195 patents
Page 10 of 10
Utility
Harvesting Cell-Free Non-Coding RNAS (CFNCRS) From Interstitial Fluid For Sensitive Biomarkers
29 Jan 20
A system for determining the presence of cell-free non-coding RNA (cfNCR) biomarkers in interstitial fluid includes a microfluidic device for non-invasively and passively accessing interstitial fluid from a patient.
Makarand Paranjape
Filed: 30 Jan 18
Utility
Viral vectors and their use in therapeutic methods
13 Jan 20
The invention provides viral vectors (e.g., herpes viral vectors) and methods of using these vectors to treat disease.
Paul Johnson, Robert L. Martuza, Samuel D. Rabkin, Tomoki Todo
Filed: 18 Dec 16
Utility
FMRI biomarker of neurodegenerative disease
13 Jan 20
Provided herein are methods related to identifying an early, asymptomatic (prodromal) stage of a neurodegenerative disease or identifying a subject with a symptomatic neurodegenerative disease, including, for example, mild cognitive impairment (MCI), Alzheimer's Disease (AD), or HIV-associated neurocognitive disorder (HAND), using functional MRI data from the subject.
Xiong Jiang, Maximilian Riesenhuber
Filed: 13 Mar 14
Utility
Metabolic Biomarkers for Cognitive Ability
8 Jan 20
The present invention relates to methods of determining if a subject has a decreased risk of suffering from future memory impairment.
Mark E. Mapstone, Howard J. Federoff, Massimo S. Fiandaca, Amrita K. Cheema
Filed: 1 Feb 18
Utility
Compositions and Methods for Treating Lysosomal Storage Disorders
1 Jan 20
Provided herein are methods of treating a lysosomal storage disorder (LSD) in a subject and methods of promoting lysosomal clearance in one or more cells of a subject.
Charbel Moussa
Filed: 8 Feb 18
Utility
System, method, and storage medium for generating hypotheses in data sets
30 Dec 19
A method for generating hypotheses in a corpus of data comprises selecting a form of ontology; coding the corpus of data based on the form of the ontology; generating ontology space based on coding results and the ontology; transforming the ontology space into a hypothesis space by grouping hypotheses; weighing hypotheses included in the hypothesis space; and applying a science-based sorting algorithm configured to model a science-based treatment of the weighted hypotheses.
Ophir Frieder, David Hartley
Filed: 14 Jan 15
Utility
System and method for detecting, collecting, analyzing, and communicating event-related information
9 Dec 19
A system and method involves detecting operational social disruptive events on a global scale, assigning disease or non-disease event staging and warnings to express data in more simplistic terms, modeling data in conjunction with linguistics analysis to establish responsive actions, generating visualization and modeling capabilities for communicating information, and modeling disease or non-disease propagation for containment and forecasting purposes.
Ahmed A. Humayun, Steven J. Silverstein, Gregory P. Zalasky, Kevin D. Jones
Filed: 26 Jul 17
Utility
Cache optimization via topics in web search engines
9 Dec 19
Embodiments may provide a cache for query results that can adapt the cache-space utilization to the popularity of the various topics represented in the query stream.
Ophir Frieder, Ida Mele, Raffaele Perego, Nicola Tonellotto
Filed: 9 May 19
Utility
Targeting Tumor Cells with Chemotherapeutic Agents Conjugated to Matriptase Antibodies
27 Nov 19
The present invention relates to matriptase antibodies and immunoconjugates of matriptase antibodies with cytotoxic agents and the use thereof for killing or inhibiting the growth of matriptase-expressing cancer cells, such as those of multiple myeloma and breast cancers.
Siang-Yo Lin, Joseph R. Bertino, Chen-Yong Lin
Filed: 7 Aug 19
Utility
Small molecule androgen receptor inhibitors and methods of use thereof
25 Nov 19
Small molecule carbazole compounds for use as androgen receptor inhibitors are provided herein.
Milton L. Brown, Shujie Hou, Partha Banerjee, Karishma Amin
Filed: 6 Nov 18
Utility
System and method for deterring malicious network attacks
18 Nov 19
A system and method for deterring malicious network attacks.
Thomas Clay Shields
Filed: 28 Nov 18
Utility
Boronic acid derivatives of resveratrol for activating deacetylase enzymes
18 Nov 19
Disclosed herein are compounds, compositions and methods for the treatment of a disease or disorder related to activation of deacetylase enzymes.
Insoo Bae, Yong Weon Yi, Hyo Jin Kang, Hee Jeong Kim
Filed: 2 Jul 14
Utility
Flavivirus protease inhibitors
11 Nov 19
Methods of treating or preventing a Flavivirus infection in a subject are provided.
Radhakrishnan Padmanabhan, Tadahisa Teramoto, Mark Manzano
Filed: 22 Oct 13
Utility
Dryer for preparation of dry nanoparticles
11 Nov 19
A system for producing dry nanoparticles from a liquid includes a closed tubing system which incorporates a mister, heater and an electrostatic collector therein.
Edward Van Keuren, Grace Maglieri, Roman Kosarzycki, Leon Der
Filed: 26 Sep 17
Utility
Fluorescent regulators of RASSF1A expression and human cancer cell proliferation
28 Oct 19
The invention provides methods for the treatment of cancer in a subject comprising administering a dansyl-carbazole compound.
Milton L. Brown, Kathryn D. Sheikh, Mikell A. Paige, Partha Banerjee, Shankar Jagadeesh
Filed: 13 Aug 09