1919 patents
Page 20 of 96
Utility
Transparent, Anti-fog Tape or Film and Related Devices and Methods
22 Dec 22
The present disclosure generally relates to a stretchable anti-fogging tape (SAT) that can be applied to diverse transparent materials with varied curvatures for persistent fogging prevention.
Gang Chen, Xuanhe Zhao, Shaoting Lin, Yoichiro Tsurimaki
Filed: 6 Jun 22
Utility
Real-time G-protein Coupled Receptor (GPCR) Linked Bioluminescent Sensing of Biological Targets and Processes
22 Dec 22
The invention relates to compositions and methods for making and use of a real-time cellular sensor.
Frances Nargi, Scott Thomas Wick, Deepak Mishra
Filed: 21 Apr 22
Utility
Methods and Compositions for High-throughput Compressed Screening for Therapeutics
22 Dec 22
Described in certain example embodiments herein are systems, methods, and uses thereof for high-throughput in vitro evaluating multiple test compounds in parallel for biological or pharmacological functions.
Benjamin Mead, Conner Samuel Kummerlowe, Alexander K. Shalek
Filed: 23 Oct 20
Utility
Methods and Uses for Remotely Triggered Protease Activity Measurements
22 Dec 22
The present disclosure relates to methods and products associated with in vitro and in vivo protease activity measurements and enzyme profiling.
Sangeeta N. Bhatia, Gabriel A. Kwong, Piyush K. Jain, Jaideep S. Dudani, Simone Schurle
Filed: 20 Jul 22
Utility
Lithium Metal Batteries Having Anode-free Current Collectors
22 Dec 22
The invention comprises an anode-free lithium metal cell having an anode-side current collector composed of lithium, a lithium alloy or lithium-containing compound or a transition metal having a lithium or lithium alloy or lithium-containing compound surface coating, to provide a specific energy of the cell of 350 Wh/kg or greater.
Venkatasubramanian VISWANATHAN, Vikram PANDE, Yet-Ming CHIANG
Filed: 19 Aug 20
Utility
Rna-based Logic Circuits with Rna Binding Proteins, Aptamers and Small Molecules
15 Dec 22
Engineered synthetic RNA-based genetic circuits are provided that are regulated exclusively at the post-transcriptional level.
Ron Weiss, Liliana Wroblewska, Velia Siciliano, Tasuku Kitada, Maria Hottelet Foley, Katie Bodner, Hirohide Saito, Kei Endo, Darrell J. Irvine, Tyler Wagner, Jacob Becraft
Filed: 3 May 22
Utility
Growing Programmable Enzyme-functionalized and Sense-and-response Bacterial Cellulose Living Materials with Engineered Microbial Co-cultures
15 Dec 22
The disclosure provides compositions and methods for growing programmable enzyme-functionalized and sense-and-response bacterial cellulose living materials with engineered microbial co-cultures.
Timothy Kuan-Ta Lu, Tzu-Chieh Tang, Wolfgang Ott, Tom Ellis, Charles Gilbert
Filed: 21 Aug 20
Utility
Widely Tunable Compact Terahertz Gas Lasers
15 Dec 22
Disclosed is a laser system including a first laser and a second laser.
Paul Chevalier, Arman Amirzhan, Marco Piccardo, Fan Wang, Steven Glen Johnson, Henry O. Everitt, Federico CAPASSO
Filed: 12 Nov 20
Utility
Patient-matched Organoid Systems for Studying Cancer
15 Dec 22
In certain example embodiments, the invention provides a method of generating an ex vivo cell-based system comprising dissociating an original tissue sample obtained from a subject into a single cell population; determining an in vivo phenotype of the tissue sample by conducting single-cell RNA analysis on a first portion of the single cells; establishing an ex vivo cell-based system from a second portion of the single cells; and culturing the ex vivo cell-based system in a medium or conditions selected to maintain the in vivo phenotype.
Alexander K. Shalek, Peter Winter, Andrew Navia, Srivatsan Raghavan, William Hahn, Andrew Aguirre, Brian Wolpin, Jennyfer Galvez-Reyes
Filed: 26 Oct 20
Utility
Sequence-controlled Polymer Storage
15 Dec 22
Disclosed are compositions and methods relating to sequence-controlled storage objected.
