104 patents
Utility
Wearable Assistance Devices and Methods of Operation
18 Jan 24
Wearable assistance devices and methods of operating the same are provided.
Karl Zelik, Matthew Yandell, Dustin Howser, Erik Lamers
Filed: 27 Sep 23
Utility
Patient-customized electrode arrays based on patient-specific cochlear information, and designing/selecting methods and applications of same
16 Jan 24
A method for designing a patient-customized EA or selecting an existing EA that fits the patient best includes segmenting shapes of SOIs of the cochlea in a pre-operative CT image using a shape model; defining a 3D curve of interest within the shape model of the SOIs as a sequence of points-; automatically transforming the defined 3D curve to the pre-operative CT image so as to obtain a structure curve in the cochlea; determining a length and curvatures of the structure curve at the sequence of points; and designing a patient-customized EA or selecting an existing EA based on the determined length and curvatures of the structure curve such that after the EA shape model, which estimates the resting state shape of the EA, is rigidly registered to the structure curve in the cochlea, the EA shape model has a registration error smaller than a preset value.
Jack H. Noble, Robert F. Labadie, Benoit M. Dawant
Filed: 7 Jun 21
Utility
Multi-shot echo planar imaging using reordered segments and recursive radio frequency pulse design giving matched slice profiles across segments
16 Jan 24
Described here are systems and methods for producing images with a magnetic resonance imaging (“MRI”) system using a high-resolution, motion-robust, artifact-free segmented echo planar imaging (“EPI”) technique.
Avery J. L. Berman, Jonathan R. Polimeni, William A. Grissom, Kawin Setsompop, Thomas Witzel
Filed: 27 Mar 20
Utility
Antagonists of the Muscarinic Acetylcholine Receptor M4
11 Jan 24
Aaron M. Bender, Matthew Spock, Melissa A. Korkmaz-Vaisys, Craig W. Lindsley, P. Jeffrey Conn
Filed: 18 Nov 21
Utility
Large-scale Epigenomic Reprogramming Links Anabolic Glucose Metabolism to Distant Metastasis During the Evolution of Pancreatic Cancer Progression
11 Jan 24
The present invention relates to a method of identifying epigenetic reprogramming.
Oliver McDonald, Xin Li, Christine A. Iacobuzio-Donahue, Andrew P. Feinberg
Filed: 1 Aug 23
Utility
Valveless Devices for Pulsatile Fluid Flow
11 Jan 24
Described are pumps structured for moving fluids with pulsatile flow.
Marvin J. Slepian, Eric J. Barth, Mengtang Li
Filed: 12 Aug 21
Utility
Control method for a robotic system
9 Jan 24
An exemplary robotic system includes a plurality of controllable joints and a controller.
Michael Goldfarb, Andres Martinez-Guerra, Brian Lawson
Filed: 30 Apr 19
Utility
Compounds and Methods for Scavenging Dicarbonyl Electrophiles
4 Jan 24
Keith T. Wilson, John A. Oates, Olivier Boutaud, Venkataraman Amarnath, Erica J. Carrier, Alain P. Gobert
Filed: 10 Jul 23
Utility
Compositions and Methods for Targeting the Interaction of Host MYO5B+D and Coronavirus M Proteins
4 Jan 24
Disclosed herein is a method for treating or preventing a coronavirus infection in a subject that involves administering to the subject an effective amount of a composition comprising an agent that disrupts the binding of coronavirus membrane glycoprotein (M protein) and Myosin Vb protein (MYO5B).
Frédéric TANGY, Pierre-Olivier VIDALAIN, James R. GOLDENRING, Joseph T. Roland, Lynne A. LAPIERRE, Elizabeth MANNING, Cornelis Alexander Maria DE HAAN
Filed: 3 Nov 21
Utility
Binary compositions as disruptors of Orco-mediated odorant sensing
2 Jan 24
In one aspect, the invention relates to binary compositions that disrupt ORco-mediated odorant sensing.
