195 patents
Page 3 of 10
Utility
Reducing Electrosensation Whilst Treating a Subject Using Alternating Electric Fields by Using Larger Cathodes and Smaller Anodes
29 Jun 23
When treating a subject using alternating electric fields (e.g., using TTFields to treat a tumor), some subjects experience an electrosensation effect.
Kristen W. CARLSON
Filed: 28 Dec 22
Utility
Applying tumor treating fields (TTFields) via electrodes embedded into skull implants
23 May 23
Tumors inside a person's head (e.g., brain tumors) can be treated using tumor treating fields (TTFields) by positioning capacitively coupled electrodes on opposite sides of the tumor, and applying an AC voltage between the electrodes.
Yoram Wasserman, Uri Weinberg, Zeev Bomzon
Filed: 24 Jul 20
Utility
Electrode Assembly with Non-Hydrogel Conductive Adhesive Layer and Methods of Applying Tumor Treating Fields Using Same
18 May 23
Disclosed are electrode assemblies having at least two layers of conductive adhesive material separated by an anisotropic material and methods of using the electrode assemblies in Tumor Treating Fields (TTFields) therapy.
Yoram Wasserman, Stas Obuchovsky, Nataliya Kuplennik, David Shapiro
Filed: 15 Nov 22
Utility
Adjusting Tumor Treating Fields Simulation and Treatment Using Molecular Imaging
18 May 23
A computer-implemented method to determine placement of transducers on a subject's body for applying tumor treating fields, the method including: determining a pair of locations on the subject's body for placement of a pair of transducer arrays based on image data; receiving a detected concentration of a target molecule within a target region of the subject's body from a molecular imaging apparatus, the concentration of the target molecule being detected after tumor treating fields are induced between the pair of transducer arrays; determining, based on the detected concentration of the target molecule, how the tumor treating fields were distributed in the target region; determining a recommendation of a second pair of locations on the subject's body for placement of the pair of transducer arrays based on the distribution of the tumor treating fields in the target region; and outputting the recommendation of the second pair of locations to a user.
Tali VOLOSHIN-SELA, Lilach AVIGDOR, Reuven Ruby Shamir
Filed: 17 Oct 22
Utility
TTField treatment with optimization of electrode positions based on low frequency (<1MHZ) AC conductivity estimates derived from two MRI images having different repetition times
16 May 23
A 3D model of AC electrical conductivity (at a given frequency) of an anatomic volume can be created by obtaining two MRI images of the anatomic volume, where the two images have different repetition times.
Cornelia Wenger, Catherine Tempel-Brami, Hadas Sara Hershkovich, Moshe Giladi, Zeev Bomzon
Filed: 9 Apr 19
Utility
System for Viewing Cell Cultures Under a Microscope whilst Applying TTFields
11 May 23
An apparatus includes a bottom panel with a transparent region and ceramic sidewalls affixed to the bottom panel to form a container.
Moshe GILADI, Yoram WASSERMAN, Yoram PALTI, Michael KRINITSKY, Michael SHTOTLAND
Filed: 3 Jan 23
Utility
Methods, Systems, and Apparatuses for Combined Tumor Treating Fields and Mental Health Therapy
11 May 23
Methods, systems, and apparatuses are described for using electrical stimulation to combine (e.g., concomitantly) tumor treating fields (TTFIelds) and mental health therapy (e.g., anti-depression therapy, anti-anxiety therapy, etc.).
Kristen W. Carlson, Zeev Bomzon
Filed: 21 Dec 20
Utility
Optimizing positions of electrodes for applying tumor treating fields (TTFields) by adding a dipole to a 3D model
9 May 23
When electrodes are used to impose an electric field in target tissue within an anatomic volume (e.g., to apply TTFields to treat a tumor), the position of the electrodes can be optimized by generating a 3D map of electrical conductivity or resistivity of the anatomic volume.
Yoram Wasserman, Cornelia Wenger, Pedro Michael Cavaleiro Miranda, Zeev Bomzon, Noa Urman, Eilon Kirson, Yoram Palti
Filed: 3 Mar 21
Utility
Compositions and Methods for Testing Adverse Skin Events
13 Apr 23
Disclosed are apparatuses comprising at least one electrode element having a skin-facing surface; a skin contact layer comprising an adhesive composite, and an adhesive tape or bandage.
AVISHAI NAHSHONI
Filed: 27 Sep 22
Utility
Methods, systems, and apparatuses for managing transducer array placement
4 Apr 23
Methods, systems, and apparatuses are described for managing placement of transducer arrays on a subject/patient.
