3525 patents
Page 18 of 177
Utility
Split Intein-based Selection for Peptide Binders
20 Jul 23
Disclosed herein, in some embodiments, non-naturally occurring proteins (e.g., non-naturally occurring modified proteins) that may be useful in the treatment of bacterial and viral infections, including SARS-CoV-2 infection, host cells comprising the same, and methods of treating bacterial and viral infections including SARS-CoV-2 infection.
Christopher A. Voigt, Andrew King, Emerson Glassey
Filed: 11 Jun 21
Utility
Inorganic-biological Hybrid System for Biofuel Production
20 Jul 23
A system for biofuel production can include a cell, a nanoparticle on a surface of the cell, and an irradiation unit configured to expose the cell to irradiation.
Shalmalee Pandit, Angela Belcher
Filed: 9 Jun 21
Utility
d9464gkox9uomb iscse2o8wpo
18 Jul 23
An agent activated non-metal antenna for an ultra-high frequency (UHF) wireless sensor having a radio frequency identification (RFID) tag in electronic communication with the non-metal antenna, and a wireless data communication integrated circuit (IC), includes a conductive stimuli-responsive hydrogel material configured to be inactive prior to an interaction with an activating agent and active upon the interaction with the activating agent.
Sanjay E. Sarma, Rahul Bhattacharyya, Joshua E. Siegel, Alex Armengol Urpi, Pankhuri Sen, Sai Nithin Reddy Kantareddy
Filed: 28 Oct 21
Utility
4z0hun12qi85evaogh6bco8tuio7
18 Jul 23
Provided are improved compositions and methods for achieving gene therapy in hematopoietic cells and hematopoietic precursor cells, including erythrocytes, erythroid progenitors, and embryonic stem cells.
Philippe Louis Leboulch, Robert Pawliuk, Karen Westerman
Filed: 16 Mar 20
Utility
djsorv9cm1 6byg6p760wwkwiu3n60af6vi
18 Jul 23
A method for the systemic delivery of a polypeptide within a subject is provided by creating genetically modified skin cells via topical introduction of a genetically engineered virus which delivers a nucleic acid encoding a therapeutic polypeptide for expression by the skin cells, wherein the expressed therapeutic polypeptide is secreted by the skin cells and is introduced into the circulatory system of the subject.
Denitsa M. Milanova, George M. Church, Noah Davidsohn, Carl Schoellhammer, Robert S. Langer, Anna I. Mandinova, Carlo Giovanni Traverso
Filed: 14 May 18
Utility
92bnf9oquivf2hkiwz6qzd
18 Jul 23
The present invention relates to the analysis of complex single cell sequencing libraries.
Paul Blainey, Navpreet Ranu, Todd Gierahn, J. Christopher Love
Filed: 23 Oct 18
Utility
cg1uvhvvtxotevvyssw8q6iie a7ggln9m001bh8bfu6i9pbs
18 Jul 23
The present invention provides for methods to obtain multiple information-rich samples at different time points from the same cell while minimally disrupting the cell.
Paul Blainey, Jacob Borrajo, Mohamad Najia, Atray Dixit
Filed: 21 Sep 17
Utility
x2fu5krvuk36ezy7gyoumeatwhkz1bsu7liq696tmpdsbv1i1no
18 Jul 23
A retrographic sensor includes a transparent structure, a transparent elastomeric pad, and an at least partially reflective layer.
Edward Adelson, Branden Romero, Filipe Fernandes Veiga
Filed: 15 Oct 20
Utility
s18aqinpu8sbl05yk7dkcvyst93w124yfabpvm7y9ap4fa7b1l8s4zx
18 Jul 23
The present invention relates to methods and products associated with in vivo enzyme profiling.
Sangeeta N. Bhatia, Geoffrey A. von Maltzahn, Gabriel A. Kwong
Filed: 6 Nov 20
Utility
t1ee0l3rwjjfc0738vhc55z6l7oryrm0l7t763leoofxoo
18 Jul 23
Systems and methods for implementing confidential communications between nodes of a network provide reduced power consumption, require less memory, and provide improved security, relative to previously-known systems and method.