Laurence J. Zwiebel, Ian M. Romaine, Sam Ochieng, Alex Gregory Waterson, Gary A. Sulikowski
Filed: 26 Aug 20
Utility
Therapeutic Window for Citrulline Therapy
21 Dec 23
This invention is directed to citrulline therapy, where citrulline is administered to achieve a newly recognized therapeutic window.
Gurdyal Kalsi, Marshall Summar, Frederick E. Barr, Omar Ayyub, Gary R. Pasternack
Filed: 21 Jun 22
Utility
Multi-articulated Catheters with Safety Methods and Systems for Image-guided Collaborative Intravascular Deployment
21 Dec 23
Systems and method for controlling the bending of a robotic catheter.
Nabil Simaan, Giuseppe Del Giudice, Colette Abah, Rohan V. Chitale
Filed: 7 Mar 23
Utility
Rigid Phantom for End-to-end Verification of Adaptive Radiotherapy Systems
14 Dec 23
Systems and methods associated with a phantom assembly are provided.
Adam D. YOCK, Abby E. DARE, Michael Price
Filed: 28 Aug 23
Utility
SIMULTANEOUS FOCUSED ULTRASOUND AND fMRI AND APPLICATION OF FOCUSED ULTRASOUND OUTSIDE OF MRI ENVIRONMENT
14 Dec 23
A workflow has been developed that enables initially mapping of a focused ultrasound (FUS) beam using magnetic resonance (MR) thermometry or MR-acoustic radiation force imaging (MR-ARFI) while working within the MRI device.
Charles F. Caskey, Limin Chen, William A. Grissom, Peter E. Konrad, Benoit M. Dawant, Willliam J. Rodriguez
Filed: 8 Oct 21
Utility
System and method for B1-selective spatial encoding using magnetic resonance
12 Dec 23
The present application provides a system and method for using a nuclear magnetic resonance (NMR) system.
Mark A. Griswold, William A. Grissom
Filed: 30 Dec 20
Utility
Magnetic particle imaging using an ultrasonic driving field
12 Dec 23
A system and method of magnetic particle imaging (MPI) are disclosed.
William A. Grissom, Charles F. Caskey
Filed: 8 Feb 22
Utility
L-dna Encrypted Tracers
7 Dec 23
The present disclosure is directed to the use of left-handed DNA (L-DNA) tracer to identify the source, track the distribution, and validate the integrity of products or resources that are highly regulated, valuable, or hazardous (e.g., pharmaceuticals, treated water, chemicals, designer products, and ammunitions).
Nicholas M. ADAMS, Frederick R. HASELTON
Filed: 26 May 23
Utility
Cytoplasmic incompatibility factors and methods for controlling anthropods
5 Dec 23
The disclosure relates to genetically modified bacteria, genetically modified arthropods, and methods for controlling and/or reducing arthropod populations.
Jason Metcalf, Seth R. Bordenstein, Daniel Lepage, Sarah Bordenstein, Mark Hochstrasser, John F. Beckmann, Judith Ronau
Filed: 9 Jun 17
Utility
Cleavable agents
5 Dec 23
The present disclosure is directed to a cleavable agent for enhanced magnetic resonance generally corresponding to the formula Y-L-R, wherein Y represents a catalyst-binding moiety having at least one isotopically labeled heteroatom, L represents a cleavable bond, and R represents a hyperpolarized payload having at least one isotopically labeled carbon.
Boyd M. Goodson, Eduard Y. Chekmenev, Bryce E. Kidd, Jamil A. Mashni, Miranda Limbach, Yuqing Hou, Fan Shi
Filed: 27 Nov 19
Utility
Double offsets and powers magnetization transfer ratio for specific magnetization transfer magnetic resonance imaging
5 Dec 23
Imaging methods for assessing the macromolecular content, such as myelin, are of great interest for understanding brain tissue microstructure, and have shown potentials in diagnosing and prognosing demyelinating diseases. for example.
ZhongLiang Zu
Filed: 7 Nov 22