1252 patents
Page 3 of 63
Utility
Portable Closed System for Culturing Cells Using Small Volumes of Capillary Blood
7 Dec 23
A portable, closed cell incubating cassette system and method including: an inlet to receive a volume of a liquid sample and fluidly connected to one or more incubating channels, each of which including one or more gates located in the one or more incubating channels, each of the gates having an open position and a closed position, wherein each of the gates when in the open position is configured to permit the sample to fluidly connect to a remaining portion of each of the incubating channels, and wherein each of the gates when in the closed position is configured to block the sample from fluidly connecting to the remaining portion of each of the incubating channels; and one or more sample incubation chambers each disposed in each of the incubating channels between the inlet and each of the gates.
Thomas McDade
Filed: 5 Jun 23
Utility
Integrated Process-structure-property Modeling Frameworks and Methods for Design Optimization And/or Performance Prediction of Material Systems and Applications of Same
7 Dec 23
An integrated process-structure-property modeling framework for design optimization and/or performance prediction of a material system includes a powder spreading model using a discrete element method (DEM) to generate a powder bed; a thermal-fluid flow model of the powder melting process to predict voids and temperature profile; a cellular automaton (CA) model to simulate grain growth based on the temperature profile; and a reduced-order micromechanics model to predict mechanical properties and fatigue resistance of resultant structures by resolving the voids and grains.
Wing Kam Liu, Jiaying Gao, Cheng Yu, Orion L. Kafka
Filed: 17 Jul 23
Utility
Intraoperative monitoring of neuromuscular function with soft, tissue-mounted wireless devices
5 Dec 23
The provided systems, methods and devices describe lightweight, wireless tissue monitoring devices that are capable of establishing conformal contact due to the flexibility or bendability of the device.
John A. Rogers, Michel Kliot, Roozbeh Ghaffari, YuHao Liu
Filed: 21 Dec 21
Utility
Structure-Function Relationships in the Development of Immunotherapeutic Agents
30 Nov 23
The present disclosure provides compositions and methods comprising spherical nucleic acid (SNA) components for use as immunotherapeutic agents.
Chad A. Mirkin, Shuya Wang, Bin Zhang, Kacper Skakuj
Filed: 28 Mar 23
Utility
Device for Detection of Cellular Stress
30 Nov 23
Disclosed is an assay for determining resistance in a target cell or tissue to a therapy associated with cellular stress using chemical microscopy and high-throughput single cell analysis to determine functional metabolic alteration, including determining metabolic reprogramming in a target cell or tissue to a therapy associated with cellular stress, and methods of using the assays.
Ji-Xin Cheng, Junjie Li, Yuying Tan, Daniela Matei, Guangyuan Zhao
Filed: 15 May 23
Utility
Polymorphisms for Predicting Treatment Response to Antipsychotic Drugs and Identifying New Drug Targets
30 Nov 23
Disclosed are methods, kits, and devices for diagnosing and treating psychiatric disorders and the symptoms thereof.
Jiang Li, Herbert Y. Meltzer
Filed: 2 Aug 23
Utility
Sparse Convolutional Neural Network Accelerator for 3D/4D Point-cloud Image Recognition
30 Nov 23
A sparse convolutional neural network (SCNN) accelerator for 3D and 4D point cloud image recognition and segmentation includes a hopping-index rule book method of coordinate management.
Jie Gu, Qiankai Cao
Filed: 24 May 23
Utility
Spherical Nucleic Acids with Dendritic Ligands
30 Nov 23
The present disclosure is directed to spherical nucleic acids (SNAs) comprising a nanoparticle core and an oligonucleotide dendron attached thereto.
