3525 patents
Page 3 of 177
Utility
All-optical spatial light modulator
2 Jan 24
A spatial light modulator (SLM) comprised of a 2D array of optically-controlled semiconductor nanocavities can have a fast modulation rate, small pixel pitch, low pixel tuning energy, and millions of pixels.
Christopher Louis Panuski, Dirk Robert Englund
Filed: 29 Mar 21
Utility
Chemical and physical sensing with a reader and RFID tags
2 Jan 24
A method of detecting a stimulus can include detecting an output from a radio frequency identification tag including a sensor.
Timothy Manning Swager, Joseph Michael Azzarelli, Jens Bomholdt Ravnsbæk, Katherine Andrea Mirica
Filed: 17 Dec 18
Utility
Return Flow System for Ion Concentration Polarization (ICP)
28 Dec 23
A device for purifying and/or concentrating a first water stream containing ionic impurities includes a first and second ion exchange membrane and a first porous membrane.
Jongyoon Han, Junghyo Yoon
Filed: 1 Sep 23
Utility
Transmucosal Amphiphile-protein Conjugate Vaccine
28 Dec 23
What is disclosed is a vaccine comprising an immunogen conjugated to an albumin-binding polymer-lipid tail, wherein the vaccine is suitable for transmucosal (e.g, intranasal) administration.
Darrell J. Irvine, Brittany L. Hartwell
Filed: 6 Mar 23
Utility
Crosslinking Comonomers for High Performance Degradable Thermosets
28 Dec 23
Jeremiah A. Johnson, Peyton Shieh, Keith Husted
Filed: 9 Nov 21
Utility
Enhanced Crystal Nucleation
28 Dec 23
Crystal nucleation, and associated articles, systems, and methods, are generally described.
Kripa K. Varanasi, Henri-Louis Girard, Caroline McCue
Filed: 26 May 23
Utility
Digital Crispr-based Method for the Rapid Detection and Absolute Quantification of Nucleic Acids
28 Dec 23
The present invention relates to a digital CRISPR-based method for detecting and quantitating target nucleic acids in a sample comprising: forming a mixture comprising sample nucleic acids; isothermal amplification reaction reagents for amplifying one or more target nucleic acid sequences; partitioning the mixture into a plurality of compartments; incubating the partitioned mixture at a temperature for isothermal amplification and Cas effector cleavage of an amplified DNA strand, detecting a signal from cleavage of the non-target sequence, thereby detecting the one or more target sequences in the sample, and determining the copy number of the target nucleic acid based on a Poisson distribution of the proportion of positive-to-negative compartments.
Xiaolin Wu, Hanry Yu, Timothy Kuan-ta Lu
Filed: 28 Oct 21
Utility
Engineered Chimeric Antimicrobial Agents Against Gram-positive Bacteria
28 Dec 23
The present invention relates to chimeric bacteriophage lysins which can be used to sanitize surfaces, for the treatment of bacterial infections and/or for the selective treatment of body odor-causing bacteria.
Boon Chong GOH
Filed: 14 Nov 21
Utility
Variable Inverter/Rectifier/Transformer
28 Dec 23
Described is a hybrid electronic and magnetic structure that enables a transformer with fractional and reconfigurable effective turns ratios (e.g. 12:0.5, 12:2/3, 12:1, and 12:2) and hereinafter referred to as a Variable-Inverter-Rectifier-Transformer (VIRT).
David J. Perreault, Mike Kavian Ranjram, Intae Moon
Filed: 22 Jun 23
Utility
System for Legal Precedent Prediction & Related Techniques
28 Dec 23
Described is a system and technique for identifying passages of legal precedent and assembling arguments that use this precedent.
Robert Zev MAHARI, Alex Paul PENTLAND
Filed: 28 Jun 22
Utility
Methods for Identifying Drivers of Immune Responses Using Molecular Expression Signatures of Immunomodulating Agents
21 Dec 23
The present disclosure provides methods for determining signatures of immune responses to immunomodulating agents in cells and in tissues.
