1919 patents
Page 13 of 96
Utility
Biomass Conversion Reactors and Associated Systems and Methods
11 May 23
Systems and methods associated with biomass decomposition are generally described.
Kevin S. Kung, Alexanader H. Slocum, Santosh Janardhan Shanbhogue, Ahmed Fouad Ghoniem, Robert James Stoner
Filed: 28 Apr 22
Utility
Fluidic Platforms for Perfusable Vascularized Tissues with Infiltrates
11 May 23
Microfluidic devices with open ports and gel channels for forming perfusable hydrogel vascular networks with holes or ports for samples, and methods of making and using, are provided which integrate interstitial flows to an ex vivo vascularized tissue model.
Roger Kamm, Huu Tuan Nguyen, Sharon Wei Ling Lee
Filed: 23 Feb 22
Utility
Silicon Nano Light Emitting Diodes
4 May 23
Light-emitting diodes having radiative recombination regions with deep sub-micron dimensions are described.
Rajeev J. RAM, Jaehwan Kim, Jin Xue, Zheng Li
Filed: 10 Dec 21
Utility
Privilege Metric for Evaluating the Security of a Library
4 May 23
A privilege metric application quantifies a privilege reduction for a subject software module MS.
Nikolaos Vasilakis
Filed: 31 Oct 22
Utility
Compositions, Articles, Devices, and Methods Related to Droplets Comprising a Cloaking Fluid
4 May 23
Described herein are compositions and articles related to droplets comprising a carrier fluid and a cloaking fluid, and associated methods of and devices for depositing the droplets on surfaces.
Kripa K. Varanasi, Vishnu Jayaprakash, Sreedath Panat, Simon B. Rufer
Filed: 27 Oct 22
Utility
Systems, Methods, and Compositions for Site-specific Genetic Engineering Using Programmable Addition Via Site-specific Targeting Elements (Paste)
4 May 23
This disclosure provides systems, methods, and compositions for site-specific genetic engineering using Programmable Addition via Site-Specific Targeting Elements (PASTE).
Omar Abudayyeh, Jonathan Gootenberg
Filed: 14 Dec 22
Utility
Anti-fouling Coatings and Associated Systems and Methods
4 May 23
Anti-fouling coatings and associated systems and methods are generally described.
Michael Short, Bilge Yildiz, Max Carlson, Cigdem Toparli, Minh Dinh
Filed: 9 Mar 21
Utility
Materials and Methods for Biosorption of Micropollutants from Aqueous Solutions
4 May 23
A method for removing organic or inorganic micropollutants from aqueous solutions includes adding a biomass of biomaterial to the solutions, the biomaterial being an active or inactive biological organism, such as a yeast, having affinity for biosorption (adsorption by the biomass)of an organic or inorganic micropollutant present in the solution at, or below, a parts-per-billion concentration, and controlling the pH and temperature of the solution, as well as contact time and agitation, to be within a range suitable for biosorption of the at micropollutant by the biomaterial.
Patritsia Maria Stathatou, Filippos Tourlomousis, Christos Edouardos Athanasiou, Andreas Mershin, Neil A. Gershenfeld
Filed: 8 Sep 22
Utility
Devices and Systems for Delivery of Materials to Cells
27 Apr 23
A microfluidic system for causing perturbations in a cell membrane, the system including a microfluidic channel defining a lumen and being configured such that a cell suspended in a buffer can pass therethrough, wherein the microfluidic channel includes a cell-deforming constriction, wherein a diameter of the constriction is a function of the diameter of the cell.
Armon R. Sharei, Andrea Adamo, Robert S. Langer, Klavs F. Jensen
Filed: 25 Oct 21
Utility
Superelastic and Shape-Memory Fe-Based Wire and Direct Wire Casting Thereof
27 Apr 23
Herein is provided a ferrous shape memory alloy (SMA) wire and processes for production of ferrous shape memory alloy wire that do not require crystallographic texturing processes to achieve superior superelastic and SMA wire properties.
