196 patents
Page 8 of 10
Utility
Methods for scaling between chromatographic systems using highly compressible fluids
1 Jun 21
Methods for transferring a separation procedure from a first chromatographic system to a second one are disclosed that involve substantially matching a pressure profile.
Jason F. Hill, Michael O. Fogwill, Joseph D. Michienzi, Joshua A. Shreve, Abhijit Tarafder
Filed: 9 Apr 18
Utility
Techniques for processing of mass spectral data
18 May 21
Techniques for performing data acquisition and analysis are described.
Scott J. Geromanos, Steven J. Ciavarini, Curt Devlin
Filed: 17 Jan 20
Utility
Sample organizer, tray, system and method
11 May 21
A liquid chromatography sample organizer includes a first chamber, a plurality of stacked sample organizer shelves mounted within the first chamber each individually configured to store a sample-vial carrier including a sample, and a shelf magnet affixed to a surface of each of the plurality of stacked sample organizer shelves.
David A. Simpson, Joshua A. Burnett, Marc E. Lemelin, Paul Keenan, Peter Osswald
Filed: 12 Jun 19
Utility
Method and apparatus for scaling between chromatographic systems using highly compressible fluids
4 May 21
Methods for transferring a carbon dioxide based separation procedure from a reference chromatographic system to a target chromatographic system involve alternative techniques for determining system pressure drops not attributable to the column.
Joseph D. Michienzi, Joshua A. Shreve, Jason F. Hill, Abhijit Tarafder, Michael O. Fogwill, Keith Fadgen
Filed: 9 Apr 18
Utility
High purity chromatographic materials comprising an ionizable modifier
13 Apr 21
The present invention provides novel chromatographic materials, e.g., for chromatographic separations, processes for its preparation and separations devices containing the chromatographic material; separations devices, chromatographic columns and kits comprising the same; and methods for the preparation thereof.
Kevin D. Wyndham, Pamela C. Iraneta, Thomas H. Walter
Filed: 28 Nov 18
Utility
Multi-injection mode valve module
23 Mar 21
A chromatography system has an associated system volume and a sample dispersion volume.
Sylvain Cormier, Richard W. Andrews, Peyton C. Beals
Filed: 17 Feb 16
Utility
System and method for diagnosing a condition of a restrictor
23 Mar 21
The present disclosure relates to methodologies, systems, apparatus, and kits for diagnosing the condition of a restrictor element in a chromatography system based on flow rate measurements, or pressure measurements, or both.
Michael O. Fogwill
Filed: 11 Oct 18
Utility
Systems, methods, and devices providing solvent container identification and incorporation
23 Mar 21
Solvent containers and solvent container trays for chromatography systems are described for providing control over solvent supply and waste collection.
Xiangjin Song, James P. Murphy, Keith Fadgen, Wade P. Leveille, Joseph D. Michienzi, Jonathan L. Belanger, Moon Chul Jung, Abhijit Tarafder
Filed: 17 Jan 18
Utility
System and method for minimization of force variation in a solenoid within a pressurized flow system
28 Dec 20
Exemplary embodiments are directed to systems and methods used to minimize force variation from a solenoid through an operating stroke.
Joshua A. Shreve
Filed: 6 Mar 13
Utility
Flame ionization detection burner assemblies for use in compressible fluid-based chromatography systems
28 Dec 20
Burner assemblies of flame-based detectors are configured to deliver decompressed mobile phase of supercritical fluid chromatography systems to the flame of a flame-based detector while providing for improved optimization of analyte response as well as enhanced flame stability during operation.
Michael O. Fogwill, Joseph D. Michienzi, James P. Murphy
Filed: 7 Jan 19
Utility
Managing fluidic connections to microfluidic devices
14 Dec 20
A method may include reducing fluid flow between a rotor and a microfluidic device.
Geoff C. Gerhardt, Keith Fadgen, Joseph D. Michienzi, Bernard Bunner
Filed: 10 Apr 19
Utility
Chromatographic compositions
7 Dec 20
Provided herein are stationary phase compositions comprising a chromatographic surface of porous or non-porous core material comprising a surface modifier for use in chromatographic separations.
Matthew A. Lauber, Daniel P. Walsh
Filed: 14 Mar 18
Utility
Textured needle for improved piercing performance in liquid chromatography applications
7 Dec 20
A needle for aspirating a sample from a sample source and injecting the sample into a liquid chromatography system, the needle including a needle body having a rough textured surface finish for at least a portion of the needle body, wherein the rough textured surface finish reduces a coefficient of friction of the needle body, is provided.
Scott Kelley, Peter Osswald, Rose Solow, John M. Auclair
Filed: 4 Mar 19
Utility
Method and apparatus for flame ionization detection for chromatography
30 Nov 20
A method for detecting an analyte in a chromatography system includes performing a separation using a mobile phase that includes an organic component.
Michael O. Fogwill, Joseph D. Michienzi, Geoff Gerhardt
Filed: 18 Apr 17
Utility
Rapid authentication using surface desorption ionization and mass spectrometry
23 Nov 20
The present disclosure relates generally to rapid authentication methods using surface desorption ionization and mass spectrometry detection.
Gareth E. Cleland, Kari L. Organtini
Filed: 13 Apr 17
Utility
Catalytic oxidation of polar modifiers in chromatographic mobile phases
9 Nov 20
The present disclosure relates to an oxidizer, and related methods, for oxidizing polar modifiers in chromatographic mobile phases.
Michael O. Fogwill, Joseph D. Michienzi, James P. Murphy
Filed: 20 Nov 18
Utility
Gas liquid separator and associated methods
2 Nov 20
Exemplary embodiments are directed to a gas liquid separator that includes a chamber for receiving a fluid mixture, a fluid mixture inlet, a solvent outlet, and a gas outlet.
Joshua A. Shreve
Filed: 23 Oct 17
Utility
Techniques for mass analyzing a complex sample based on nominal mass and mass defect information
2 Nov 20
Techniques and apparatus for analyzing mass spectrometry data are described.
Scott J. Geromanos, Curt Devlin, Steven J. Ciavarini
Filed: 20 Nov 17
Utility
Modifier stream elution of trap column for multidimensional compressible fluid-based chromatography
2 Nov 20
A method of performing a chromatographic separation includes modulating a portion of a flowstream to a trap column to retain at least one analyte from the flowstream on the trap column.
Michael O. Fogwill, Isabelle François
Filed: 20 Dec 17
Utility
Systems, methods, and devices for providing pressurized solvent flow
2 Nov 20
The present disclosure generally relates to systems, methods and devices for providing pressurized solvent flow in chromatography systems.
Wade P. Leveille, Jonathan L. Belanger, Moon Chul Jung, Abhijit Tarafder, Joseph Michienzi, Keith Fadgen, Kevin Wyndham, Xiangjin Song
Filed: 18 Dec 17