Nir Hacohen, Ang Cui
Filed: 4 Nov 21
Utility
Systems and Methods for Compact, Decentralized Desalination of Feedwater for Point-of-use Applications
21 Dec 23
Systems and methods for configuring compact desalination RO systems operable for point-of-use applications are disclosed herein.
Quantum J. WEI, Sahil Rajesh SHAH, Grace Bethea CONNORS
Filed: 30 Nov 21
Utility
Engineered Protein for Rapid, Efficient Capture of Pathogen-specific Antibodies
21 Dec 23
The present disclosure relates to proteins comprising a target-binding domain for detection of anti-SARS-CoV-2 antibodies, methods, compositions and kits thereof.
Hadley Sikes Johnson, Eric Alexander Miller, Seunghyeon Kim
Filed: 10 Nov 21
Utility
Hemostatic Nanoparticles for the Treatment of Non-compressible Hemorrhage and Internal Bleeding
21 Dec 23
An injectable nanoparticular formulation and method of use thereof for treating non-compressible hemorrhage or internal bleeding has been developed.
Paula T. Hammond Cunningham, Bradley D. Olsen, George Velmahos, Celestine Jia Huey Hong
Filed: 15 Feb 23
Utility
Programmable Gene Editing Using Guide Rna Pair
21 Dec 23
Provided herein are compositions, methods, and systems comprising a DNA binding nickase, a reverse transcriptase, an integration enzyme, and a guide RNA pair.
Omar Abudayyeh, Jonathan Gootenberg
Filed: 19 Apr 23
Utility
Methods and compositions for predicting and preventing relapse of acute lymphoblastic leukemia
19 Dec 23
Described in exemplary embodiments herein are methods, compositions, and kits for diagnosing, prognosing, monitoring, treating and/or preventing a hemopoietic malignancy and/or relapse thereof in a subject.
Alexander K. Shalek, Peter Winter, David Weinstock, Mark Murakami, Scott Manalis, Andrew Navia, Jennyfer Galvez-Reyes
Filed: 30 Oct 20
Utility
3-d printed devices formed with magnetic inks and methods of making graded index structures
19 Dec 23
A 3-D printed device comprising one or more structures, the structures comprising a plurality of magnetically responsive particles and one or more diblock or triblock copolymers; the diblock or triblock copolymers having an A-B, A-B-A, or A-B-C block-type structure in which the A-blocks and C-blocks are an aromatic-based polymer or an acrylate-based polymer and the B-blocks are an aliphatic-based polymer.
Theodore H. Fedynyshyn, Jennifer A. Lewis, Bradley P. Duncan
Filed: 1 May 20
Utility
Structure-guided chemical modification of guide RNA and its applications
19 Dec 23
The disclosure relates to compositions comprising and methods for chemical modification of single guide RNA (sgRNA), tracrRNA and/or crRNA used individually or in combination with one another or Cas system components.
Hao Yin, Daniel G. Anderson, Robert S. Langer
Filed: 3 Feb 17
Utility
Circular RNA for translation in eukaryotic cells
19 Dec 23
Methods and constructs for engineering circular RNA are disclosed.
Daniel G. Anderson, Robert Alexander Wesselhoeft, Piotr S. Kowalski
Filed: 23 Aug 22
Utility
Measuring representational motions in a medical context
19 Dec 23
A method includes receiving data representing graphomotor motion during a succession of executions of graphomotor diagnostic tasks performed in a medical context by a subject, processing the received data using a computer, including determining a first set of quantitative features from a first execution of a task by the subject, and determining a second set of quantitative features from a second execution of a task by the subject, determining one or more metrics based on a comparison to the successive executions, including using at least the first set of quantitative features and the second set of quantitative features to determine said metrics, and providing a diagnostic report associated with neurocognitive mechanisms underlying the subject's execution of the tasks based on the determined metrics.
Randall Davis, Dana L. Penney
Filed: 2 Feb 21