140 patents
Page 3 of 7
Utility
Formulations of L-ornithine Phenylacetate
16 Jun 22
Some embodiments of the present application are directed to oral formulations of L-ornithine phenylacetate and methods of preparing the same.
Kenneth Ruettimann, Mark Coffin, James Bernstein, Gary Goodson, Laurene Wang
Filed: 22 Dec 21
Utility
Gas Delivery System
16 Jun 22
A gas delivery system is provided.
James Potenziano
Filed: 25 Mar 20
Utility
Compensating for Disruptions In Breathing Gas Flow Measurement
16 Jun 22
The present disclosure generally relates to systems and methods for delivery of therapeutic gas to patients, using techniques to compensate for disruptions in breathing gas flow measurement, such as when breathing gas flow measurement is unavailable or unreliable.
Jaron M. Acker, Craig R. Tolmie
Filed: 2 Mar 22
Utility
Intelligent Gas Source Management
2 Jun 22
Therapy gas delivery systems that provide run-time-to-empty information to a user of the system and methods for administering therapeutic gas to a patient.
Jaron M. Acker, Craig R. Tolmie, Robin Roehl, Jeffrey Schmidt, Jeff Milsap
Filed: 17 Feb 22
Utility
Apparatus and Method for Filtering Liquid Particles from Inspiratory Gas Flow of a Patient Breathing Circuit Affiliated with a Ventilator And/or Nitric Oxide Delivery System
26 May 22
The present disclosure relates to a filter apparatus for filtering liquid from a gas, the apparatus having a first housing having a gas inlet and a gas outlet; a first filter media disposed in the first housing; a second filter media disposed in the housing; and a second housing forming a first collection basin disposed in the flow path between the first filter media and the second filter media, so that a path is defined for the gas flowing from the inlet, through the first filter media, past the collection basin, through the second filter media, and to the outlet.
Scott I. Biba, John Falligant
Filed: 8 Feb 22
Utility
L-ornithine Phenyl Acetate and Methods of Making Thereof
26 May 22
Disclosed herein are forms of L-ornithine phenyl acetate and methods of making the same.
Keith Anderson, Jim Behling, Christine Henderson Dougan, Stephen William Watt, Peter Manini, Attilia Figini
Filed: 1 Nov 21
Utility
Method of Treating Patients with Hepatorenal Syndrome Type 1
12 May 22
The principles and embodiments of the present disclosure relate to methods for using terlipressin to treat a patient having impaired renal function associated with liver disease.
Khurram Jamil, Stephen Chris Pappas, Jim Potenziano
Filed: 28 Jan 22
Utility
Systems and methods for indicating lifetime of an NO
10 May 22
The principles and embodiments of the present invention relate to methods and systems for safely providing NO to a recipient for inhalation therapy.
Jaron Acker, Muhammad Asif, Craig Flanagan, Douglas Alan Greene, Sarah Jayne Ridley, Frank Kenneth Schweighardt, Lien-Lung Sheu
Filed: 26 Nov 19
Utility
Methods of Promoting Remyelination
14 Apr 22
The present disclosure is directed to methods of increasing remyelination in subjects in need thereof.
Dale Wright, Rick Fitch
Filed: 7 Jan 20
Utility
Administration and monitoring of nitric oxide in ex vivo fluids
5 Apr 22
Described are systems and methods for monitoring administration of nitric oxide (NO) to ex vivo fluids.
Jim Potenziano, Douglas R. Hansell, Jeff Griebel, Eddie Costa, Lisa Cooper, David William Newman
Filed: 21 Apr 17
Utility
Compensating for disruptions in breathing gas flow measurement
5 Apr 22
The present disclosure generally relates to systems and methods for delivery of therapeutic gas to patients, using techniques to compensate for disruptions in breathing gas flow measurement, such as when breathing gas flow measurement is unavailable or unreliable.
Jaron M. Acker, Craig R. Tolmie
Filed: 10 Oct 19
Utility
Intelligent gas source management
29 Mar 22
Therapy gas delivery systems that provide run-time-to-empty information to a user of the system and methods for administering therapeutic gas to a patient.
Jaron M. Acker, Craig R. Tolmie, Robin Roehl, Jeffrey Schmidt, Jeff Milsap
Filed: 20 Mar 20
Utility
Apparatus and method for filtering liquid particles from inspiratory gas flow of a patient breathing circuit affiliated with a ventilator and/or nitric oxide delivery system
22 Mar 22
The present disclosure relates to a filter apparatus for filtering liquid from a gas, the apparatus having a first housing having a gas inlet and a gas outlet; a first filter media disposed in the first housing; a second filter media disposed in the housing; and a second housing forming a first collection basin disposed in the flow path between the first filter media and the second filter media, so that a path is defined for the gas flowing from the inlet, through the first filter media, past the collection basin, through the second filter media, and to the outlet.
Scott I. Biba, John Falligant
Filed: 1 May 20
Utility
Processes for Preparing MORPHINAN-6-ONE Products with Low Levels of Alpha, Beta-unsaturated Ketone Compounds
17 Mar 22
The present invention generally relates to processes for preparing highly pure morphinan-6-one products.
Henry J. Buehler, William E. Dummitt, Anthony Mannino, Dennis C. Aubuchon, Hong Gu
Filed: 29 Nov 21
Utility
Enhanced Performance Verification Port for Therapeutic Gas Delivery
10 Mar 22
Therapy gas delivery systems that provide run-time-to-empty information to a user of the system and methods for administering therapeutic gas to a patient.
Jaron M. Acker, John C. Falligant, Jeff Milsap, Robin Roehl, Jeffrey Schmidt, Craig R. Tolmie
Filed: 12 Nov 21
Utility
Treatment of portal hypertension and restoration of liver function using L-ornithine phenylacetate
8 Mar 22
Disclosed herein are methods of treating and/or preventing portal hypertension and/or restoring liver function using L-ornithine phenylacetate.
Rajiv Jalan, Keith Anderson
Filed: 20 Nov 17
Utility
Method for Ex-vivo Expansion of Regulatory T Cells with Enhanced Suppressive Function for Clinical Application In Immune Mediated Diseases
24 Feb 22
The invention provides methods for the ex-vivo expansion of CD4+CD25+ Tregs.
Tinghua Cao, Li Li
Filed: 1 Nov 21
Utility
Devices And Methods For Engaging Indexed Valve And Pressurized Canister Assembly With Collar And For Linear Actuation By Plunger Assembly Into Fluid Communication With Device For Regulating Drug Delivery
10 Feb 22
A valve assembly comprising a housing and a valve, the valve being disposed within the housing, a first indexed member integral to the housing, the first indexed member adapted to be complementary to a second indexed member, and a radio frequency identification device adapted to communicate with a radio frequency receiver, the valve being configured to align with a canister, seal the canister and open in a single movement.
Frederick J. Montgomery, Duncan P. Bathe, Daniel J. Lee, Scott I. Biba, Todd J. Bakken
Filed: 25 Oct 21
Utility
Gas Sensor Module
3 Feb 22
A removable gas sensor module is provided for a therapeutic gas delivery device.
Jaron Acker, Peter James Clark, Cedric Assambo, Michael McAtamney, John Klaus, Robin Roehl
Filed: 3 Dec 19
Utility
Formulations of L-ornithine phenylacetate
11 Jan 22
Some embodiments of the present application are directed to oral formulations of L-ornithine phenylacetate and methods of using the same.
Laurene Wang, Stanley Bukofzer, Linda S. Grais
Filed: 11 Nov 16