James L. Banal, Mark Bathe, Joseph Berleant, Charles E. Leiserson, Tao Benjamin Schardl
Filed: 9 Jun 22
Utility
Metal-organic Framework on Gas Diffusion Electrode
15 Dec 22
An electrode with a gas diffusion electrode (GDE) layer and a metal-organic framework (MOF) layer.
Mircea Dinca, Ruperto Mariano
Filed: 31 May 22
Utility
Product and Methods Useful for Modulating and Evaluating Immune Responses
15 Dec 22
The present invention provides isolated immune cells, immune cell populations and compositions, as well as markers, marker signatures and molecular targets characterising the immune cells.
Alexandra-ChloƩ VILLANI, Rahul SATIJA, Aviv Regev, Nir HACOHEN
Filed: 17 Aug 17
Utility
Non-naturally Occurring Capsids for Delivery of Nucleic Acids And/or Proteins
8 Dec 22
Provided herein are non-naturally occurring self-assembling polypeptides for transferring nucleic acids and/or proteins to a cell, pharmaceutical compositions comprising such polypeptides, and methods for treatment comprising use of such compositions.
Feng Zhang, Serge Gueroussov
Filed: 25 Feb 22
Utility
Effective Intranasal Delivery to Brain
8 Dec 22
The present invention relates to a technique for effective intranasal delivery to the brain.
Chae Ok YUN, Soo Hwan LEE, Dayananda KASALA, Robert S LANGER
Filed: 6 Nov 20
Utility
Compositions and Methods for Delivering Cargo to a Target Cell
8 Dec 22
Provided herein are compositions, systems, and methods for delivering cargo to a target cell.
Feng Zhang, Michael Segel
Filed: 18 Sep 20
Utility
CRISPR-RELATED METHODS AND COMPOSITIONS WITH GOVERNING gRNAS
8 Dec 22
Disclosed herein are methods and compositions useful in targeting a payload to, or editing a target nucleic acid, where a governing gRNA molecule is used to target, optionally inactivate, a Cas9 molecule or a Cas9 molecule/gRNA complex.
Feng ZHANG, Deborah PALESTRANT, Beverly DAVIDSON, Jordi MATA-FINK, Edgardo RODRIGUEZ, Alexis BORISY
Filed: 14 Jun 22
Utility
Distillation of MSA Embeddings to Folded Protein Structures using Graph Transformers
8 Dec 22
An attention-based graph architecture that exploits MSA Transformer embeddings to directly produce models of three-dimensional folded structures from protein sequences includes a method and system for augmenting the protein sequence to obtain multiple sequence alignments, producing enriched individual and pairwise embeddings from the multiple sequence alignments using an MSA-Transformer, extracting relevant features and structure latent states from the enriched individual and pairwise embeddings for use by a downstream graph transformer, assigning individual and pairwise embeddings to nodes and edges, respectively, using the downstream graph transformer to operate on node representations through an attention-based mechanism that considers pairwise edge attributes to obtain final node encodings, and projecting the final node encodings to form the computer-modeled folded protein structure.
Pranam Chatterjee, Allan S Costa, Joseph M. Jacobson, Raghava Manvith Ponnapati
Filed: 2 Jun 22
Utility
Optimized Fuel Management System for Direct Injection Ethanol Enhancement of Gasoline Engines
8 Dec 22
Fuel management system for enhanced operation of a spark ignition gasoline engine.
Leslie Bromberg, Daniel R. Cohn, John B. Heywood
Filed: 13 Jun 22
Utility
Decoding Signals By Guessing Noise
8 Dec 22
Devices and methods described herein decode a sequence of coded symbols by guessing noise.
Muriel MEDARD, Kenneth R. DUFFY
Filed: 15 Aug 22
Utility
Biomaterial-based Compositions to Deliver Plant Growth Promoting Microbes
1 Dec 22
The use of biological fertilizer combined with microbes can be used instead of herbicides, pesticides and synthetic fertilizers.
Benedetto MARELLI, Augustine ZVINAVASHE
Filed: 21 Oct 20