140 patents
Page 5 of 7
Utility
Processes of making L-ornithine phenylacetate
20 Jul 21
Embodiments of the present disclosure are related to improved processes for making L-ornithine phenylacetate without using any silver salts or forming any L-ornithine intermediate salts, such as a benzoate salt.
Ludwig Pilsl, Georg Winkler, Frank Demartin, Vassil Elitzin
Filed: 7 May 18
Utility
Systems And Methods Of Administering A Pharmaceutical Gas To A Patient
15 Jul 21
Methods and systems for delivering a pharmaceutical gas to a patient.
Frederick J. Montgomery, Duncan P. Bathe
Filed: 29 Mar 21
Utility
Processing Blood
24 Jun 21
Methods (300), devices, and systems of processing blood are described.
David Peritt, Philip Wong, Janet Lesley MacPherson, Kevin Henrichsen, Geoffrey Phillip Symonds, Susan Pond
Filed: 15 Feb 21
Utility
Delayed sustained release pharmaceutical compositions
15 Jun 21
Delayed sustained release pharmaceutical compositions that provide therapeutic effects over extended periods of time (i.e., 14-16 hours).
Tsz Chung Lai, Alexander Brian Lippold, Rebecca Sue Walker, Jae Han Park
Filed: 7 Jun 18
Utility
Device And Method For Diffusing High Concentration NO With Inhalation Therapy Gas
13 May 21
Systems and methods of the present invention can enable high concentration NO to be delivered into ventilator breathing circuits, via a diffusing device, without generating undesirably large amounts of NO2.
John C. Falligant, Craig R. Tolmie
Filed: 18 Jan 21
Utility
Method of Treating Patients with Hepatorenal Syndrome Type 1 and Low Mean Arterial Pressure
6 May 21
The principles and embodiments of the present disclosure relate to methods of increasing survival of a patient having type 1 hepatorenal syndrome (HRS-1) and low mean arterial pressure (MAP).
Khurram Jamil, Stephen Chris Pappas, Peter Teuber
Filed: 29 Oct 20
Utility
Processing blood
9 Mar 21
Methods (300), devices, and systems of processing blood are described.
David Peritt, Philip Wong, Janet Lesley Macpherson, Kevin Henrichsen, Geoffrey Phillip Symonds, Susan Pond
Filed: 25 Oct 18
Utility
Preparation of Sufentanil Citrate and Sufentanil Base
4 Mar 21
Provided herein are processes for forming sufentanil citrate from sufentanil base.
George Helmut Klemm, Brian Orr, Joel McClenaghan
Filed: 6 Nov 20
Utility
Hydroxypropyl beta-cyclodextrin compositions and methods
2 Mar 21
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
Bernardus Nicolaas Machielse, Allan Darling
Filed: 4 Jun 19
Utility
Processing blood
23 Feb 21
Methods (300), devices, and systems of processing blood are described.
David Peritt, Philip Wong, Janet Lesley Macpherson, Kevin Henrichsen, Geoffrey Phillip Symonds, Susan Pond
Filed: 9 May 18
Utility
Process for preparing acylated amphetamine derivatives
23 Feb 21
Processes for preparing acetylated amphetamine derivatives and, in particular, processes for preparing L-lysine-D-amphetamine dimesylate from D-amphetamine salts.
Brian Orr, Kevin Roesch, Joel McClenaghan
Filed: 27 Nov 18
Utility
Cannula for minimizing dilution of dosing during nitric oxide delivery
16 Feb 21
Described are nasal cannulas that improve the precision of the delivered dose for nitric oxide therapy by reducing the dilution of nitric oxide.
Craig Flanagan, Simon Freed, John Klaus, Thomas Kohlmann, Martin D. Meglasson, Manesh Naidu, Parag Shah
Filed: 23 Oct 17
Utility
Breathing apparatus detection and purging
2 Feb 21
Described are methods for safer nitric oxide delivery, as well as apparatuses for performing these methods.
Jaron M. Acker, Thomas Kohlmann
Filed: 23 Jan 17
Utility
Preparation of sufentanil citrate and sufentanil base
26 Jan 21
Provided herein are processes for forming sufentanil citrate from sufentanil base.
George Helmut Klemm, Brian Orr, Joel McClenaghan
Filed: 22 Jan 19
Utility
Hydroxypropyl Beta-cyclodextrin Compositions and Methods
21 Jan 21
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
Bernardus Nicolaas Machielse, Allan Darling
Filed: 29 Sep 20
Utility
Systems and methods for intelligent gas source management and/or systems and methods for delivery of therapeutic gas and/or enhanced performance verification for therapeutic gas delivery
19 Jan 21
Therapy gas delivery systems that provide run-time-to-empty information to a user of the system and methods for administering therapeutic gas to a patient.
Jaron M. Acker, Craig R. Tolmie, Robin Roehl, Jeffrey Schmidt, Jeff Milsap
Filed: 12 Dec 18
Utility
Device and method for diffusing high concentration NO with inhalation therapy gas
19 Jan 21
Systems and methods of the present invention can enable high concentration NO to be delivered into ventilator breathing circuits, via a diffusing device, without generating undesirably large amounts of NO2.
John C. Falligant, Craig R. Tolmie
Filed: 30 Sep 16
Utility
Systems And Methods For Providing A Pulse Of A Therapeutic Gas With A Desired Flow Profile To Maximize Therapeutic Effectiveness
23 Dec 20
Described are systems and methods for providing a pulse of a therapeutic gas with a desired flow profile to maximize therapeutic effectiveness.
Thomas Kohlmann, John Klaus
Filed: 30 Aug 20
Utility
Abuse Deterrent Immediate Release Formulations Comprising Non-cellulose Polysaccharides
25 Nov 20
The present disclosure provides pharmaceutical compositions that provide immediate release of active ingredients and have abuse deterrent properties.
Alex Micka, Kai Feng, Tsz Chung Lai, Jonathan Gaik
Filed: 10 Aug 20
Utility
Methods to Increase Functional Capacity and Quality of Life In Bronchietasis Patients with Nontuberculous Mycobacteria
18 Nov 20
Provided herein are method of treating a patient with nontuberculous mycobacteria by administering nitric oxide to the patient for at least 100 days to increase functional capacity and quality of life of the patient.
James Potenziano, Christopher Miller
Filed: 14 May 20