Anantha P. Chandrakasan, Chiraag Juvekar, Utsav Banerjee
Filed: 14 Jun 21
Utility
h5dcoyvsy c6pthxhum8xer17dawd4k5fvdcjwnvczhpsqzdle33g0
13 Jul 23
Conventional optical lithography uses masks with static patterns that are expensive and labor intensive to produce.
Aik Jun Tan, Mantao Huang, Geoffrey S. D. Beach
Filed: 2 Apr 21
Utility
zyhhk3mfsf9o1n3gpolqj53emnc5jq9s41bl1t62vfk4cta0fd
13 Jul 23
Self-righting articles, such as self-righting capsules for administration to a subject, are generally provided.
Robert S. Langer, Carlo Giovanni Traverso, Alex G. Abramson, Michael Williams, Jacob Wainer
Filed: 30 Dec 22
Utility
c6qaj35n2izlrspc493z3dc026koq83ew8h71y6rk ky0qg4
13 Jul 23
Disclosed herein are methods, compositions, systems, and kits related to functional testing of soluble polypeptides in a single-cell format.
Brandon DeKosky, Matias F. Gutierrez, Chengyu Chung, Ahmed Fahad, Nicoleen Boyle, Shuyan Jin
Filed: 11 Nov 22
Utility
iap58z8653oynxzrmw qb
11 Jul 23
Provided herein are branched poly(beta-amino esters) (PBAE) useful as vehicles for the delivery of therapeutic agents, such as nucleic acids.
Daniel Griffith Anderson, Kevin John Kauffman, James C. Kaczmarek, Asha Kumari Patel
Filed: 7 Sep 22
Utility
qwaia0veutjc9com7l0pexouwavowl43j3bigqk0g955upd
11 Jul 23
Crystal nucleation, and associated articles, systems, and methods, are generally described.
Kripa K. Varanasi, Henri-Louis Girard, Caroline McCue
Filed: 15 Oct 20
Utility
cb0h3w0vbyvyc1tiu4uqbbfvxrzusvfi3jkb02qcmxk2gwox6q4qr
11 Jul 23
Engineered Streptococcus canis Cas9 (ScCas9) variants include an ScCas9 protein with its PID being the PID amino acid composition of Streptococcus pyogenes Cas9 (SpCas9)-NG, an ScCas9 protein having a threonine-to-lysine substitution mutation at position 1227 in its amino acid sequence (Sc+), and an ScCas9 protein having a threonine-to-lysine substitution mutation at position 1227 and a substitution of residues ADKKLRKRSGKLATE [SEQ ID No. 4] in position 365-379 in the ScCas9 open reading frame (Sc++).
Pranam Chatterjee, Noah Michael Jakimo, Joseph M. Jacobson
Filed: 30 Jun 22
Utility
wbjomsy 3c4d1k3zbixikep5gmzm6ylva7ynx8ktc5ddxg2uurtyz1i
11 Jul 23
Swept-source Raman spectroscopy uses a tunable laser and a fixed-wavelength detector instead of a spectrometer or interferometer to perform Raman spectroscopy with the throughput advantage of Fourier transform Raman spectroscopy without bulky optics or moving mirrors.
Rajeev J. Ram, Amir H. Atabaki, Nili Persits, Jaehwan Kim
Filed: 1 Jun 21
Utility
tjt7f116hywrtmvqocuv4nriulmfwido
11 Jul 23
The present disclosure is directed to rheometric fixtures for making rheological measurements of yield stress fluids.
Crystal Elaine Owens, Gareth H. McKinley, Anastasios John Hart
Filed: 15 Oct 20
Utility
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11 Jul 23
Corona Phase Molecular Recognition (CoPhMoRe) utilizing a template heteropolymer adsorbed onto and templated by a nanoparticle surface to recognize a specific target analyte can be used for macromolecular analytes, including proteins.
Michael Strano, Michael Lee, Naveed Bakh, Song Wang
Filed: 4 May 20
Utility
tvmetzhsqmtr6psu08k9qnyshjwez3w4fgom6bsf502phxpp dcjt3ql2
11 Jul 23
An analog computing system with coupled non-linear oscillators can solve complex combinatorial optimization problems using the weighted Ising model.
Jeffrey Chou, Suraj Deepak Bramhavar, Siddhartha Ghosh, William Herzog
Filed: 27 Mar 20