1919 patents
Page 8 of 96
Utility
Dna-dye Assembly Based Single-molecule Fluorescence Lifetime Imaging Probes
21 Sep 23
Disclosed are nucleic acid-chromophores and nucleic acid assembly containing the nucleic acid-chromophores.
Stephanie Marie Hart, Xiao Wang, Mark Bathe, Gabriela S. Schlau-Cohen, Jiajia Guo
Filed: 31 Oct 22
Utility
Bilayer Component for a Lithium Battery
21 Sep 23
A component for a lithium battery including a first layer including a lithium garnet having a porosity of 0 percent to less than 25 percent, based on a total volume of the first layer; and a second layer on the first layer and having a porosity of 25 percent to 80 percent, based on a total volume of the second layer, wherein the second layer is on the first layer and the second layer has a composition that is different from a composition of the first layer.
Won Seok Chang, Zachary Hood, Jennifer Rupp, Lincoln Miara
Filed: 23 May 23
Utility
Vibrating Ingestible Capsule
14 Sep 23
The gastrointestinal capsule provides mechanical stimulation within the gastrointestinal tract.
Shriya Sruthi Srinivasan, Carlo Giovanni TRAVERSO, Robert S. LANGER, Amro A. Alshareef
Filed: 13 Mar 23
Utility
Ingestible Capsules
14 Sep 23
An ingestible capsule includes a housing forming a cavity and having a textured outer surface.
Shriya Sruthi Srinivasan, Carlo Giovanni TRAVERSO, Robert S. LANGER, Amro A. Alshareef
Filed: 13 Mar 23
Utility
Engineering and Optimization of Systems, Methods, Enzymes and Guide Scaffolds of CAS9 Orthologs and Variants for Sequence Manipulation
14 Sep 23
The invention provides for systems, methods, and compositions for altering expression of target gene sequences and related gene products.
Feng ZHANG, Winston YAN, Osamu NUREKI, Kaijie ZHENG, Le CONG, Hiroshi NISHIMASU, Fei RAN, Yinqing LI
Filed: 26 Jan 23
Utility
Cyclooctynes for Click Chemistry
14 Sep 23
Provided herein are dibenzocyclooctyne compounds useful as reagents in 1,3-dipolar cycloaddition reactions, and methods for their preparation.
Ronald T. Raines, Brian Gold, Jesús M. Dones, Nile S. Abularrage, Brian James Graham
Filed: 1 May 23
Utility
Reducing Bubble Accumulation on Electrodes, and Related Articles and Systems
14 Sep 23
Disclosed herein are methods for reducing bubble accumulation on electrodes.
Kripa K. Varanasi, John Lake
Filed: 2 Jun 21
Utility
Programmable Insertion Approaches Via Reverse Transcriptase Recruitment
14 Sep 23
This disclosure provides complexes for prime editing comprising an RNA-guided nuclease, a fusion protein comprising a reverse transcriptase domain linked to a nucleic acid binding protein, and a guide RNA (gRNA) comprising at least one protein-recruiting stem-loop nucleic acid sequence, wherein the protein-recruiting stem-loop nucleic acid sequence binds to the nucleic acid binding protein.
Omar Abudayyeh, Jonathan Gootenberg, Lukas Villiger, Kaiyi Jiang
Filed: 16 Dec 22
Utility
Guide-rna Expression System for a Host Cell
14 Sep 23
The present invention relates to the field of molecular biology and cell biology.
Eric Mosher YOUNG, Amar GHODASARA, René VERWAAL, Johannes Andries ROUBOS, Bianca Elisabeth Maria GIELESEN, Brenda VONK, Alec A.K. NIELSEN, Christopher Ashby VOIGT
Filed: 22 Mar 23
Utility
High-Speed Spatial Light Modulation and Quantum Control
14 Sep 23
An atom control architecture based on VIS-IR photonic integrated circuit (PIC) technology is characterized by (1) visible (VIS) and near-infrared (IR) wavelength operation, (2) channel counts extensible beyond 1000s of individually addressable atoms, (3) high intensity modulation extinction and (4) repeatability compatible with low gate errors, and (5) fast switching times.