Hadas Sara Hershkovich, Zeev Bomzon, Gil Zigelman, Shira Luk-Zilberman, Ori Kook, Oren Ben Zion Bakalo
Filed: 4 May 20
Utility
Perforated Hydrogel Configurations and Methods of Production and Use Thereof
30 Mar 23
Improved hydrogel configurations for use with a TTField-generating system is disclosed.
Richard Deslauriers
Filed: 7 Dec 22
Utility
Reducing Electrosensation Whilst Treating A Subject Using Alternating Electric Fields
30 Mar 23
When treating a subject using alternating electric fields (e.g., using TTFields to treat a tumor), some subjects experience an electrosensation effect when the alternating electric field switches direction.
Kristen W. CARLSON
Filed: 29 Sep 22
Utility
Method and System for Applying Tumor Treating Fields Interfacing with Hair Follicles
30 Mar 23
A system and method for delivering TTFields are herein described.
Richard Deslauriers
Filed: 30 Sep 22
Utility
Delivering tumor treating fields (TTFields) using implantable transducer arrays
21 Mar 23
Tumor treating fields (TTFields) can be delivered by implanting a plurality of sets of implantable electrode elements within a person's body.
Yoram Wasserman, Zeev Bomzon, Hadas Sara Hershkovich, Ariel Naveh, Moshe Giladi, Eilon Kirson, Golan Bar-Tal, Tali Voloshin-Sela
Filed: 12 Sep 22
Utility
Temperature Independent Method and System for Applying Ttfields
16 Mar 23
A system and method for delivering TTFields are herein described.
Richard Deslauriers
Filed: 14 Sep 22
Utility
High voltage, high efficiency sine wave generator that prevents spikes during amplitude adjustments and switching of channels
7 Mar 23
This application describes a variety of approaches for generating high voltage sinusoidal signals whose output voltage can be adjusted rapidly, without introducing high-frequency artifacts on the output.
Yoram Wasserman
Filed: 17 Dec 20
Utility
Transducer Apparatuses with Electrode Array Shaped to Reduce Edge Effect In Delivering Tumor Treating Fields to a Subject's Body
2 Mar 23
A transducer apparatus for delivering tumor treating fields to a subject's body, the transducer apparatus including: an array of electrode elements electrically coupled to each other, the array including all electrode elements present on the transducer apparatus, the array configured to be positioned over the subject's body with a face facing the subject's body; wherein, when viewed from a direction perpendicular to the face of the array, an outer perimeter of the array substantially tracing the electrode elements of the array has a rounded convex shape; a number of the electrode elements of the array are peripheral electrode elements defining the outer perimeter of the array, the peripheral electrode elements substantially surrounding any other electrode elements of the array; and wherein for each peripheral electrode element, at least a portion of a length of a perimeter of the peripheral electrode element is touching the outer perimeter of the array.
Tal MARCIANO, Smadar ARVATZ, Boaz MARSAULT
Filed: 11 Aug 22
Utility
Electrode Assembly with a Skin Contact Layer Comprising a Conductive Adhesive Composite, and Systems and Methods of Applying Tumor Treating Fields Using Same
2 Mar 23
Alternating electric fields (e.g., TTFields) may be applied to a subject's body using an electrode assembly that includes a skin contact layer formed at least partially of a conductive adhesive composite.
ROSA SHNAIDERMAN, YORAM WASSERMAN, STAS OBUCHOVSKY, NATALIYA KUPLENNIK, DAVID SHAPIRO
Filed: 30 Aug 22
Utility
Inhibiting viral infection using alternating electric fields
21 Feb 23
Viral infections in a target region can be inhibited by imposing an alternating electric field in the target region for a duration of time.
Noa Kaynan, Tali Voloshin-Sela, Moshe Giladi, Eilon Kirson
Filed: 9 Jul 19
Utility
Transducer Apparatuses with Electrode Element Spacing to Reduce Edge Effect In Delivering Tumor Treating Fields to a Subject's Body
16 Feb 23
A transducer apparatus for delivering tumor treating fields to a subject's body, the transducer apparatus including: a plurality of electrode elements; wherein the plurality of electrode elements comprises a first electrode element and a second electrode element, wherein the first electrode element and the second electrode element are substantially located in a plane of the transducer apparatus; and when viewed from a direction perpendicular to the plane, the first electrode element and the second electrode element have edges located adjacent each other without any other electrodes between them, wherein the edges of the first electrode element and the second electrode element extend parallel to each other along their length.
Yoram WASSERMAN, Stas OBUCHOVSKY, Nataliya KUPLENNIK, David SHAPIRO, Elie YAACOBI, Golan BAR-TAL, Noa HALAVEE
Filed: 11 Aug 22