1919 patents
Page 30 of 96
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Control of Nitrogen Fixation In Rhizobia That Associate with Cereals
26 May 22
Disclosed herein are engineered rhizobia having nif clusters that enable the fixation of nitrogen under free-living conditions, as well as ammonium and oxygen tolerant nitrogen fixation under free-living conditions.
Christopher A. Voigt, Min-Hyung Ryu
Filed: 19 Mar 20
Utility
CPF1 Complexes with Reduced Indel Activity
26 May 22
The invention provides for systems, methods, and compositions for targeting nucleic acids.
Feng Zhang, Bernd Zetsche, Winston YAN, Neville Espi Sanjana, Sara Jones
Filed: 7 Feb 22
Utility
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26 May 22
Applications of a Streptococcus Cas9 ortholog from Streptococcus macacae (Smac Cas9), possessing minimal adenine-rich PAM specificity, include an isolated Streptococcus macacae Cas9 protein or transgene expression thereof, a CRISPR-associated DNA endonuclease with PAM interacting domain amino acid sequences that are at least 80% identical to that of the isolated Streptococcus macacae Cas9 protein, and an isolated, engineered Streptococcus pyogenes Cas9 (Spy Cas9) protein with a PID as either the PID amino acid composition of the isolated Streptococcus macacae Cas9 (Smac Cas9) protein or of a CRISPR-associated DNA endonuclease with PID amino acid sequences that are at least 80% identical to that of the isolated Streptococcus macacae Cas9 protein.
Pranam Chatterjee, Noah Michael Jakimo, Joseph M Jacobson
Filed: 6 May 19
Utility
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26 May 22
A programmable modular protein architecture for RNA binding comprises a set of modules, derived from RNA-binding protein Pumilio, that can be concatenated into chains of varying composition and length.
Edward S. Boyden, Katarzyna P. Adamala, Daniel Alberto Martin-Alarcon
Filed: 9 Feb 22
Utility
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26 May 22
Amplitude-modulated (AM) signals spanning a spatial wide area can be efficiently detected using a slowly scanning optical system.
Kenneth SCHULTZ
Filed: 26 Feb 20
Utility
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12 May 22
Articles, systems, and methods for rapid administration and active pharmaceutical compositions to subjects exposed to radiation and/or toxins are provided by this disclosure.
Hen-Wei Huang, James Byrne, Carlo Giovanni Traverso
Filed: 9 Sep 21
Utility
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12 May 22
The subject matter disclosed herein is generally directed to modulation of Th17 differentiation and pathogenicity by use of metabolic targets.
Aviv Regev, Chao Wang, Vijay K. Kuchroo, Nir Yosef, Allon Wagner, Johannes Fessler
Filed: 18 Mar 20
Utility
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12 May 22
Chemical reaction devices involving acid and/or base, and related systems and methods, are generally described.
Yet-Ming Chiang, Leah Ellis, Andres Badel, Isaac W. Metcalf
Filed: 13 Mar 20
Utility
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12 May 22
The present invention provides novel compositions and methods based on the discovery of the mechanisms and gene expression programs associated with homeostatic ILC2s and proinflammatory ILC2s that drive tissue inflammation.
Aviv Regev, Heping Xu, Jiarui Ding, Ramnik Xavier
Filed: 13 Mar 20
Utility
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12 May 22
Synthetic polymers, e.g., synthetic heparin mimetics, are provided, including hydrogel compositions incorporating the synthetic polymers.
Christopher S. Chen, Sangeeta N. Bhatia, Linqing Li, Jinling Yang, Jeroen Eyckmans
Filed: 14 Jul 21
Utility
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12 May 22
Described is a spacecraft locker configured be deployed in outer space and configured to assemble satellites (e.g., CubeSats) within it and deploy them in outer space.
Ezinne UZO-OKORO, Kerri L. CAHOY
Filed: 10 Nov 21
Utility
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12 May 22
This disclosure provides systems, methods, and compositions for site-specific genetic engineering using Programmable Addition via Site-Specific Targeting Elements (PASTE).
Omar Abudayyeh, Jonathan Gootenberg
Filed: 21 Oct 21
Utility
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12 May 22
An evaporatively cooled device and a system including the same.
Kin Chung FONG, Dirk Robert Englund
Filed: 11 Aug 21
Utility
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12 May 22
To improve actual labels that are produced by a black box computer classifier system from inputs, identify, using an environment-aware predictor and an environment-agnostic predictor, a subset of the inputs.
Shiyu Chang, Yang Zhang, Mo Yu, Tommi S. Jaakkola
Filed: 11 Nov 20
Utility
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12 May 22
Described are systems and techniques for extracting frequency and voltage harmonic transients corresponding to individual load events.
Steven B. LEEB, John K. NOWOCIN, Peter LINDAHL, Spencer SHABSHAB
Filed: 14 Feb 20
Utility
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5 May 22
Compositions and methods of making compositions for additive manufacturing of composite powders including metal ceramic alloyed material is described.
Ethan PARSONS
Filed: 5 Nov 21
Utility
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5 May 22
A heavy metal capture composition, devices including the composition, and a method of reducing heavy metal contamination in the environment is described.
Moungi BAWENDI, Vladimir BULOVIC, Richard SWARTWOUT, Nicole MOODY
Filed: 22 Feb 20
Utility
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5 May 22
The invention provides for systems, methods, and compositions for manipulation of sequences and/or activities of target sequences.
Feng Zhang, David Benjamin Turitz Cox, Luciano Marraffini, David Olivier Bikard, Wenyan Jiang, Neville Espi Sanjana
Filed: 18 Oct 21
Utility
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5 May 22
Spark ignition engine operation at higher RPM so as to reduce alcohol requirements in high efficiency alcohol enhanced gasoline engines is disclosed.
Daniel R. Cohn, Leslie Bromberg
Filed: 12 Jan 22
Utility
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5 May 22
Systems and methods for flowing particles, such as biological entities, in a fluidic channel(s) are generally provided.
Robert J. Kimmerling, Nicholas L. Calistri, Scott R. Manalis, Selim Olcum, Mark M. Stevens
Filed: 7 Oct 21