1919 patents
Page 25 of 96
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Transplant Diagnostics Using Crispr-based Technology
8 Sep 22
Described herein are nucleic acid detection systems, devices, and kits having a CRISPR component comprising an effector protein and a guide RNA, and/or a polynucleotide encoding a guide RNA, that binds or hybridizes to a corresponding target molecule.
Leonardo V. Riella, James J. Collins, Michael M. Kaminski
Filed: 5 Aug 20
Utility
Solid Phase Peptide Synthesis Processes and Associated Systems
1 Sep 22
Systems and processes for performing solid phase peptide synthesis are generally described.
Mark David Simon, Bradley L. Pentelute, Andrea Adamo, Patrick Louis Heider, Klavs F. Jensen
Filed: 21 Dec 21
Utility
Gas Sensor Device Containing Lithium Garnet
1 Sep 22
An SOx sensor includes a lithium garnet electrolyte, a sensing electrode, a reference electrode, and a heating element.
Jennifer Lilia Rupp, Zachary Hood, Moran Balaish
Filed: 27 Dec 21
Utility
Soluble Multimeric Immunoglobulin-scaffold Based Fusion Proteins and Uses Thereof
1 Sep 22
The present disclosure provides soluble, multimeric fusion proteins that bind to a component of the MHC/TCR immune complex, wherein the fusion proteins comprise a soluble T cell receptor (TCR) or soluble Major Histocompatibility Complex (MHC) linked to an immunoglobulin framework by a multimerization domain.
Darrell J. IRVINE, Leyuan MA
Filed: 17 Jul 19
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Flexing Semiconductor Structures and Related Techniques
25 Aug 22
Aspects include a method of fabricating a semiconductor structure including providing a semiconductor layer, scribing the semiconductor layer to provide one or more scribe lines, disposing a flexible support layer on the semiconductor layer, and applying a force to the scribed semiconductor layer so as to induce cracks along the scribe lines.
Vladimir BULOVIC, Ryan ZIMMERMAN
Filed: 22 Jul 20
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Knowledge Graphs In Machine Learning Decision Optimization
25 Aug 22
Training a machine learning model can include receiving time series data.
Yada Zhu, Yang Zhang, Pin-Yu Chen, Rahul Mazumder, Shibal Ibrahim, Wenyu Chen
Filed: 24 Feb 21
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Polymer Electrolytes for Electrochemical Cells
25 Aug 22
The present disclosure provides solid-state electrolytes based on a borylated-polymers (e.g., borylated-polybutadiene).
Yang Shao-Horn, Jeremiah A. Johnson, Jeffrey Lopez, Teruhiko Saito, Megan Hill, Sipei Li
Filed: 18 Feb 22
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Thermogelling Nanoemulsions for Pharmaceutical Manufacturing
25 Aug 22
Compositions contain nanoparticles containing nanocrystals of hydrophobic therapeutic, diagnostic, prophylactic agents, or a combination thereof, encapsulated in thermogelling polymers, such as methyl cellulose.
Liang-Hsun Chen, Patrick S. Doyle
Filed: 21 Dec 21
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Self-Shielded High Frequency Inductor
18 Aug 22
In one aspect, described is a magnetic-core inductor design approach that leverages NiZn ferrites with low loss at RF, distributed gaps and field balancing to achieve improved performance eat tens of MHz and at hundreds of watts and above.
Roderick S. BAYLISS, III, David J. PERREAULT, Charles SULLIVAN, Rachel S. YANG, Alex J. HANSON
Filed: 18 Feb 22
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High Energy Density Redox Flow Device
18 Aug 22
Redox flow devices are described including a positive electrode current collector, a negative electrode current collector, and an ion-permeable membrane separating said positive and negative current collectors, positioned and arranged to define a positive electroactive zone and a negative electroactive zone; wherein at least one of said positive and negative electroactive zone comprises a flowable semi-solid composition comprising ion storage compound particles capable of taking up or releasing said ions during operation of the cell, and wherein the ion storage compound particles have a polydisperse size distribution in which the finest particles present in at least 5 vol % of the total volume, is at least a factor of 5 smaller than the largest particles present in at least 5 vol % of the total volume.
