array, an outer perimeter of the array substantially tracing the electrode elements has a shape including: at least one convex edge portion protruding away from a centroid of the array; and at least one concave edge portion recessed toward the centroid of the array.
Noa HALAVEE, Shalom STRAUSS
Filed: 21 Mar 23
Utility
Synchronizing Tumor Cells to the G2/M Phase Using TTFields Combined with Taxane or Other Anti-Microtubule Agents
10 Aug 23
Cancer cells can be synchronized to the G2/M phase by delivering an anti-microtubule agent (e.g., paclitaxel or another taxane) to the cancer cells, and applying an alternating electric field with a frequency between 100 and 500 kHz to the cancer cells, wherein at least a portion of the applying step is performed simultaneously with at least a portion of the delivering step.
Moshe GILADI, Tali VOLOSHIN-SELA
Filed: 14 Apr 23
Utility
Applying Tumor Treating Fields (TTFields) Via Electrodes Embedded into Skull Implants
10 Aug 23
Tumors inside a person's head (e.g., brain tumors) can be treated using tumor treating fields (TTFields) by positioning capacitively coupled electrodes on opposite sides of the tumor, and applying an AC voltage between the electrodes.
Yoram WASSERMAN, Uri WEINBERG, Zeev BOMZON
Filed: 13 Apr 23
Utility
Electrode Assembly with a Skin Contact Layer Comprising a Conductive Adhesive Composite, and Systems and Methods of Applying Tumor Treating Fields Using Same
3 Aug 23
Alternating electric fields (e.g., TTFields) may be applied to a subject's body using an electrode assembly that includes a skin contact layer formed at least partially of a conductive adhesive.
Rosa S. SHNAIDERMAN, Yoram WASSERMAN, Stas OBUCHOVSKY, Nataliya KUPLENNIK, David SHAPIRO
Filed: 28 Feb 23
Utility
Optimizing treatment using TTFields by changing the frequency during the course of long term tumor treatment
18 Jul 23
Tumors can be treated with an alternating electric field.
Yoram Palti, Matan Dishon
Filed: 17 Sep 20
Utility
Selecting Values of Parameters for Treatment Using Tumor Treating Fields (TTFields)
13 Jul 23
Characteristics of alternating electric fields that will be applied to a target region in a subject’s body can be selected by applying different sets of pulses between electrode elements positioned on opposite sides of the target region.
Moshe GILADI, Reuven R. SHAMIR, Kirill STEPOVOY
Filed: 28 Dec 22
Utility
Methods, Systems, and Apparatuses for Managing Transducer Array Placement
29 Jun 23
Methods, systems, and apparatuses are described for managing placement of transducer arrays on a subject/patient.
Hadas Sara HERSHKOVICH, Zeev BOMZON, Gil ZIGELMAN, Shira LUK-ZILBERMAN, Ori Kook, Oren Ben Zion BAKALO
Filed: 2 Mar 23