195 patents
Utility
Method and system for assessing drug efficacy using multiple graph kernel fusion
9 Jan 24
Embodiments of the present systems and methods may provide techniques to predict the success or failure of a drug used for disease treatment.
Ophir Frieder, Hao-Ren Yao, Der-Chen Chang
Filed: 29 Jun 22
Utility
Quantitative auxiliary-free chirality sensing with a metal probe
2 Jan 24
The present invention relates to an analytical method that includes providing a sample potentially containing a chiral analyte that can exist in stereoisomeric forms, and providing a probe selected from the group consisting of metal salts.
Christian Wolf, Zeus A. O. De Los Santos, Ciaran Lynch
Filed: 11 Sep 19
Utility
Compositions and Methods for the Diagnosis and Treatment of Age-related Macular Degeneration
28 Dec 23
The present invention is related to diagnostic, treatment and compound screening methods related to dry age-related macular degeneration (dry AM D).
Nady Golestaneh
Filed: 22 Apr 23
Utility
Compositions and Methods for Enhancing T Cell Penetration of Tumors and Cancers
14 Dec 23
Provided are methods for enhancing anti-tumor and/or anti-cancer immunotherapies.
Allen Cato, Lynda Sutton, Jill P. Smith
Filed: 8 Nov 21
Utility
Specialized Computing Environment for Co-analysis of Proprietary Data
16 Nov 23
A specialized computing environment that includes hardware and data security features to enable competitive organizations to co-analyze proprietary data without revealing the underlying proprietary data to unauthorized users.
David Hartley, Ophir Frieder
Filed: 9 May 23
Utility
Assessing Diseases by Analyzing Gait Measurements
9 Nov 23
A gait analysis system, which includes a neural network with a recurrent neural network layer and a fully connected layer, that receives sensor data indicative of an individual's gait and outputs an assessment regarding the individual's health.
Gholam Motamedi, Ophir Frieder, Cristopher Flagg, Jian-Young Wu
Filed: 26 Jan 23
Utility
Metabolic biomarkers for memory loss
7 Nov 23
The present invention relates to methods of determining if a subject has an increased risk of suffering from memory impairment.
Howard J. Federoff, Massimo S. Fiandaca, Amrita K. Cheema, Mark E. Mapstone
Filed: 25 Jan 21
Utility
Stem Cell-like Memory T Cells and Uses Thereof
12 Oct 23
Provided herein are compositions comprising CD4+ stem cell like memory T (TSCM) cells and their uses in the treatment of cancer, infection and autoimmune disorders.
Samir N. KHLEIF, Vivek VERMA
Filed: 20 Aug 21
Utility
Radiation Mitigator and Method of Use Thereof
5 Oct 23
Milton L. Brown, Yali Kong, Courtney Houchen, Sripathi M. Sureban, Parthasarathy Chandrakesan
Filed: 8 Jun 23
Utility
Diverting jejunostomy tube
3 Oct 23
An enteral feeding device permitting diversion of gastrointestinal fluid from an afferent limb to an efferent limb of gastrointestinal tract in a subject is provided.
Emil Cohen
Filed: 29 Mar 19
Utility
Wearable Vibrotactile Speech Aid
28 Sep 23
A method for training vibrotactile speech perception in the absence of auditory speech can comprise selecting a first word, generating a first control signal configured to cause at least one vibrotactile transducer to vibrate against a person's body with a first vibration pattern based on the first word, sampling a second word, generating a second control signal configured to cause a vibrotactile transducer to vibrate against the person's body with a second vibration pattern based on the second word, and presenting a comparison between the first word and the second word to the person.
Patrick S. Malone, Maximilian Riesenhuber
Filed: 1 Jun 23
Utility
Targeting tumor cells with chemotherapeutic agents conjugated to anti-matriptase antibodies by in vivo cleavable linking moieties
12 Sep 23
The present invention relates to anti-matriptase antibodies and immunoconjugates of anti-matriptase antibodies with cytotoxic agents and the use thereof for killing or inhibiting the growth of matriptase-expressing cancer cells, such as those of multiple myeloma and breast cancers.
Siang-Yo Lin, Joseph R. Bertino, Chen-Yong Lin, Zoltan Szekely
Filed: 12 Mar 21
Utility
Detecting infection using surrogates
15 Aug 23
A triage system that determines whether a user is likely to have contracted a disease based on sensor data received from a user device (e.g., a smartphone or activity tracker).
Howard Federoff, Ophir Frieder
Filed: 19 Aug 21
Utility
Combination Therapy of Artemisinin-related Compounds and Histone Deacetylase Inhibitors for Treatment of Hpv-related Benign, Premalignant, and Malignant Diseases
27 Jul 23
Methods of treating human papillomavirus (HPV)-induced conditions, HPV-induced lesions, or HPV-infected cells.
Richard Schlegel, Hang Yuan
Filed: 23 Apr 21
Utility
Nanoparticle to target cancer
11 Jul 23
Jill P. Smith, Stephan Stern, Abdullah Mahmud
Filed: 17 Dec 21
Utility
CADHERIN-11 Inhibitor Formulation and Its Uses In Immunotherapy
6 Jul 23
Provided herein are compositions and methods for the treatment and prevention of cadherin-11 (CDH11) related diseases.
Sivanesan DAKSHANAMURTHY, Ivana PERAN, Stephen W. BYERS, Shahin ASSEFNIA
Filed: 4 Jun 21
Utility
Site- and Structure-specific Core Fucosylation In Liver Disease
6 Jul 23
The instant disclosure provides methods of detecting N-glycopeptides in a sample by contacting the sample with one or more exoglycosidases and detecting the N-glycopeptides by mass spectrometry.
Radoslav GOLDMAN, Miloslav SANDA
Filed: 19 May 22
Utility
Cache optimization via topics in web search engines
4 Jul 23
Embodiments may provide a cache for query results that can adapt the cache-space utilization to the popularity of the various topics represented in the query stream.
Ophir Frieder, Ida Mele, Raffaele Perego, Nicola Tonellotto
Filed: 21 Jul 21
Utility
Use of Nad+ Precursors, Sting Inhibitors, and FXR Agonists for Inhibiting SARS-COV-2 (COVID-19)-INDUCED Cytokine Release
29 Jun 23
Methods of inhibiting release of one or more cytokines, or inhibiting a cytokine storm, or preventing cytokine release syndrome or a cytokines storm, in a subject infected with severe acquired respiratory syndrome coronavirus 2.
Moshe Levi
Filed: 22 May 21
Utility
Methods of Treating Residual Lesions of Vascular Anomalies
29 Jun 23
Compositions comprising bile acids or their salts and methods of use thereof for the treatment of residual lesions of vascular anomalies.
Cynthia Marie Carver DEKLOTZ, Michael Andrew CARDIS
Filed: 16 Dec 22