Artur Hermans, Adrian Johannes Menssen, Christopher Louis Panuski, Ian Robert Christen, Dirk Robert ENGLUND
Filed: 10 Jan 23
Utility
Novel Cas Enzymes and Methods of Profiling Specificity and Activity
14 Sep 23
A method of identifying and characterizing novel Cas protein and guide RNAs with desired activity and specificity.
Feng Zhang, Jonathan Leo Schmid-Burgk, Linyi Gao, David Li
Filed: 11 Mar 21
Utility
Deep Reinforcement Learning-enabled Cryo-em Data Collection
14 Sep 23
Methods and systems for performing electron microscopy are provided.
Michael Cianfrocco, Quanfu Fan, Yilai Li, Seychelle Vos
Filed: 8 Mar 23
Utility
Systems and Methods for In-situ, Real-time Additive Manufacturing Analysis
14 Sep 23
Systems and methods for analyzing mechanical properties in-situ and in real-time of an object being additively manufactured are provided.
Cemal Cem TASAN, Gianluca ROSCIOLI
Filed: 15 Sep 21
Utility
Accelerated Synthesis of Nickle-Rich Cathode Materials Using Flame-Assisted Spray Pyrolysis
7 Sep 23
Methods of synthesis of nickel-rich cathode materials can include preheating droplets, decomposing the droplets in a burner, collecting solid particles, and calcinating the solid particles.
Sili Deng, Jianan Zhang, Valerie L Muldoon
Filed: 1 Mar 23
Utility
Systems and Methods for On-person Wearable Electronic Devices
7 Sep 23
Systems and methods are provided for on-person wearable electronic devices configured for extended periods of wear.
Xuanhe ZHAO, Xiaoyu CHEN, Chonghe WANG
Filed: 6 Mar 23
Utility
Methods and Systems for Solid Phase Peptide Synthesis
7 Sep 23
Methods and systems for control of solid phase peptide synthesis are generally described.
Dale Arlington Thomas, III, Alexander James Mijalis, Bradley L. Pentelute, Mark David Simon, Surin Mong
Filed: 20 Dec 22
Utility
Carrier-free Biologically-active Protein Nanostructures
7 Sep 23
The present disclosure provides compositions and methods for efficient and effective protein delivery in vitro and in vivo.
Li Tang, Darrell J. Irvine
Filed: 11 Nov 22
Utility
Magnet Structures Comprising a High Temperature Superconductor (HTS) Cable In Groove
7 Sep 23
A method includes inserting a high temperature superconductor (HTS) cable into a groove of a support structure; and flowing a molten metal into the HTS cable while the HTS cable is in the groove.
Alexey RADOVINSKY, Brian LABOMBARD, Robert MUMGAARD
Filed: 11 May 21
Utility
Systems, Methods, and Compositions for Site-specific Genetic Engineering Using Programmable Addition Via Site-specific Targeting Elements (Paste)
7 Sep 23
This disclosure provides systems, methods, and compositions for site-specific genetic engineering using Programmable Addition via Site-Specific Targeting Elements (PASTE).
Omar Abudayyeh, Jonathan Gootenberg
Filed: 14 Dec 22
Utility
Radio-Frequency Photonic Architecture for Deep Neural Networks, Signal Processing, and Computing
7 Sep 23
A multiplicative analog frequency transform optical neural network (MAFT-ONN) encodes data in the frequency domain, achieves matrix-vector products in a single shot using photoelectric multiplication, and uses a single electro-optic modulator for the nonlinear activation of all neurons in each layer.
Ronald A. Davis, Dirk Robert ENGLUND
Filed: 3 Jan 23