1919 patents
Page 18 of 96
Utility
Compositions, Methods and Systems for the Delivery of Gene Editing Material to Cells
9 Feb 23
This disclosure provides compositions, methods, and systems comprising a papillomaviral delivery vehicle for the delivery of gene editing material to cells.
Omar Osama Abudayyeh, Jonathan S. Gootenberg
Filed: 17 Jun 22
Utility
Delivery, Use and Therapeutic Applications of the Crispr-cas Systems and Compositions for Genome Editing
2 Feb 23
The invention provides for delivery, engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of target sequences.
Le CONG, David Benjamin Turitz COX, Matthias HEIDENREICH, Randall Jeffrey PLATT, Lukasz SWIECH, Feng ZHANG
Filed: 3 Jun 22
Utility
Dispensing Device with Membrane Based Trigger
26 Jan 23
A device may be configured with a housing having a reservoir and an outlet separated by a heat rupturable membrane.
Carlo Giovanni Traverso, Graham Arrick, Torben Sebastian Last
Filed: 11 Dec 20
Utility
Als Treatment Method, Als Pharmaceutical Composition, and Als Diagnostic Method
26 Jan 23
An ALS treatment method includes administering to an ALS patient an inhibitor for a target A or a promoter for a target B.
Manolis KELLIS, Sergio Sebastian PINEDA, Myriam HEIMAN, Makoto TAMURA
Filed: 30 Jun 22
Utility
Streptococcus Canis Cas9 as a Genome Engineering Platform with Novel PAM Specificity
26 Jan 23
A Streptococcus canis Cas9 (ScCas9) ortholog and its engineered variants, possessing novel PAM specificity, is an addition to the family of CRISPR-Cas9 systems.
Joseph M. Jacobson, Noah Michael Jakimo, Pranam Chatterjee
Filed: 28 Feb 22
Utility
Titanium-containing Alloys and Associated Methods of Manufacture
26 Jan 23
Titanium-containing alloys are generally described.
Kathrin Graetz, Christopher A. Schuh
Filed: 29 Apr 22
Utility
Riboregulators and Methods of Use Thereof
26 Jan 23
This disclosure provides riboregulators specific for particular viruses or for particular human transcription factors.
Luis Ruben Soenksen Martinez, Nicolaas Angenent-Mari, Alexander S. Garruss, James J. Collins, George M. Church, Katherine Collins, Diogo M. Camacho
Filed: 11 Dec 20
Utility
Novel Type VI Crispr Enzymes and Systems
26 Jan 23
The present disclosure provides for systems, methods, and compositions for targeting nucleic acids.
Feng Zhang, Han Altae-Tran, Soumya Kannan
Filed: 18 Sep 20
Utility
Point-of-use Devices and Methods for Determining Rheological Properties of Samples
26 Jan 23
Apparatuses and methods designed to allow for on-site, on-demand measurement of rheological properties of a sample are disclosed.
Nicole Alejandra BUSTOS, Lydia BOUROUIBA
Filed: 13 Jul 22
Utility
Gas Injection System for Plasma Blackout Alleviation Studies
19 Jan 23
A test article described herein enables ground-based arc jet testing to investigate RF blackout mitigation using electrophilic gas injection upstream of an antenna.
Humberto L. Caldelas, II, Wesley Harris
Filed: 13 Jul 22
Utility
Drawn Polymer Fibers for Use In Thermal Applications
19 Jan 23
Drawn polymer fibers have internal channels running, at least partially, through the length of the fibers.
John G. BRISSON, Kyle J. THOMPSON, John CUMMINGS, Jacob Lazer ADAMS, Lauren CANTLEY
Filed: 14 Jul 21
Utility
Methods And Apparatus For Acoustic Backscatter Communication
12 Jan 23
A communication system may communicate by backscattered acoustic signals that propagate through a liquid or solid.
Junsu JANG, Fadel ADIB
Filed: 22 Aug 22
Utility
Injectable Hydrogels for Cell Delivery to the Vitreous
5 Jan 23
The present disclosure presents hydrogel compositions for use in the treatment of an ocular disorder (e.g., a retinal disease) and methods of treating an ocular disorder in a subject in need thereof with the hydrogel compositions.
Pierre A. Colombe, Deepti Singh, Myron Spector, Michael Young
Filed: 3 Dec 20
Utility
Cerebrospinal Fluid Space Draining Catheters
5 Jan 23
Ventricular catheters and their methods of use are disclosed.
Lydia Bourouiba, Sungkwon Lee, Thomas Heldt
Filed: 18 Nov 20
Utility
Genetic, Developmental and Micro-environmental Programs In Idh-mutant Gliomas, Compositions of Matter and Methods of Use Thereof
5 Jan 23
This invention relates generally to compositions and methods for identifying genes and gene networks that respond to, modulate, control or otherwise influence tumors and tissues, including cells and cell types of the tumors and tissues, and malignant, microenvironmental, or immunologic states of the tumor cells and tissues.
Bradley Bernstein, Itay Tirosh, Mario Suva, Aviv Regev, Orit Rozenblatt-Rosen, Andrew Venteicher
Filed: 25 Jan 17
Utility
Deployable Hydrogen Reactor
5 Jan 23
Systems and methods related to deployable hydrogen reactors are described.
Erik Limpaecher, Eric Morgan
Filed: 15 Apr 22
Utility
Actuatable Device for Pulsatile Drug Delivery
5 Jan 23
Delivery systems and their methods of use for delivering one or more therapeutic compounds to a user are described.
Carlo Giovanni Traverso, Jason Siu-Wei Li, Rebecca McManus, Seungho Lee, Adam Wentworth, Qianqian Wan
Filed: 4 Dec 20
Utility
Explainable Propaganda Detection
5 Jan 23
Explainable propaganda detection is provided by parsing each sentence of a plurality of sentences in an article for structural details; identifying, via a machine learning model, dimensional features across the plurality of sentences based on the structural details; identifying, via the machine learning model, a propagandizing tactic demonstrated in each sentence of the plurality of sentences based a covariance score to the propagandizing tactic and the plurality of dimensional features identified for a given sentence; and displaying, in a user interface that includes the article, propaganda labels corresponding to the propagandizing tactic identified for each sentence of the plurality of sentences.
Preslav I. Nakov, Giovanni Da San Martino, Seunghak Yu
Filed: 30 Jun 22
Utility
Systems and Methods for Predicting the Trajectory of a Moving Object
29 Dec 22
Systems and methods for predicting a trajectory of a moving object are disclosed herein.
Xin Huang, Igor Gilitschenski, Guy Rosman, Stephen G. McGill, JR., John Joseph Leonard, Ashkan Mohammadzadeh Jasour, Brian C. Williams
Filed: 1 Dec 21
Utility
Screening of Nucleic Acid Sequence Variations Via Random Loading of Optically-encoded Particles
29 Dec 22
Embodiments disclosed herein provide reagents and methods for high-throughput screening of nucleic acid sequence variations in nucleic acid containing specimens.
David Feldman, Daniel Sazer, Paul Blainey
Filed: 22 Aug 22