1919 patents
Page 18 of 96
Utility
Compositions, Methods and Systems for the Delivery of Gene Editing Material to Cells
9 Feb 23
This disclosure provides compositions, methods, and systems comprising a papillomaviral delivery vehicle for the delivery of gene editing material to cells.
Omar Osama Abudayyeh, Jonathan S. Gootenberg
Filed: 17 Jun 22
Utility
Delivery, Use and Therapeutic Applications of the Crispr-cas Systems and Compositions for Genome Editing
2 Feb 23
The invention provides for delivery, engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of target sequences.
Le CONG, David Benjamin Turitz COX, Matthias HEIDENREICH, Randall Jeffrey PLATT, Lukasz SWIECH, Feng ZHANG
Filed: 3 Jun 22
Utility
wfy351otoug5ukpsi66xt1vt0mcfo154gig1oww7uyx41fdtji7b
26 Jan 23
A device may be configured with a housing having a reservoir and an outlet separated by a heat rupturable membrane.
Carlo Giovanni Traverso, Graham Arrick, Torben Sebastian Last
Filed: 11 Dec 20
Utility
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26 Jan 23
A Streptococcus canis Cas9 (ScCas9) ortholog and its engineered variants, possessing novel PAM specificity, is an addition to the family of CRISPR-Cas9 systems.
Joseph M. Jacobson, Noah Michael Jakimo, Pranam Chatterjee
Filed: 28 Feb 22
Utility
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26 Jan 23
An ALS treatment method includes administering to an ALS patient an inhibitor for a target A or a promoter for a target B.
Manolis KELLIS, Sergio Sebastian PINEDA, Myriam HEIMAN, Makoto TAMURA
Filed: 30 Jun 22
Utility
g4j3rwfl8hfjwg2n7blieqq0fm3d1ysw40k
26 Jan 23
Titanium-containing alloys are generally described.
Kathrin Graetz, Christopher A. Schuh
Filed: 29 Apr 22
Utility
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26 Jan 23
This disclosure provides riboregulators specific for particular viruses or for particular human transcription factors.
Luis Ruben Soenksen Martinez, Nicolaas Angenent-Mari, Alexander S. Garruss, James J. Collins, George M. Church, Katherine Collins, Diogo M. Camacho
Filed: 11 Dec 20
Utility
rgwe3u0uecq9aigjkujl1z jqmux4hral8drhst0j1
26 Jan 23
The present disclosure provides for systems, methods, and compositions for targeting nucleic acids.
Feng Zhang, Han Altae-Tran, Soumya Kannan
Filed: 18 Sep 20
Utility
yu2m77dqx7hclfirt0krdwiv7vnzcf2yatkvjc
26 Jan 23
Apparatuses and methods designed to allow for on-site, on-demand measurement of rheological properties of a sample are disclosed.
Nicole Alejandra BUSTOS, Lydia BOUROUIBA
Filed: 13 Jul 22
Utility
04h5o75mvma7syr0k5duqs04si5l8
19 Jan 23
A test article described herein enables ground-based arc jet testing to investigate RF blackout mitigation using electrophilic gas injection upstream of an antenna.
Humberto L. Caldelas, II, Wesley Harris
Filed: 13 Jul 22
Utility
ekmxlet1wja73k4g618jkquhxt1a83gj
19 Jan 23
Drawn polymer fibers have internal channels running, at least partially, through the length of the fibers.
John G. BRISSON, Kyle J. THOMPSON, John CUMMINGS, Jacob Lazer ADAMS, Lauren CANTLEY
Filed: 14 Jul 21
Utility
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12 Jan 23
A communication system may communicate by backscattered acoustic signals that propagate through a liquid or solid.
Junsu JANG, Fadel ADIB
Filed: 22 Aug 22
Utility
isf1hioruw3zr7mszyi6fdu2fh1q8poccg
5 Jan 23
The present disclosure presents hydrogel compositions for use in the treatment of an ocular disorder (e.g., a retinal disease) and methods of treating an ocular disorder in a subject in need thereof with the hydrogel compositions.
Pierre A. Colombe, Deepti Singh, Myron Spector, Michael Young
Filed: 3 Dec 20
Utility
cls8c465dg6lqntjta8icl9ybkww24mcpios6fb01o7lsdhe2dmcba
5 Jan 23
Delivery systems and their methods of use for delivering one or more therapeutic compounds to a user are described.
Carlo Giovanni Traverso, Jason Siu-Wei Li, Rebecca McManus, Seungho Lee, Adam Wentworth, Qianqian Wan
Filed: 4 Dec 20
Utility
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5 Jan 23
This invention relates generally to compositions and methods for identifying genes and gene networks that respond to, modulate, control or otherwise influence tumors and tissues, including cells and cell types of the tumors and tissues, and malignant, microenvironmental, or immunologic states of the tumor cells and tissues.
Bradley Bernstein, Itay Tirosh, Mario Suva, Aviv Regev, Orit Rozenblatt-Rosen, Andrew Venteicher
Filed: 25 Jan 17
Utility
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5 Jan 23
Ventricular catheters and their methods of use are disclosed.
Lydia Bourouiba, Sungkwon Lee, Thomas Heldt
Filed: 18 Nov 20
Utility
eg6vl4piersmgrb5d7h9gokwnzrs6up2cqi9v70r 1daxgbs
5 Jan 23
Systems and methods related to deployable hydrogen reactors are described.
Erik Limpaecher, Eric Morgan
Filed: 15 Apr 22
Utility
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5 Jan 23
Explainable propaganda detection is provided by parsing each sentence of a plurality of sentences in an article for structural details; identifying, via a machine learning model, dimensional features across the plurality of sentences based on the structural details; identifying, via the machine learning model, a propagandizing tactic demonstrated in each sentence of the plurality of sentences based a covariance score to the propagandizing tactic and the plurality of dimensional features identified for a given sentence; and displaying, in a user interface that includes the article, propaganda labels corresponding to the propagandizing tactic identified for each sentence of the plurality of sentences.
Preslav I. Nakov, Giovanni Da San Martino, Seunghak Yu
Filed: 30 Jun 22
Utility
58kd14bjo4xy4d b6jxzvwydbbme7474nni27hnsorsgxb72rutyqno
29 Dec 22
Systems and methods for predicting a trajectory of a moving object are disclosed herein.
Xin Huang, Igor Gilitschenski, Guy Rosman, Stephen G. McGill, JR., John Joseph Leonard, Ashkan Mohammadzadeh Jasour, Brian C. Williams
Filed: 1 Dec 21
Utility
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29 Dec 22
The invention relates to methods for promoting fixed nitrogen from atmospheric nitrogen, and related products.
Christopher A. Voigt, Min-Hyung Ryu, Mi Ryoung Song
Filed: 26 Aug 22