195 patents
Page 8 of 10
Utility
Cache Optimization Via Topics In Web Search Engines
11 Nov 20
Embodiments may provide a cache for query results that can adapt the cache-space utilization to the popularity of the various topics represented in the query stream.
Ophir Frieder, Ida Mele, Raffaele Perego, Nicola Tonellotto
Filed: 15 Oct 19
Utility
Enhancing the legibility of images using monochromatic light sources
9 Nov 20
A system and method are described for enhancing readability of document images by operating on each document individually.
Ophir Frieder, Gideon Frieder, Jon Parker
Filed: 29 Oct 18
Utility
Viral Vectors and Their Use In Therapeutic Methods
4 Nov 20
The invention provides viral vectors (e.g., herpes viral vectors) and methods of using these vectors to treat disease.
Paul Johnson, Robert L. Martuza, Samuel D. Rabkin, Tomoki Todo
Filed: 9 Jan 20
Utility
Small molecule inhibitors of XBP1 splicing
19 Oct 20
Small molecule inhibitors of XBP1 splicing by IRE1α are provided, as well as methods for their use in treating or preventing cancer (e.g., endocrine resistant breast cancer), diabetes, and obesity.
Sivanesan Dakshanamurthy, Milton L. Brown, Robert Clarke, Ayesha N. Shajahan-Haq, Jacqueline Smith
Filed: 15 May 16
Utility
Methods and Compositions Overcoming Cancer Cell Immune Resistance
7 Oct 20
Methods and compositions are provided for preventing the loss of cell surface adhesion molecules and thus prevent or delay acquisition of a ADCC resistance phenotype mediated by lower expression of several cell surface molecules that contribute to cell:cell interactions and immune synapse formation including tumor target antigens, MHC Class I/II molecules and cell adhesion proteins.
Louis M. Weiner
Filed: 29 Mar 20
Utility
Epitaxial Graphene Quantum Dots for High-Performance Terahertz Bolometers
30 Sep 20
Devices including graphene quantum dots yield extremely high performance THz bolometers, by measuring the current of hot electrons formed in the graphene source and drain electrodes of the device and propagating through the graphene quantum dot connected thereto.
Abdel El Fatimy, Paola Barbara, Kurt Gaskill
Filed: 5 Dec 16
Utility
Radiation Mitigator and Method of Use Thereof
30 Sep 20
Milton L. Brown, Yali Kong, Courtney Houchen, Sripathi M. Sureban, Parthasarathy Chandrakesan
Filed: 30 Mar 17
Utility
Determining stereoisomeric excess, concentration and absolute configuration
28 Sep 20
The present invention is directed to analytical methods for determining the concentration, and/or stereoisomeric excess, and/or absolute configuration of chiral analytes in a sample.
Christian Wolf, Peng Zhang
Filed: 7 Jun 18
Utility
Enhancing the Legibility of Images Using Monochromatic Light Sources
16 Sep 20
A system and method are described for enhancing readability of document images by operating on each document individually.
Ophir Frieder, Gideon Frieder, Jon Parker
Filed: 25 May 20
Utility
Automatic Re-analysis of Genetic Testing Data
16 Sep 20
Disclosed herein are systems and methods for the automatic re-analysis of genetic testing data.
Abhishek Pandey, Howard Federoff, Ophir Frieder
Filed: 6 Apr 20
Utility
Treatments and Methods for Controlling Hypertension
16 Sep 20
The present invention relates to methods of treating hypertension in a subject in need of treatment thereof, with the methods comprising administering a pharmaceutically effective amount of an angiotensin II inhibitor and a pharmaceutically effective amount of a receptor tyrosine kinase inhibitor to the subject.
Anton Wellstein
Filed: 18 Nov 18
Utility
Process for Continuous Cell Culture of GPSCS
9 Sep 20
The present invention is directed towards methods of culturing germline pluripotent stem cells (gPSCs), with the methods comprising culturing the cells in a cell culture medium while inhibiting the activity of Rho kinase (ROCK) in the cells during culture.
Ian Gallicano, Samiksha Mahapatra, Dianna Martin
Filed: 19 Nov 18
Utility
(R)-12-HYDROXYSTEARIC Acid Hydrazides As Gelators and Self-standing Gels Thereof
26 Aug 20
(R)-12-hydroxystearic acid hydrazides as gelators and gels generated therefrom are provided.
Jingjing LI, Richard G. Weiss
Filed: 27 Dec 16
Utility
Predicting the Popularity of a Song Based on Harmonic Surprise
19 Aug 20
A system and method for estimating the popularity of song by calculating the (absolute and/or contrastive) harmonic surprise of each song in a corpus of music data, determining the popularity of each song in the corpus (e.g., based on a music chart, downloads, online streams), determining correlations between harmonic surprise and popularity, and estimating the popularity of an individual song based on the (absolute and/or contrastive) harmonic surprise of the individual song and the correlations between harmonic surprise and popularity.
Scott Miles
Filed: 9 Feb 20
Utility
Application programming interface and hypergraph transfer protocol supporting a global hypergraph approach to reducing complexity for accelerated multi-disciplinary scientific discovery
10 Aug 20
A system and method for connecting one or more client applications with one or more knowledge representation servers and communicating there between includes an application programming interface (API) and a hypergraph transfer protocol (HGTP), for facilitating communication between the one or more client applications and one or more knowledge representation servers responsive to a client application request.
J. Cory Smart
Filed: 4 Jun 17
Utility
Small Molecule Inhibitors of SLC25A1
5 Aug 20
Methods of treating or preventing cancer, diabetes, and/or obesity in a subject are provided.
Maria Laura Avantaggiati, Mikell Paige
Filed: 2 Aug 18
Utility
Treatments of Metabolic Disorders Using FGF Binding Protein 3
5 Aug 20
The invention relates to methods of treating a metabolic disorder in a subject, the method comprising administering fibroblast growth factor binding protein 3 (FGFBP3) or a variant thereof to a subject in need of treatment of a metabolic disorder.
Anton Wellstein
Filed: 2 Apr 20
Utility
Small Molecule Androgen Receptor Inhibitors and Methods of Use Thereof
5 Aug 20
Small molecule carbazole compounds for use as androgen receptor inhibitors are provided herein.
Milton L. Brown, Shujie Hou, Partha Banerjee, Karishma Amin
Filed: 22 Oct 19
Utility
Plasma MicroRNA Markers of Upper Limb Recovery Following Human Stroke
29 Jul 20
Methods of determining if a subject has an increased risk of poor recovery after suffering a stroke and methods of treating a subject recovering from a stroke.
Matthew A. Edwardson, Xiaogang Zhong, Massimo S. Fiandaca, Howard J. Federoff, Amrita K. Cheema, Alexander W. Dromerick
Filed: 23 Jan 20
Utility
Genetic markers for memory loss
20 Jul 20
The present invention relates to methods of determining if a subject has an increased risk of suffering from memory impairment.
Massimo S. Fiandaca, Mark E. Mapstone, Yuriy Gusev, Howard J. Federoff
Filed: 27 May 15