Chad A. Mirkin, Katherine E. Bujold, Max Everett Distler
Filed: 24 Jul 23
Utility
Focal Adhesion Complex Proteins As a Diagnostic Marker for Podocytophathies
30 Nov 23
A system and method for identifying and/or predicting damage or disease of a patient's kidney podocyte layer, wherein the system includes a test kit configured to analyze the plasma or urine of the patient; and identify the presence of focal adhesion complex proteins, or anti-bodies associated with the focal adhesion complex proteins, in the plasma or urine, wherein the focal adhesion complex proteins comprise Integrin, Talin, Filamin, Vinculin, or other focal adhesion complex proteins.
Lorenzo Gallon, Robert V. Gerbasi
Filed: 11 Nov 21
Utility
Wireless surface mountable sensors and actuators
28 Nov 23
Provided herein are medical devices comprising a plurality of biologically interactive devices configured for interacting with a large area biological surface.
John A. Rogers, Seungyong Han, Sang Min Won, Jeonghyun Kim
Filed: 12 Jul 21
Utility
Peptide conjugated particles
28 Nov 23
The present invention provides compositions comprising peptide-coupled biodegradable poly(lactide-co-glycolide) (PLG) particles.
Lonnie D. Shea, Stephen D. Miller, Jonathan Woon Teck Yap, Daniel R. Getts, Derrick McCarthy
Filed: 17 Apr 20
Utility
Instruction driven dynamic clock management for deep pipeline and out-of-order operation of microprocessor using on-chip critical path messenger and elastic pipeline clocking
28 Nov 23
Systems and/or methods can include techniques to exploit dynamic timing slack on the chip.
Jie Gu, Russell E. Joseph
Filed: 18 Dec 19
Utility
Two-dimensional semiconductor based printable optoelectronic inks, fabricating methods and applications of same
28 Nov 23
Printable inks based on a 2D semiconductor, such as MoS2, and its applications in fully inkjet-printed optoelectronic devices are disclosed.
Mark C. Hersam, Jung-Woo Ted Seo, Jian Zhu
Filed: 27 Sep 19
Utility
Targeted PH Sensitive Liposomes
23 Nov 23
Disclosed herein are synthetic nanoparticles, pharmaceutical compositions, kits, or methods for treating and/or preventing cancer.
Leo I. Gordon, Dong-Hyun Kim, Shuo Yang, Wooram Park, Taehoon Sim
Filed: 4 Oct 21
Utility
In Vivo Detection of Surgical Materials
23 Nov 23
Provided herein are surgical materials detectable by multiple imaging modalities, including magnetic resonance imaging (MRI) and computerized tomography (CT).
Thomas J. Meade, Vinayak P. Dravid
Filed: 23 May 23
Utility
Methods for Growing Doped Cesium Lead Halides
23 Nov 23
Methods and devices for detecting incident radiation are provided.
Mercouri G. Kanatzidis, Yihui He
Filed: 10 Jul 23
Utility
Cryogenic solid state heat pump
21 Nov 23
Systems and/or methods can provide for solid-state refrigeration below 1 degree Kelvin.
Matthew Grayson
Filed: 1 May 20
Utility
Photocontrolled dynamic covalent linkers for polymer networks
21 Nov 23
Reversibly crosslinkable polymeric networks, including reversibly crosslinkable hydrogel networks are provided.
Julia A. Kalow, Joseph V. Accardo, Boyeong Kang
Filed: 15 Jun 22
Utility
Solid Acid Electrochemical Cells for the Production of Hydrogen
16 Nov 23
Electrochemical cells for the production of hydrogen from liquid fuels and methods of operating the cells to produce hydrogen and electricity are provided.
Dae-Kwang Lim, Austin Blake Plymill, Sossina M. Haile, Calum C.R. I. Chisholm, Strahinja Zecevic
Filed: 5 Oct 21
Utility
Method and System for Three-dimensional Scanning of Arbitrary Scenes
16 Nov 23
A three-dimensional (3D) imaging system includes a projector configured to illuminate a scene.
FLORIAN WILLOMITZER, Oliver Strider Cossairt
Filed: 8 May 23