EDWARD PANG, CHRISTOPHER A. SCHUH, WONSEOK CHOI
Filed: 2 Apr 21
Utility
Field Deployable Crispr-cas Diagnostics and Methods of Use Thereof
27 Apr 23
Systems and methods for rapid diagnostics related to the use of CRISPR effector systems and optimized guide sequences for detection of coronavirus, including multiplex lateral flow diagnostic devices and methods of use, are provided.
Jonathan Gootenberg, Omar Abudayyeh, Julia Joung, Alim Ladha, Han Altae-Tran, Guilhem Faure, Feng Zhang
Filed: 12 Feb 21
Utility
Systems and Methods for Guided Intervention
27 Apr 23
Systems and methods are provided for semi-automated, portable, ultrasound guided cannulation.
Laura J. Brattain, Anthony E. Samir, Brian A. Telfer, Matthew Johnson, Nancy DeLosa, Lars Gjesteby, Theodore T. Pierce, Joshua Werblin
Filed: 21 Oct 22
Utility
Modified Alginates for Cell Encapsulation and Cell Therapy
27 Apr 23
Covalently modified alginate polymers, possessing enhanced biocompatibility and tailored physiochemical properties, as well as methods of making and use thereof, are disclosed herein.
Arturo J. Vegas, Minglin Ma, Kaitlin M. Bratlie, Daniel G. Anderson, Robert S. Langer
Filed: 20 May 22
Utility
Metal-Organic Chalcogenolates
27 Apr 23
A metal-organic chalcogenolate (MOC) includes silver phenylselenolate functionalized with at least one functional group.
William A. Tisdale, Watcharaphol Paritmongkol, Tomoaki Sakurada
Filed: 25 Oct 21
Utility
Composite Anti-fouling Coatings and Associated Systems and Methods
20 Apr 23
Composite anti-fouling coatings and associated systems and methods are generally described.
Michael Short, Max Carlson, Robert Simpson
Filed: 9 Mar 21
Utility
Single-cell Rna Sequencing Using Click-chemistry
20 Apr 23
The present disclosure relates to a method of sequencing nascent RNA in a cell.
Phillip A. Sharp, Dig Mahat
Filed: 2 Nov 22
Utility
Adaptive Causal Network Coding with Feedback
20 Apr 23
Techniques are disclosed for an adaptive and causal random linear network coding (AC-RLNC) with forward error correction (FEC) for a communication channel with delayed feedback.
Muriel Medard, Derya Malak, Alejandro Cohen
Filed: 12 Dec 22
Utility
Base Editor Predictive Algorithm and Method of Use
20 Apr 23
The present disclosure provides a novel machine learning model capable of assisting those of ordinary skill in the art to conduct base editing by, inter alia, facilitating the selection of an appropriate guide RNA and base editor combination which are capable of conducting base editing at a certain level of efficiency and specificity on a given input target DNA sequence desired to be edited to produce an outcome genotype of interest.
David R. Liu, Mandana Arbab, Max Walt Shen, Christopher Cassa
Filed: 5 Feb 21
Utility
Microrna-based Logic Gates and Uses Thereof
20 Apr 23
The present disclosure, at least in part, relates to a miRNA based logic gate that comprises an engineered RNA carrier that comprises an nuclear export signal, a target site for a first miRNA and a pre-miRNA sequence for a second miRNA.
Ron Weiss, Giulio Alighieri
Filed: 1 Nov 22
Utility
Deaminase-based Rna Sensors
20 Apr 23
RNA editing tools for use in systems designed to measure RNA in vivo and manipulate specific cell types are disclosed herein.
Kaiyi Jiang, Rohan Neil Krajeski, Omar Osama Abudayyeh, Jonathan S. Gootenberg, Yifan Zhang, Fei Chen, Xi Chen, Jeremy G. Koob
Filed: 14 Jun 22