1252 patents
Page 2 of 63
Utility
Miniaturized, light-adaptive, wireless dosimeter systems for autonomous monitoring of electromagnetic radiation exposure and applications of same
2 Jan 24
A system for measuring a radiant exposure of electromagnetic radiation includes an accumulation detection module having a detector and configured to continuously monitor an electromagnetic radiation received by the detector; and an adaptive circuit configured to periodically interrogate the accumulation detection module; adjust a frequency of interrogation of the accumulation detection module based on an intensity of the electromagnetic radiation received by the detector; and autonomously transmit information related to an amount of the electromagnetic radiation received by the detector to a remote device.
Kyeongha Kwon, Seung Yun Heo, Anthony R. Banks, John A. Rogers
Filed: 2 Jul 20
Utility
Hydrophobic Drugs In Organic Core High Density Lipoprotein (HDL) Nanoparticles
28 Dec 23
Disclosed herein are high-density lipoprotein-like nanoparticles (HDL-NP) having a soft material core (e.g., a lipid-conjugated inorganic core) associated with hydrophobic therapeutic agents.
Stephen E. Henrich, Jonathan S. Rink, Adam Y. Lin, C. Shad Thaxton, Leo I. Gordon, Sonbinh T. Nguyen, Steven T. Rosen, David Horne, Xu Hannah Zhang
Filed: 22 Oct 21
Utility
Ion-based Methods for Stabilizing and Improving Porous Metal-organic Framework (Mof) Materials for Water Harvesting from Air and Related Applications
28 Dec 23
Metal Organic Frameworks (MOFs), methods of using the MOFs for harvesting water from air, and methods of making the MOFs are provided.
Joseph T. Hupp, Jian Liu, Zhiyong Lu
Filed: 9 Nov 21
Utility
Hierarchical Nanoporous Diamondoid Superstructure
28 Dec 23
Disclosed herein are compositions, supramolecular assemblies, crystalline compositions, and methods of making and using the same.
Qing-Hui Guo, James Fraser Stoddart
Filed: 12 Sep 23
Utility
Systems and Methods for Quantifying Patient Improvement Through Artificial Intelligence
28 Dec 23
Examples of a system and methods for quantifying patient improvement via artificial intelligence are disclosed.
Stephen A. Antos, Konrad P. Kording, Vivek Sagar
Filed: 31 Jan 22
Utility
Systems and Methods for Dieless Composite Forming
21 Dec 23
Knitmorphs and methods of knitmophing include knitting one or more yarn materials into knitted structure having a first shape.
Sangram Keshari Rout, Jian Cao, Marisa Ravena Bisram
Filed: 14 Apr 23
Utility
Melanin Hair Dye with Thickeners
21 Dec 23
Included herein are methods and materials for nontoxic, biocompatible, optionally metal-free, tunable, and long-lasting coloration of human hair.
Nathan C. GIANNESCHI, Zofia Elzbieta SIWICKA
Filed: 21 Jun 23
Utility
Terlipressin-octadecanedioic Acid Conjugate for Vasoconstrictive Therapy
14 Dec 23
In an aspect, disclosed herein is a compound characterized by formula (FX1): A1-X1—X2-A2 (FX1); wherein: A1 is a carboxylic acid group, a carboxylate anion, or a carboxylate ester, X1 is a substituted or unsubstituted and saturated or unsaturated C1-C50 aliphatic group; X2 is a linker group selected from the group consisting of a direct bond, an organic group, -0-, —S—, —S(═O)—, —S(═O)2—, —S—S—, —N═, ═N—, —N(H)—, —N═N—N(H)—, —N(H)—N═N—, —N(OH)—, —N(═O)—, and any combination thereof; and A2 is a peptide, the peptide being terlipressin or a substituted or unsubstituted derivative, a substituted or unsubstituted natural or synthetic analogue, a substituted or unsubstituted variant, a substituted or unsubstituted isomer, or a substituted or unsubstituted fragment of terlipressin.
Or BERGER, Wonmin CHOI, Nathan C. GIANNESCHI, Daniel BATLLE
Filed: 17 Dec 20
Utility
Wireless Probes for Monitoring Blood Flow In Biological Tissue
14 Dec 23
A wearable probe includes a sensor module and a control module.
Mitchell Pet, Matthew MacEwan, John Rogers, Changsheng Wu, Di Lu, Wubin Bai, Hexia Guo, Shuo Li, Hany Arafa
Filed: 22 Oct 21
Utility
Proteolysis-targeting chimeric molecules (PROTACs) that induce degradation of indoleamine 2,3-dioxygenase (IDO) protein
12 Dec 23
Disclosed are proteolysis-targeting chimeric molecules (PROTACs) that induce degradation of IDO protein.
