1919 patents
Page 29 of 96
Utility
Circular Rna Compositions and Methods
9 Jun 22
Circular RNA and transfer vehicles, along with related compositions and methods are described herein.
Alexander Wesselhoeft, Daniel G. Anderson, Shinichiro Fuse, Brian Goodman, Allen T. Horhota, Raffaella Squilloni
Filed: 10 Dec 21
Utility
Type VII Crispr Proteins and Systems
9 Jun 22
The present application provides systems, methods and compositions used for targeted gene modification, targeted insertion, perturbation of gene transcripts, and nucleic acid editing.
Feng Zhang, Han Altae-Tran
Filed: 18 Mar 20
Utility
3uoyghz4tu80m6qwmtfvsv1i4jrzq khkl40s
9 Jun 22
Self-righting articles, such as self-righting capsules for administration to a subject, are generally provided.
Carlo Giovanni Traverso, Alex G. Abramson, Ester Caffarel Salvador, Niclas Roxhed, Minsoo Khang, Taylor Bensel, Robert S. Langer
Filed: 8 Oct 21
Utility
gfcf2tp49q9gip51y4i64gd33nstl8vb ujmmt5x9entjsd5otd
9 Jun 22
Provided herein are engineered cells that comprising a chimeric antigen receptor comprising an extracellular target-binding moiety and an intracellular signaling domain; and secrets a heavy-chain antibody (VHH) or a VHH fusion protein.
Yushu J. Xie, Hidde L. Ploegh
Filed: 6 Mar 20
Utility
c1bblx1awjoqzmygr69r1kti2z3pw4
9 Jun 22
The disclosure describes poly(β-thioester) polymers and polymeric nanoparticles, pharmaceutical compositions comprising these materials, their use in the treatment of cancer and infectious disease, and machine learning methods for identifying and selecting them.
ROBERT LANGER, CARLO TRAVERSO, AMEYA KIRTANE, DANIEL REKER, LEWIS SCOTT JONES, HYUNJOON KIM, NETRA RAJESH
Filed: 31 Jul 20
Utility
10xa1pj4y78e2wr3rggsqrbzn1jp64pgfkp
9 Jun 22
In some aspects, a system comprises a computer hardware processor and a non-transitory computer-readable storage medium storing processor-executable instructions for receiving, from one or more sensors, sensor data relating to a robot; generating, using a statistical model, based on the sensor data, first control information for the robot to accomplish a task; transmitting, to the robot, the first control information for execution of the task; and receiving, from the robot, a result of execution of the task.
Daniela Rus, Jeffrey Lipton, Aidan Fay, Changhyun Choi
Filed: 25 Feb 22
Utility
oi9fzhoooq91wv6jzozop1apz9pzb0jrekgpi 2foksdcl
9 Jun 22
A fabrication method includes receiving information corresponding to a first pattern, receiving information corresponding to a second pattern, controlling an extruder to print a first semi-liquid material in the first pattern, and controlling the extruder to print a second semi-liquid material in the second pattern.
Nicolas A. LEE, Ramon WEBER, Joseph Henry KENNEDY, JR., Joshua VAN ZAK, Jorge DURO-ROYO, Neri OXMAN
Filed: 14 Sep 21
Utility
l9wxm5zytvlojmlrsfd6l673 6wm4ab
9 Jun 22
Techniques for detecting embolic information for a patient.
Thomas Heldt, Syed Muhammad Imaduddin, Kerri Larovere, Barry Kussman
Filed: 8 Apr 20
Utility
1dsn40kz9z8t7qhnwmo2fvn91ktkrofi9v1qq8c0rquup3cc84
9 Jun 22
The present disclosure relates to systems and method of determining transcriptomic profile from omics imaging data.
Aviv Regev, Eeshit Dhaval Vaishnav
Filed: 16 Dec 21
Utility
d643m11tyvpb4ymd1ri25g0l40iadcjcb8ydb bwd7n
9 Jun 22
Described are systems and techniques for extracting frequency and voltage harmonic transients corresponding to individual load events.
Steven B. LEEB, John K. NOWOCIN, Peter LINDAHL, Spencer C. SHABSHAB
Filed: 14 Feb 20
Utility
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2 Jun 22
The invention, in some aspects relates to compositions and methods for altering cell activity and function and the introduction and use of light-activated ion channels.
Nathan KLAPOETKE, Brian Yichiun CHOW, Edward BOYDEN, Gane KA-Shu WONG, Yongku Peter CHO
Filed: 10 Feb 22
Utility
w6d0kklmfvjfck6t7xf6bt8k37u1z8u atzcevusbi9773i074t6
2 Jun 22
A control system and method locates a partially or fully occluded target object in an area of interest.
Tara BOROUSHAKI, Fadel ADIB, Junshan LENG
Filed: 19 Nov 21
Utility
1mb9nwwuf0y461why33 r8
2 Jun 22
A trans-disciplinary system for cell-free biosynthesis includes a cell-free transcription-translation (TX-TL) tool and modular, generalizable microfluidic architectures.
Andreas Mershin, Vincent Noireaux, James Francis Pelletier, Neil A. Gershenfeld
Filed: 6 Oct 21
Utility
dusdb87yzawavjyy4h6b89y jcmcfne9wl20zsbmyj23t
2 Jun 22
In general, the present invention is directed to materials that when in use resist fouling on their surfaces.
Michael P. Short, Max B. Carlson
Filed: 15 Feb 22
Utility
ly8ao1rn0zcyr348r ai19bszd208it
2 Jun 22
The systems, devices, and methods presented herein use a heart pump to obtain measurements of cardiovascular function.
Elazer Edelman, Brian Chang, Noam Josephy, Sonya Sanat Bhavsar
Filed: 3 Nov 21
Utility
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2 Jun 22
Microfluidic devices with neuronal cells, muscle cells, and optionally other cell types co-cultured therein are provided.
Roger Dale Kamm, Tatsuya Osaki
Filed: 9 Apr 19
Utility
9wkzemyw78wcf9xvdopvvx0wvyeyrr3t3vuwi9058zhoh97372 ftb5yc
2 Jun 22
The invention relates to gene expression profiles and signatures of CAR T cells.
Angela Boroughs, Nemo Marjanovic, Aviv Regev, Marcela Maus, Tamara Ouspenskaia
Filed: 29 Oct 19
Utility
nkxw3fu1jycwu bnlopebw4ovhxhsscsojkxfygseers5zpp
2 Jun 22
Photo-detectors disclosed include at least one of a thin film or a heterostructure of photo-sensitive material and a pair of Ohmic contacts coupled to the at least one of the thin film or the heterostructure.
Svetlana V. Boriskina, Bruno Lorenzi, Gang Chen, Yoichiro Tsurimaki
Filed: 31 Aug 21
Utility
244iqnvmpsva3u wx2hhm4ztoqpzdjfg
26 May 22
A fluid dynamic valve passively allows fluid flow out of a moving stream in one flow direction and not in the reverse.
Kyle THOMPSON, Gary A. SHAW, Andrew M. SIEGEL, Lawrence M. CANDELL
Filed: 29 Nov 21
Utility
079vaprq4b44wxrckx0sr69gomdd7cc1gfreans
26 May 22
An ankle-foot prosthesis comprises a foot structure having a foot keel leaf spring, a heel leaf spring, and an upper J leaf spring above the keel leaf spring.
Hugh M. Herr, Matthew Lawrence Handford, Christopher Charles Williams, Matthew Eli Carney, Daniel Visan Levine
Filed: 19 Nov 21