Yet-Ming CHIANG, William Craig CARTER, Mihai DUDUTA, Pimpa LIMTHONGKUL
Filed: 22 Apr 22
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Self-actuating Articles
18 Aug 22
Self-actuating articles including, for example, self-actuating needles and/or self-actuating biopsy punches, are generally provided.
Carlo Giovanni Traverso, Alex G. Abramson, Ester Caffarel Salvador, Niclas Roxhed, Minsoo Khang, Taylor Bensel, Robert S. Langer
Filed: 17 May 18
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Kinetic Sensing, Signal Generation, Feature Extraction, And Pattern Recognition For Control Of Autonomous Wearable Leg Devices
18 Aug 22
An autonomous wearable leg device employs an array of sensors embedded along a support area, whereby a controller can generate a controlling command and send a controlling command to a prosthetic, orthotic, exoskeletal or wearable component to thereby control the prosthetic, orthotic, exoskeletal or wearable component.
Hugh M. Herr, Roman Stolyarov, Luke M. Mooney, Cameron Taylor, Matthew Carney
Filed: 6 Jan 22
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Systems and Methods for Determining Cardiac Performance
18 Aug 22
The systems and methods described herein determine metrics of cardiac performance via a mechanical circulatory support device and use the cardiac performance to calibrate, control and deliver mechanical circulatory support for the heart.
Ahmad El Katerji, Qing Tan, Christian Moyer, Alexander Ship, Sonya Sanat Bhavsar, Noam Josephy, Elazer R. Edelman, Brian Yale Chang, Steven Keller
Filed: 2 May 22
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Engineered Adeno-associated Virus Capsids
18 Aug 22
Described herein are methods of generating engineered viral capsid variants.
Pardis SABETI, Mohammadsharif TABEBORDBAR, Simon YE
Filed: 30 Mar 22
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Treatment of Acid Gases Using Molten Alkali Metal Borates, and Associated Methods of Separation
18 Aug 22
The removal of acid gases (e.g., non-carbon dioxide acid gases) using sorbents that include salts in molten form, and related systems and methods, are generally described.
Trevor Alan Hatton, Takuya Harada, Cameron G. Halliday
Filed: 25 Feb 22
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Hydration-based Shape Memory Adhesive Materials and Methods of Making
18 Aug 22
A dry shape memory adhesive material for adhering a target surface in the presence of fluid and for providing tunable mechanical contraction of an adhered surface.
Xuanhe Zhao, Hyunwoo Yuk, Heejung Roh
Filed: 8 Feb 22
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System and Method for Estimating and Predicting Vehicle Trip Energy Consumption
18 Aug 22
A system for estimating or predicting energy consumption for a trip of a personal vehicle includes a user facing portion and a back-end portion.
Jessika E. Trancik, Zachary A. Needell, James McNerney
Filed: 5 May 22
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Humidity Initiated Gas (Hig) Sensors for Volatile Organic Compounds Sensing
11 Aug 22
Volatile organic compounds (VOCs) can be sensed using humidity-initiated gas (HIG) sensors.
Maxwell Robinson, Karen K. Gleason
Filed: 3 Feb 22
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Systems, Devices and Methods for Non-invasive Hematological Measurements
11 Aug 22
A system for non-invasive hematological measurements includes a platform to receive a body portion of a user and an imaging device to acquire a set of images of a capillary bed in the body portion.
Carlos CASTRO-GONZALEZ, Ian BUTTERWORTH, Aurelien BOURQUARD, Alvaro Sanchez FERRO, Jason TUCKER-SCHWARTZ, Alberto PABLO TRINIDAD, MARIA J. LEDESMA CARBAYO, Tom Vettenburg
Filed: 7 Feb 22
Utility
Metastasis Specific Splice Variants of Mena and Uses Thereof In Diagnosis, Prognosis and Treatment of Tumors
11 Aug 22
Methods and kits for diagnosis, prognosis and treatment of metastatic tumors are provided where the metastatic tumor is characterized by changes in expression of +++, ++ and/or 11a variants of Mena.
John S. Condeelis, Sumanta Goswami, Frank Gertler, Paola Nistico
Filed: 16 Sep 21