3525 patents
Page 24 of 177
Utility
Systems, Methods, and Compositions for Site-specific Genetic Engineering Using Programmable Addition Via Site-specific Targeting Elements (Paste)
4 May 23
This disclosure provides systems, methods, and compositions for site-specific genetic engineering using Programmable Addition via Site-Specific Targeting Elements (PASTE).
Omar Abudayyeh, Jonathan Gootenberg
Filed: 14 Dec 22
Utility
Anti-fouling Coatings and Associated Systems and Methods
4 May 23
Anti-fouling coatings and associated systems and methods are generally described.
Michael Short, Bilge Yildiz, Max Carlson, Cigdem Toparli, Minh Dinh
Filed: 9 Mar 21
Utility
orx22dkio0yjcy0b4uoz1ze5sc0ksx7oj5b6by903jfv
4 May 23
A method for removing organic or inorganic micropollutants from aqueous solutions includes adding a biomass of biomaterial to the solutions, the biomaterial being an active or inactive biological organism, such as a yeast, having affinity for biosorption (adsorption by the biomass)of an organic or inorganic micropollutant present in the solution at, or below, a parts-per-billion concentration, and controlling the pH and temperature of the solution, as well as contact time and agitation, to be within a range suitable for biosorption of the at micropollutant by the biomaterial.
Patritsia Maria Stathatou, Filippos Tourlomousis, Christos Edouardos Athanasiou, Andreas Mershin, Neil A. Gershenfeld
Filed: 8 Sep 22
Utility
41zrj8c1kf2bi4kvdbl52ijwkrmskn5dtj3kq9gunspkty21lqyeq
2 May 23
Enhanced cleaning of a fouled membrane is achieved via controlled deformation in a method wherein a feed composition, comprising a solvent and dissolved components, flows into a retentate side of a membrane module.
Omar Labban, Grace Goon, John H. Lienhard, Xuanhe Zhao
Filed: 12 Oct 20
Utility
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2 May 23
The present invention relates to polyhydroxylated benzophenone compounds useful in the treatment of neurodegenerative, neurological, psychiatric, and cognitive diseases, in particular those associated with a deficiency in HDAC1 deacetylase activity.
Li-Huei Tsai, Stephen J. Haggarty, Debasis Patnaik, Ping-Chieh Pao
Filed: 9 Dec 20
Utility
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2 May 23
Engineered or non-naturally occurring systems and compositions comprising a novel Cas12b and a guide molecule.
Feng Zhang, Jonathan Gootenberg, Omar Abudayyeh, Julia Joung, Alim Ladha, Han Altae-Tran, Guilhem Faure
Filed: 5 Jun 20
Utility
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27 Apr 23
Herein is provided a ferrous shape memory alloy (SMA) wire and processes for production of ferrous shape memory alloy wire that do not require crystallographic texturing processes to achieve superior superelastic and SMA wire properties.
EDWARD PANG, CHRISTOPHER A. SCHUH, WONSEOK CHOI
Filed: 2 Apr 21
Utility
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27 Apr 23
A microfluidic system for causing perturbations in a cell membrane, the system including a microfluidic channel defining a lumen and being configured such that a cell suspended in a buffer can pass therethrough, wherein the microfluidic channel includes a cell-deforming constriction, wherein a diameter of the constriction is a function of the diameter of the cell.
Armon R. Sharei, Andrea Adamo, Robert S. Langer, Klavs F. Jensen
Filed: 25 Oct 21
Utility
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27 Apr 23
Systems and methods for rapid diagnostics related to the use of CRISPR effector systems and optimized guide sequences for detection of coronavirus, including multiplex lateral flow diagnostic devices and methods of use, are provided.
Jonathan Gootenberg, Omar Abudayyeh, Julia Joung, Alim Ladha, Han Altae-Tran, Guilhem Faure, Feng Zhang
Filed: 12 Feb 21
Utility
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27 Apr 23
Systems and methods are provided for semi-automated, portable, ultrasound guided cannulation.
Laura J. Brattain, Anthony E. Samir, Brian A. Telfer, Matthew Johnson, Nancy DeLosa, Lars Gjesteby, Theodore T. Pierce, Joshua Werblin
Filed: 21 Oct 22
Utility
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27 Apr 23
Covalently modified alginate polymers, possessing enhanced biocompatibility and tailored physiochemical properties, as well as methods of making and use thereof, are disclosed herein.
Arturo J. Vegas, Minglin Ma, Kaitlin M. Bratlie, Daniel G. Anderson, Robert S. Langer
Filed: 20 May 22
Utility
i1oriaaw2lslvnpvv375onu9loi6lt5rldafbpd7q93xukoob
27 Apr 23
A metal-organic chalcogenolate (MOC) includes silver phenylselenolate functionalized with at least one functional group.
William A. Tisdale, Watcharaphol Paritmongkol, Tomoaki Sakurada
Filed: 25 Oct 21
Utility
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25 Apr 23
Provided herein is a lateral flow diagnostic device and methods of using thereof.
Feng Zhang, Jonathan Gootenberg, Omar Abudayyeh
Filed: 4 Oct 18
Utility
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25 Apr 23
A system and a method for controlling a system are described.
Haruhiko Harry Asada, Jacob Guggenheim
Filed: 23 Mar 20
Utility
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25 Apr 23
Provided herein include methods and compositions for analyzing nucleic acid in individual cells.
Jason Daniel Buenrostro, Sai Ma, Aviv Regev
Filed: 4 Feb 20
Utility
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25 Apr 23
The invention provides for systems, methods, and compositions for targeting nucleic acids.
Feng Zhang, Bernd Zetsche, Johnathan S. Gootenberg, Omar O. Abudayyeh, Ian Slaymaker
Filed: 17 Dec 21
Utility
ixblpp7tkaqcwuivdpg68iobzpyym8gbfrnfacfa8afm1b5poumdefh
25 Apr 23
Provided in one embodiment is a method, comprising: sintering a plurality of nanocrystalline particulates to form a nanocrystalline alloy, wherein at least some of the nanocrystalline particulates may include a non-equilibrium phase comprising a first metal material and a second metal material, and the first metal material may be soluble in the second metal material.
Christopher A. Schuh, Mansoo Park
Filed: 12 Aug 19
Utility
9i1g2ey7bfqc907w4399jo9re91bs0qppxlexa21cssfn1
25 Apr 23
Optical microcavity resonance measurements can have readout noise matching the fundamental limit set by thermal fluctuations in the cavity.
Jordan Goldstein, Christopher Louis Panuski, Dirk Robert Englund
Filed: 31 May 21
Utility
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25 Apr 23
Multi-phase electrochemical cells and related systems and methods are generally described.
Yet-Ming Chiang, Andres Badel, Fei Wang
Filed: 12 Feb 21
Utility
htuwovk1toy9dhghyjvza31v4
25 Apr 23
An optical device as described herein includes a host substrate fabricated from a dielectric material transparent in the Infrared range.
Hualiang Zhang, Jun Ding, Juejun Hu, Tian Gu, Hanyu Zheng
Filed: 28 Jun 18