110 patents
Page 2 of 6
Utility
High-throughput Automated Strain Library Generator
9 Feb 23
A method for automated, high throughput cellular library generation is disclosed.
Sara da Luz Areosa CLETO, Philip D. WEYMAN
Filed: 4 Oct 22
Utility
Filament Comprising a Thermoplastic Polyimide and Three-dimensional Body Made from the Filament
26 Jan 23
In one embodiment, a filament can comprise a thermoplastic polyimide, wherein the filament is adapted for use in a fused filament fabrication process and the thermoplastic polyimide may have a glass transition temperature not greater than 215° C.
Patrick Gerardus DUIS, Kenneth Angus KEMPINSKI, Justin KERSZULIS
Filed: 30 Jun 22
Utility
Compositions and Methods for Synthesis of Terpenoids
10 Nov 22
The disclosure relates to the biosynthesis of terpenoids, such as, for example, geraniol and derivatives thereof, using genetic engineering.
Stefan DE KOK, Warren LAU, Fern MCSORLEY, Hermann-Josef MEYER, Zach SERBER, Grayson WAWRZYN
Filed: 26 Jun 20
Utility
Downscaling Parameters to Design Experiments and Plate Models for Micro-organisms at Small Scale to Improve Prediction of Performance at Larger Scale
13 Oct 22
Systems, methods and computer-readable media are provided for designing experiments for organisms at a first scale to generate first-scale performance data used in predicting performance of the organisms at a second, larger scale.
Stefan De Kok, Peter Enyeart, Richard Hansen, Trent Hauck, Crystal Humphries, Sarah Lieder, Zachariah Serber, Erin Shellman, Amelia Taylor, Thomas Treynor, Kristina Tyner
Filed: 5 May 20
Utility
Promoters from Corynebacterium Glutamicum
13 Oct 22
Provided are native promoters comprising polynucleotides isolated from Corynebacterium glutamicum, and mutant promoters derived therefrom, which may be used to regulate, i.e., either increase or decrease, gene expression.
Zachariah SERBER, Katherine G. GORA, Shawn P. MANCHESTER
Filed: 25 Mar 22
Utility
Engineered Biosynthetic Pathways for Production of Cystathionine by Fermentation
6 Oct 22
The present disclosure describes the engineering of microbial cells for fermentative production of cystathionine and provides novel engineered microbial cells and cultures, as well as related cystathionine production methods.
Cara Ann Tracewell, Alexander Glennon Shearer, Anupam Chowdhury, Steven M. Edgar
Filed: 24 Jun 20
Utility
Powder Composition Comprising Polyimide Particles, Three-dimensional Polyimde-based Body, and Method of Forming the Body
22 Sep 22
In one embodiment, a powder composition can comprise polyimide particles, wherein the polyimide particles can have a glass transition temperature of not greater than 200° C. and a crystallinity of not greater than 20%.
Patrick Gerardus Duis, John Colby Chastain, Justin Kerszulis, Kenneth Kempinski
Filed: 17 Mar 22
Utility
Engineered Biosynthetic Pathways for Production of 3-AMINO-4-HYDROXYBENZOIC Acid by Fermentation
8 Sep 22
The present disclosure describes the engineering of microbial cells for fermentative production of 3-amino-4-hydroxybenzoic acid and provides novel engineered microbial cells and cultures, as well as related 3-amino-4-hydroxybenzoic acid production methods.
Cara Ann Tracewell, Alexander Glennon Shearer
Filed: 10 Aug 20
Utility
HTP Genomic Engineering Platform
1 Sep 22
The present disclosure provides a HTP microbial genomic engineering platform that is computationally driven and integrates molecular biology, automation, and advanced machine learning protocols.
Zachariah SERBER, Erik Jedediah DEAN, Shawn MANCHESTER, Katherine GORA, Michael FLASHMAN, Erin SHELLMAN, Aaron KIMBALL, Shawn SZYJKA, Barbara FREWEN, Thomas TREYNOR, Kenneth S. BRUNO
Filed: 17 May 22
Utility
Laboratory Automation System Implementing Efficient Path for Material and Labware Transfers
18 Aug 22
Systems, methods and computer-readable media are provided for determining a sequential ordering of predefined transfers for transferring an object from source points of a source array to destination points of a destination array in a laboratory automation system.
