83 patents
Page 3 of 5
Utility
Perineural Administration of Resiniferatoxin for Treatment of Maladaptive Pain
23 Dec 21
Disclosed herein are methods of administering resiniferatoxin (RTX) perineurally for treatment of maladaptive pain, and compositions for use in such methods.
Alexis Nahama
Filed: 11 Jun 21
Utility
MEDICAL DEVICES FOR DELIVERY OF siRNA
23 Dec 21
Disclosed are medical devices that incorporate siRNA.
Russell Frederick Ross
Filed: 1 Sep 21
Utility
Variant Antibodies That Bind OX40
23 Dec 21
The present disclosure provides variant anti-OX40 antibodies that mimic the activity of OX4OL by behaving as an agonist against receptor OX40 to enhance T cell clonal expansion and differentiation.
Min Soo Kim
Filed: 23 Aug 21
Utility
Antigen Binding Proteins that Bind BCMA
16 Dec 21
The present disclosure provides BCMA binding proteins, particularly anti-BCMA antibodies, or antigen-binding portions thereof, that specifically bind BCMA and uses thereof.
Heyue Zhou, Xia Cao
Filed: 25 Aug 21
Utility
Antigen Binding Proteins That Bind PD-L1
28 Oct 21
There is disclosed compositions and methods relating to or derived from anti-PD-L1 antibodies.
Heyue Zhou, Randy Gastwirt, Barbara A. Swanson, John Dixon Gray, Gunnar F. Kaufmann
Filed: 3 May 21
Utility
Methods for Treating Parkinson?s Disease by Administering Resiniferatoxin
30 Sep 21
There is disclosed a method for treating Parkinson's Disease (PD) comprising administering an effective amount of Resiniferatoxin (RTX) by an intrathecal or intracisternal administration.
Alexis Nahama, Henry Hongjun Ji
Filed: 11 Jun 21
Utility
Antibody Drug Conjugates Having Derivatives of Amatoxin As The Drug
26 Aug 21
There is disclosed derivatives of amanitin conjugated to a targeting antibody to form an ADC (antibody drug conjugate).
Tong Zhu, Hong Zhang, Alisher B. Khasanov, Gang Chen
Filed: 26 Apr 21
Utility
Drug Delivery Methods Targeting the Lymphatic System
29 Jul 21
Disclosed herein is a method for administering a therapeutic agent to multiple regions of the lymphatic system of a patient.
RUSSELL FREDERICK ROSS
Filed: 30 May 19
Utility
Compositions and Methods Comprising an Anti-CD47 Antibody in Combination with a Tumor Targeting Antibody
22 Jul 21
The present disclosure provides compositions and methods comprising a first antibody comprising a fully human anti-CD47 antibody and a second antibody comprising an Fc portion that binds an Fcγ receptor on an effector cell.
Damien Bresson, Heyue Zhou, Christophe Pedros
Filed: 4 Dec 20
Utility
Cartridge Portion of Transdermal Drug Delivery Apparatus and Methods
1 Jul 21
A cartridge, which may be suitable for use as a portion of a transdermal drug delivery apparatus, may include a body at least partially defining an interior for containing fluid for being delivered by the transdermal drug delivery apparatus.
Andrew T. Baker, Russell F. Ross, Elizabeth Deibler Gadsby, Luke Hagan
Filed: 3 Feb 21
Utility
Drug-Conjugates, Conjugation Methods, And Uses Thereof
24 Jun 21
In one aspect, an active agent-conjugate, methods of preparing the active agent-conjugate, and uses thereof is provided.
Zhenwei Miao, Yufeng Hong, Tong Zhu, Alexander Wilhelm Chucholowski
Filed: 1 Mar 21
Utility
Transdermal Drug Delivery Device
10 Jun 21
A transdermal drug delivery device is disclosed that may comprise a housing including an upper housing portion and a lower housing portion.
Russell F. Ross, Luke Hagan, Alexander Malkin, Derek Hatchett, Jacob Marks, Thomas Lutzow
Filed: 18 Feb 21
Utility
Antibody Therapeutics That Bind CD123
3 Jun 21
There is disclosed compositions and methods relating to or derived from anti-CD123 antibodies.
HEYUE ZHOU, JOHN DIXON GRAY
Filed: 15 Jan 21
Utility
Antigen Binding Proteins that Bind PD-L1
20 May 21
There is disclosed anti-PD-L1 IgG class antibodies that have an improved ability to be manufactured at higher yields.
Heyue Zhou
Filed: 13 Jan 21
Utility
Cell Internalizing Compounds
13 May 21
Yanwen Fu, Gunnar F. Kaufmann, Heehyoung Lee, Tong Zhu, Henry Hongjun Ji
Filed: 20 Jan 21
Utility
Variant Antibody That Binds Cd38
6 May 21
The present disclosure provides anti-CD38 IgG class antibody having improved ability to be manufactured at higher yields compared to the parent antibody having the original wild type sequence.
Barbara A. Swanson, Heyue Zhou, Jian Cao
Filed: 18 Dec 20
Utility
Antigen Binding Proteins that Bind PD-1
6 May 21
There is disclosed compositions and methods relating to or derived from anti-PD-1 antibodies.
Heyue Zhou, Barbara A. Swanson, John Dixon Gray, Gunnar F. Kaufmann, Edwige Gros
Filed: 14 Jan 20
Utility
Disulfide Bridging Conjugates
25 Feb 21
James T. Patterson, Gunnar F. Kaufmann, Yanwen Fu, Tong Zhu
Filed: 31 Aug 20
Utility
Methods for Better Delivery of Active Agents to Tumors
25 Feb 21
The present invention concerns delivery of agents through the skin.
Russell F. Ross
Filed: 16 Sep 20
Utility
Composite Microneedle Array Including Nanostructures Thereon
18 Feb 21
Disclosed are composite microneedles arrays including microneedles and a film overlaying the microneedles.
Russell Frederick Ross
Filed: 23 Sep 20