1919 patents
Page 10 of 96
Utility
Radio-frequency Power Generator and Control Method
3 Aug 23
A power generator includes a plurality of amplifier blocks and a combiner.
Haoquan Zhang, Anas Al Bastami, David J. Perreault
Filed: 13 Apr 23
Utility
A Fully Differential Piezoelectric Microphone and Amplifier System for Cochlear Implants and Other Hearing Devices
3 Aug 23
A piezoelectric sensor and amplifier for use with an auditory aid device are disclosed.
Jeffrey H. Lang, Aaron J. Yeiser, Hideko Heidi Nakajima, Ioannis Kymissis, Elizabeth Olson, Christopher I. McHugh, Lukas Graf
Filed: 1 Feb 23
Utility
Systems and Methods for Determining Cardiac Output
27 Jul 23
The systems and methods described herein determine metrics of cardiac or vascular performance, such as cardiac output, and can use the metrics to determine appropriate levels of mechanical circulatory support to be provided to the patient.
Qing Tan, Ahmad El Katerji, Noam Josephy, Elazer R. Edelman, Brian Yale Chang, Steven Keller, Sonya Sanat Bhavsar
Filed: 23 Dec 22
Utility
Targeting BCL11A Enhancer Functional Regions for Fetal Hemoglobin Reinduction
27 Jul 23
Provided herein are nucleic acid molecules that target the BCL11A enhancer functional regions, compositions comprising the nucleic acid molecules and methods for increasing fetal hemoglobin levels in a cell by disrupting BCL11A expression at the genomic level.
Daniel E. Bauer, Stuat H. Orkin, Neville Sanjana, Ophir Shalem, Feng Zhang
Filed: 30 Dec 22
Utility
Phosphorylation-based Mirna Sensor
27 Jul 23
Provided herein are genetic circuits and cell state classifiers for detecting the microRNA profile of a cell.
Ron Weiss, Ross D. Jones, Jin Huh
Filed: 11 Jul 22
Utility
Dna Nanoarrays
27 Jul 23
A DNA nanoarray includes a milliscale chip substrate; a microscale binder spot having a uniform surface bound to the substrate; and immobilized oligonucleotide sequences, each linked to the binder.
Eyal Perry, Jan Tiepelt, Joseph Jacobson
Filed: 13 Feb 23
Utility
Chimeric Amplicon Array Sequencing
27 Jul 23
The present disclosure relates to compositions and methods for nucleic acid sequencing, and specifically, at least in certain aspects, provides methods and compositions for enhancing the efficacy, throughput and/or yield of known long-range sequencing platforms, by providing chimeric arrays of input sequences.
Nir HACOHEN, Aziz AL'KHAFAJI, Paul BLAINEY, Mehrtash BABADI, Kiran V GARIMELLA, Jonathan Theodore SMITH
Filed: 14 Jun 21
Utility
Methods of Detecting Mitochondrial Diseases
27 Jul 23
Described herein are methods of determining segregation dynamics of mitochondrial DNA herein.
Vamsi Mootha, Vijay Sankaran, Caleb Lareau, Melissa Walker, Leif Ludwig, Aviv Regev
Filed: 4 Jun 21
Utility
Carbon Nanotube Field-Effect Transistors And Related Manufacturing Techniques
20 Jul 23
Described are concepts, systems, circuits, devices, structures and methods for depositing carbon nanotubes (CNTs) uniformly over a substrate.
Max SHULAKER, Mindy BISHOP
Filed: 20 Aug 21
Utility
Intravesical Drug Delivery Devices
20 Jul 23
An implantable medical device is provided for controlled drug delivery within the bladder, or other body vesicle.
Michael J. Cima, Heejin Lee
Filed: 24 Mar 23
Utility
Split Intein-based Selection for Peptide Binders
20 Jul 23
Disclosed herein, in some embodiments, non-naturally occurring proteins (e.g., non-naturally occurring modified proteins) that may be useful in the treatment of bacterial and viral infections, including SARS-CoV-2 infection, host cells comprising the same, and methods of treating bacterial and viral infections including SARS-CoV-2 infection.
Christopher A. Voigt, Andrew King, Emerson Glassey
Filed: 11 Jun 21
Utility
Inorganic-biological Hybrid System for Biofuel Production
20 Jul 23
A system for biofuel production can include a cell, a nanoparticle on a surface of the cell, and an irradiation unit configured to expose the cell to irradiation.
Shalmalee Pandit, Angela Belcher
Filed: 9 Jun 21
Utility
Programmable Nanolithography Mask
13 Jul 23
Conventional optical lithography uses masks with static patterns that are expensive and labor intensive to produce.
Aik Jun Tan, Mantao Huang, Geoffrey S. D. Beach
Filed: 2 Apr 21
Utility
Self-righting Systems, Methods, and Related Components
13 Jul 23
Self-righting articles, such as self-righting capsules for administration to a subject, are generally provided.
Robert S. Langer, Carlo Giovanni Traverso, Alex G. Abramson, Michael Williams, Jacob Wainer
Filed: 30 Dec 22
Utility
Analysis, Screening, and Selection for Soluble Protein Function In Secreted Protein Cell Libraries
13 Jul 23
Disclosed herein are methods, compositions, systems, and kits related to functional testing of soluble polypeptides in a single-cell format.
Brandon DeKosky, Matias F. Gutierrez, Chengyu Chung, Ahmed Fahad, Nicoleen Boyle, Shuyan Jin
Filed: 11 Nov 22
Utility
Cuboctahedron Lattice Materials
6 Jul 23
A method for the design, manufacture, and assembly of modular lattice structures composed of cuboctahedron unit cells.
Benjamin Jenett, Neil Gershenfeld, Kenneth Cheung, Christine Gregg
Filed: 14 Nov 22
Utility
Ribonucleoprotein Approach to Boost the Sting Signaling for Cancer Immunotherapy
6 Jul 23
Disclosed herein is a non-covalent complex, comprising: a tetramer of a recombinant protein; and an agonist of a Stimulator of Interferon Gene (STING) protein or a pharmaceutically acceptable salt thereof, wherein the recombinant protein comprises a STING protein lacking a transmembrane domain (STINGΔTM protein).
Paula HAMMOND, Yanpu HE, Jiahe LI
Filed: 11 Jun 21
Utility
Compounds, Conjugates, and Compositions of Epipolythiodiketopiperazines and Polythiodiketopiperazines and Uses Thereof
6 Jul 23
The present disclosure provides, e.g., compounds, compositions, kits, methods of synthesis, and methods of use, involving epipolythiodiketopiperazines and polythiodiketopiperazines.
Mohammad Movassaghi, Chase Robert Olsson, Tony Z. Scott, Jaime Cheah, Joshua Nathaniel Payette
Filed: 23 Dec 22
Utility
Facile Synthesis of Aluminum Salts Using Activated Aluminum Precursor
6 Jul 23
The present disclosure provides a method of producing an aluminum salt, comprising reacting activated aluminum metal (Al(0)) with an anion donor.
Jude Aaron Kelley, Alla Ostrinskaya, Eric Richard Morgan, Roderick Russell Kunz
Filed: 31 Oct 22
Utility
Splicing-dependent Transcriptional Gene Silencing or Activation
6 Jul 23
Disclosed herein are methods for inhibiting or activating the transcription of a gene of interest, or inhibiting or activating the transcription of specific mRNA isoforms of a gene by using antisense oligonucleotides and/or small molecules.
Christopher B. Burge, Ana Fiszbein
Filed: 13 Dec 22