Christopher Bremner
Filed: 26 Jun 20
Utility
Manipulation of Genes Involved In Signal Transduction to Control Fungal Morphology During Fermentation and Production
18 Aug 22
The present disclosure provides a microbial genomic engineering method and system for transforming, screening, and selecting filamentous fungal cells that have altered morphology and/or growth under specific growth conditions.
Kenneth S. BRUNO, Sachin JAIN, Brandon PFANNENSTIEL, Edyta SZEWCZYK
Filed: 21 Mar 22
Utility
Microbial Engineering Methods and Systems for Optimizing Microbe Fitness
21 Jul 22
The present disclosure provides a microbe engineering platform that permits optimization of microbe fitness levels to optimize a microbe's suitability for industrial fermentation.
WILLIAM SERBER, ERIK JEDEDIAH DEAN
Filed: 6 Dec 21
Utility
Engineered Biosynthetic Pathways for Production of L-homocysteine by Fermentation
26 May 22
The present disclosure describes the engineering of microbial cells for fermentative production of L-homocysteine and provides novel engineered microbial cells and cultures, as well as related L-homocysteine production methods.
Michael Shareef Siddiqui, Alexander Glennon Shearer, Franklin Lu, Stefan de Kok, Cara Ann Tracewell, Steven M. Edgar, Jennifer Yip
Filed: 24 Mar 20
Utility
HTP Genomic Engineering Platform for Improving Fungal Strains
12 May 22
A HTP genomic engineering platform for improving filamentous fungal cells that is computationally driven and integrates molecular biology, automation, and advanced machine learning protocols is provided.
Vytas SunSpiral, Jennifer Fredlund, Hassan Abdulla, Paolo Boccazzi, Sean Poust, Sara da Luz Areosa Cleto, Brian Chaikind, Dylan Vaughan, Kenneth S. Bruno, Patrick Westfall, Edyta Szewczyk, Kyle Rothschild-Mancinelli, Arthur Muir Fong, III
Filed: 26 Jan 22
Utility
Polymer Compositions Comprising Compounds Derived from Biology
31 Mar 22
A compound comprises a moiety selected from a cyclic dimer of a first and a second amino acid or a 2.5-diketopiperazine made from an amino acid.
John J. McNamara, Carol A. Koch, Michael William Angus MacLean, Stephen Lo, Ke Li, Jason P. Safko, Md Nazim Uddin, Jenny Shao, Joachim C. Ritter
Filed: 30 Dec 19
Utility
Elastomeric Adhesives Comprising Bio-derived Compounds
31 Mar 22
The present disclosure addresses elastomeric adhesives and elastomers that include a modified amine.
Nandita Bhagwat, John Dickens, Joachim C. Ritter, Gerald A. Vandezande, Jonathon E. Vandezande, John J. McNamara
Filed: 21 Jan 20
Utility
Microbial Strain Design System and Methods for Improved Large-scale Production of Engineered Nucleotide Sequences
10 Mar 22
The generation of a factory order includes receiving an expression indicating an operation on a first sequence operand and a second sequence operand.
Barbara Frewen, Aaron Kimball
Filed: 16 Sep 21
Utility
Engineered Biosynthetic Pathways for Production of 1,5-DIAMINOPENTANE by Fermentation
3 Feb 22
The present disclosure describes the engineering of microbial cells for fermentative production of 1,5-diaminopentane and provides novel engineered microbial cells and cultures, as well as related 1,5-diaminopentane production methods.
Aaron Miller, Zhihao Wang, Jeffrey Mellin, Murtaza Shabbir Hussain, Steven M. Edgar
Filed: 21 Nov 19
Utility
Engineered Biosynthetic Pathways for Production of 2-OXOADIPATE by Fermentation
3 Feb 22
The present disclosure describes the engineering of microbial cells for fermentative production of 2-oxoadipate and provides novel engineered microbial cells and cultures, as well as related 2-oxoadipate production methods.
Anupam Chowdhury, Steven M. Edgar, Alexander Glennon Shearer, Cara Ann Tracewell, Stepan Tymoshenko, Zhihao Wang
Filed: 25 Nov 19
Utility
Systems and Methods for High-throughput Automated Strain Generation for Non-sporulating Fungi
3 Feb 22
Embodiments disclosed include systems and methods to generate and/or improve non-sporulating filamentous fungal cells using high-throughput techniques.
Benjamin Knox, Nasim Mansoori Zangir, Ryan Evan Martinez, Hassan Abdulla
Filed: 28 Jul 21