3525 patents
Page 7 of 177
Utility
Helitron Mediated Genetic Modification
23 Nov 23
Compositions, systems and methods for targeted gene modification, insertion and perturbation of gene transcripts and nucleic acid editing are provided.
Feng Zhang, Jonathan Strecker, David Li
Filed: 8 Oct 21
Utility
Methods and Reagent for Diagnosing Bipolar Disorder
23 Nov 23
A 200 bp section of the CPG2 promoter region is responsive to lithium treatment for bipolar disorder (BD).
Elly Nedivi, Baovi N Vo
Filed: 14 Sep 22
Utility
A Method Of Detecting an Analyte and Related Systems
23 Nov 23
There is provided a method of detecting an analyte in a sample, the method comprising: incubating said sample with a reporter agent to allow said reporter agent to bind to said analyte, if present, in said sample; applying the incubated sample to a cellulose substrate to allow said analyte that is bound to said reporter agent to be captured onto said cellulose substrate by a capture agent comprising a cellulose binding domain (CBD), wherein said capture agent is: (i) incubated with said sample prior to the applying step; and/or (ii) immobilised on said cellulose substrate prior to the applying step; and detecting a signal effected by the reporter agent to determine the presence or absence of said analyte.
Patthara Kongsuphol, Huan Jia, Hadley D. Sikes
Filed: 17 Sep 21
Utility
High-density cryogenic wiring for superconducting qubit control
21 Nov 23
A high density wiring system to transmit radio frequency (RF) signals to superconducting qubits disposed within a dilution refrigerator is disclosed.
John D. Cummings, John A. Rokosz, Kyle J. Thompson, Steven J. Weber
Filed: 19 Jan 22
Utility
Resistive switching devices containing lithium titanate, and associated systems and methods
21 Nov 23
Jennifer Rupp, Juan Carlos Gonzalez Rosillo
Filed: 21 Feb 20
Utility
Articles and methods for processing scrap aluminum
21 Nov 23
Articles and methods for processing aluminum are generally described.
Peter Godart
Filed: 2 Sep 21
Utility
Compositions and Methods for Enhanced Lentiviral Production
16 Nov 23
Described herein are engineered retroviral delivery vesicle generation compositions, systems, and methods to deliver a cargo to a cell.
Feng Zhang, Alim Ladha
Filed: 19 Mar 21
Utility
System and Method for Large Field of View, Single Cell Analysis
16 Nov 23
A method and system for medical imaging employs an excitation source configured to cause an object having a plurality of cells to at least one of emit, reflect, and fluoresce light.
Moungi G. Bawendi, Jorge M. Ferrer, W. David Lee, Lisa F. Marshall, David G. Kirsch
Filed: 24 Jul 23
Utility
Alternating Multi-source Vapor Transport Deposition
16 Nov 23
Disclosed are vapor transport deposition systems and methods for alternating sequential vapor transport deposition of multi-component perovskite thin-films.
Vladimir Bulovic, Maximilian Hoerantner
Filed: 2 Mar 23
Utility
Tracking Nociception Under Anesthesia Using a Multimodal Metric
16 Nov 23
Systems and methods for tracking sympathetic-driven arousal state (SDAS) including nociception under anesthesia is described herein.
Sandya Subramanian, Emery Brown, Riccardo Barbieri
Filed: 9 May 23
Utility
System And Methods For Vestibular Stimulation For Modulating Sleep
16 Nov 23
Described are systems, devices and methods that use vestibular stimulation to control and improve sleep.
Abhinandan JAIN, Pattie MAES
Filed: 12 May 23
Utility
Compositions and Methods of Use of Crispr-cas Systems In Nucleotide Repeat Disorders
16 Nov 23
The invention provides for delivery, engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of target sequences.
Feng ZHANG, Beverly DAVIDSON, Chie-Yu LIN, Edgardo RODRIGUEZ
Filed: 8 Feb 23
Utility
Systems and Methods for Formulating Material In a Data-driven Manner
16 Nov 23
Systems and methods for optimizing the formulation of materials are provided.
Michael J. Foshey, Timothy P. Erps, Mina Konakovic Lukovic, Wojciech Matusik, Wan Shou, Klaus Stoll, Bernhard Ulrich von Vacano, Hanns Hagen Goetzke
Filed: 24 Jul 23
Utility
Activatable Therapeutic Peptides and Uses Thereof
16 Nov 23
Disclosed herein are fusion protein, comprising (a) at least one X1 domain comprising a half-life extension compound, including but not limited to a half-life extension polypeptide; (b) at least one X2 domain comprising an anionic block; (c) at least one X3 domain comprising a linker susceptible to cleavage at a site of disease, including but not limited to a microbial infection site or tumor site; and (d) at least one X4 domain comprising a therapeutic peptide; wherein the at least one X1, X2, X3, and X4 domains are covalently linked, and each X4 domain is linked to an X3 domain without an intervening X1 or X2 domain; compositions containing such fusion proteins, and methods for their use.
Sangeeta N. BHATIA, Chayanon NGAMBENJAWONG
Filed: 10 Mar 23
Utility
Catalytic process for selective polyolefin hydrogenolysis
16 Nov 23
Yuriy ROMÁN, Julie RORRER, Guido ZICHITTELLA, Gregg Tyler BECKHAM
Filed: 10 May 23
Utility
Leaf Spring with High Resolution Stiffness Control
16 Nov 23
A variable stiffness leaf spring mechanism and method of locking parallel leaf springs allow for a wide range of stiffness settings in a low-mass package.
Hugh M. Herr, Emily Ann Rogers-Bradley
Filed: 8 Sep 21
Utility
Compositions and methods to increase muscular strength
14 Nov 23
Provided herein are methods and compositions for increasing muscle strength, and for treating muscle wasting disorders, muscle degenerative disease, or exercise-induced weakness, and cancer.
Vivek Sivathanu, Roger Dale Kamm
Filed: 2 Nov 18
Utility
Software and methods for controlling neural responses in deep brain regions
14 Nov 23
Techniques for non-invasively controlling targeted neural activity of a subject are provided herein.
James Dicarlo, Pouya Bashivan, Kohitij Kar
Filed: 30 Apr 20
Utility
Learning device, learning method, learning program, retrieval device, retrieval method, and retrieval program
14 Nov 23
A learning device calculates an image feature using a model (image encoder) that receives an image and outputs the image feature obtained by mapping the image into a latent space.
Yasunori Ohishi, Akisato Kimura, Takahito Kawanishi, Kunio Kashino, James R. Glass, David Harwath
Filed: 31 Mar 21
Utility
Molecule Selection Using Simulation and Ranking Based on Binding Matrices
9 Nov 23
A computer-implemented method calculates the affinity and templating ability of a molecule for a nanoporous host framework using a multi-factor index that uses simulation outcomes as component indices.
Rafael Gomez-Bombarelli, Daniel Schwalbe-Koda
Filed: 11 Jan 23