Gary E. Schiltz, Derek A. Wainwright
Filed: 2 Jul 21
Utility
Catalysts and methods for enantioselective conjugate addition of amines to unsaturated electrophiles
12 Dec 23
Disclosed are complexes and methods of using the complexes as catalysts for addition of amines to unsaturated electrophiles, as well as novel compounds produced by the disclosed complexes and methods.
Karl A. Scheidt, Brice Uno
Filed: 21 Sep 20
Utility
Simultaneous estimation of cochlear and efferent activity
12 Dec 23
The present disclosure describes systems and methods to evaluate auditory efferent function by exposing a patient to short-duration acoustic click stimuli to generate a click-evoked otoacoustic emission (CEOAE) occurring in each ear of the patient, and in response to exposing the patient to click stimuli, concurrently sampling outer hair cell activity (OHC) and medial olivocochlear reflex (MOCR; efferents) in each ear of the patient, monitoring the middle ear muscle reflex (MEMR) in each ear of the patient, and measuring a change in cochlear activity in the patient based on the CEOAE, MOCR, and MEMR of each ear of the patient.
Sriram Boothalingam, Sumitrajit Dhar
Filed: 30 Apr 19
Utility
Methods for forming stereospecific, polar functionalized polypropylene
12 Dec 23
Methods for forming polar-functionalized isotactic and syndiotactic polypropylenes are provided, including amino-functionalized polypropylene.
Tobin J. Marks, Minglu Huang, Yanshan Gao
Filed: 4 Dec 20
Utility
Cobalt-substituted perovskite compounds for solid oxide electrochemical cells
12 Dec 23
Oxygen electrodes are provided, comprising a perovskite compound having Formula (I), Sr(Ti1-xFex-yCoy)O3-δwherein 0.90≥x≥0.40 and 0.02≥y≥0.30.
Shan-Lin Zhang, Scott A. Barnett, Matthew Lu
Filed: 1 Mar 19
Utility
Use of Nucleotide Synthesis Inhibitors for Targeted Therapy In MLL3/4 Compass Mutant Cancer
7 Dec 23
Disclosed herein are methods and compositions for treating a subject comprising the administration of an effective amount of a nucleotide synthesis inhibitor to a subject in need of treatment for a MLL3/4 COMPASS deficient cancer or a MLL3/4 loss of function mutation.
Ali Shilatifard, Zibo Zhao
Filed: 2 Jun 23
Utility
Use of Reelin for Treating Cardiac Diseases
7 Dec 23
Disclosed herein are compositions and methods useful for treating diseases, conditions and injuries of the heart, and/or improving cardiac function in a subject in need thereof.
Guillermo Oliver, Xiaolei Liu
Filed: 14 Oct 21
Utility
Electrical Write/read of High-information-density Magnetic Thin Film
7 Dec 23
According to certain aspects of the present disclosure, a device is provided.
Matthew A. Grayson, Pedram Khalili-Amiri, Chulin Wang, Claire Cecelia Onsager, Sevde Nur Arpaci, Victor Lopez Dominguez
Filed: 1 Jun 23
Utility
Battery-free Unmanned Aerial Vehicle
7 Dec 23
Unmanned aerial vehicles are provided.
Josiah David Hester, Rishabh Goel, VP Nguyen, Tien Pham
Filed: 1 Jun 23
Utility
Inhibitors of the Interaction Between TRIP8B and HCN Channels and Uses Thereof for Treating Neurological Diseases and Disorders
7 Dec 23
Disclosed herein are substituted phenyl compounds of formula I as defined herein that may be utilized as inhibitors of the interaction between the subunits of hyperpolarization-activated cyclic-nucleotide gated (HCN) channels, such as HCN1, and an auxiliary subunit of HCN channels which is the tetratricopeptide repeat-containing Rab8b-interacting protein (TRIP8b).
Gary E. Schiltz, Iredia David Iyamu, Ye Han, Dane M. Chetkovich, Kyle A. Lyman
Filed: 7 Jun 23
Utility
High-throughput Quantitative Measurement of Bulk Mechanical Properties of Soft Materials
7 Dec 23
Provided herein are systems and methods for carrying out high-throughput quantitative measurements of bulk mechanical properties of soft materials.
Muzhou Wang, Justin E. Griffith, Yusu Chen, Kenneth R. Shull
Filed: 7 Jun 23