1919 patents
Page 3 of 96
Utility
Methods and Compositions for Differentiating Stem Cells
14 Dec 23
The subject matter disclosed herein is generally directed to modulation of genes and pathways that drive differentiation of LGR5+ stem cells.
Benjamin Mead, Alexander K. Shalek, Jeffrey Karp, Kazuki Hattori
Filed: 25 Oct 21
Utility
Delivery, Engineering and Optimization of Systems, Methods and Compositions for Sequence Manipulation and Therapeutic Applications
14 Dec 23
The invention provides for delivery, engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of target sequences.
Feng ZHANG
Filed: 30 Jun 23
Utility
Methods and Compositions for Treating or Preventing a Vaginal Infection of Gardnerella Vaginalis
14 Dec 23
Methods of treating or preventing a vaginal infection of Gardnerella vaginalis in a subject involve administering to the subject an effective amount of a composition.
Katharina Ribbeck, Laura L. Kiessling, Caroline Andrea Werlang, Spencer D. Brucks, Liubov Yakovlieva, Kelsey Morgan Wheeler
Filed: 13 Jun 23
Utility
Sintered Nanocrystallinealloys
14 Dec 23
Provided in one embodiment is a method, comprising: sintering a plurality of nanocrystalline particulates to form a nanocrystalline alloy, wherein at least some of the nanocrystalline particulates may include a non-equilibrium phase comprising a first metal material and a second metal material, and the first metal material may be soluble in the second metal material.
Christopher A. Schuh, Mansoo Park
Filed: 27 Mar 23
Utility
Ultrafast Detector of Rydberg Atoms
14 Dec 23
A device, comprising at least one monochromatic light source configured to generate a first optical trap; an ensemble of particles disposed in the first optical trap, each particle of the ensemble of particles being excitable to a first Rydberg state and a second Rydberg state, the second Rydberg state having a blockade radius, each particle of the ensemble of particles being within the blockade radius of each other and within the blockade radius of an atomic qubit, the atomic qubit being a particle that is excitable to the second Rydberg state, the ensemble of particles having a first transmissivity at a first wavelength when neither any particle of the ensemble of particles nor the atomic qubit is in the second Rydberg state, the ensemble of particles having a second transmissivity at the first wavelength when the atomic qubit is in the second Rydberg state, the second transmissivity being lower than the first transmissivity; and a second monochromatic light source configured to drive each particle of the ensemble of particles into the first Rydberg state; a probe light source configured to direct a probe beam having the first wavelength to the ensemble of particles; and a photosensor configured to determine the state of the atomic qubit.
Wenchao Xu, Vladan Vuletic, Sergio Hiram Cantu, Valentin Klueseger, Aditya Vignesh Venkatramani, Mikhail D. Lukin, Tamara Sumarac
Filed: 11 Aug 23
Utility
Heteroepitaxially Integrated Compound Semiconductor Optical Devices with On-Chip Waveguides
14 Dec 23
A III-V/SiNx hybrid integrated photonics platform is described.
Christopher Heidelberger, Cheryl Marie SORACE-AGASKAR, Jason PLANT, Boris KHARAS, Reuel B. SWINT, Yifei Li, Paul William JUODAWLKIS
Filed: 15 May 23
Utility
Reticle Exchange Device with Reticle Levitation
7 Dec 23
An electrostatic chuck includes electrodes to clamp a workpiece, electrodes to electrostatically levitate and position the workpiece, and sensors to detect position and orientation of the workpiece.
David L. Trumper, Brij Mohan Bhushan
Filed: 12 Nov 21
Utility
Magnetomicrometric Advances in Robotic Control
7 Dec 23
Systems and methods relating to magnetomicrometry and magnetic-target-based mechanomyography are provided.
Hugh M. Herr, Cameron Roy Taylor, Seong Ho Yeon, Michael Thomas Nawrot
Filed: 21 Oct 21
Utility
Multilayered Microhydraulic Actuators
7 Dec 23
An actuator with a stack of thin layers operates by electrowetting droplets between the layers.
Jakub T. KEDZIERSKI
Filed: 17 Aug 23
Utility
Reprogrammable Iscb Nucleases and Uses Thereof
7 Dec 23
Systems, methods and compositions for targeting polynucleotides are detailed herein.
Feng Zhang, Han Altae-Tran, Soumya Kannan, Fatma Esra Demircioglu
Filed: 22 Oct 21
Utility
Integrated Freeform Optical Couplers And Fabrication Methods Thereof
7 Dec 23
The present technology is related to optics and optical systems, particularly to photonic packaging, optical coupling, optical interconnects, micro-optics, and their fabrication.
Luigi Ranno, Tian GU, Juejun Hu
Filed: 5 Jun 23
Utility
Gastric Resident Electronics
30 Nov 23
Gastric resident electronics, devices, systems, and related methods are generally provided.
Robert S. Langer, Carlo Giovanni Traverso, Yong Lin Kong
Filed: 12 May 23
Utility
Nucleic Acid-guided Nucleases and Use Thereof
30 Nov 23
Systems, methods, and compositions for targeting polynucleotides.
Feng Zhang, Soumya Kannan, Han Altae-Tran
Filed: 22 Oct 21
Utility
Molybdenum-containing Alloys and Associated Systems and Methods
30 Nov 23
Molybdenum-containing alloys, and associated systems and methods, are generally described.
Christopher A. Schuh, Christian Oliver
Filed: 3 Aug 23
Utility
Site Specific Genetic Engineering Utilizing Trans-template Rnas
30 Nov 23
Provided herein are compositions comprising, inter alia, a ttRNAs comprising (i) a primer binding site, (ii) a reverse transcriptase template sequence, (iii) an aptamer, and (iv) an integration sequence comprising an integration site.
Omar Abudayyeh, Jonathan Gootenberg, Kaiyi Jiang
Filed: 19 Apr 23
Utility
Multi-phase Electrochemical Cells and Related Systems and Methods
30 Nov 23
Multi-phase electrochemical cells and related systems and methods are generally described.
Yet-Ming Chiang, Andres Badel, Fei Wang
Filed: 10 Apr 23
Utility
Type VI Crispr Orthologs and Systems
30 Nov 23
The invention provides for systems, methods, and compositions for targeting nucleic acids.
Feng Zhang, Omar O. Abudayyeh, Jonathan Gootenberg, Eric S. Lander
Filed: 13 Jun 23
Utility
Spin Torque Oscillator Maser
30 Nov 23
An oscillator comprising, a cavity wherein the cavity comprises an electrical conductor.
Luqiao LIU, Justin HOU, Pengxiang ZHANG
Filed: 31 Mar 23
Utility
Systems, Methods, and Compositions for Rna-guided Rna-targeting Crispr Effectors
30 Nov 23
This disclosure provides systems, methods, and compositions for RNA-guided RNA-targeting CRISPR effectors for the treatment of diseases, and for use as diagnostics.
Omar Osama Abudayyeh, Jonathan S. Gootenberg, Wenyuan Zhou, Hiroshi Nishimasu, Kazuki Kato, Cian Franz Schmitt-Ulms
Filed: 24 May 23
Utility
Type I Crispr-associated Transposase Systems
30 Nov 23
Systems and methods for targeted gene modification, targeted insertion, perturbation of gene transcripts, and nucleic acid editing.
Feng Zhang, Makoto Saito, Jonathan Strecker
Filed: 8 Oct 21