151 patents
Page 6 of 8
Utility
Composite Microneedle Array Including Nanostructures Thereon
18 Feb 21
Disclosed are composite microneedles arrays including microneedles and a film overlaying the microneedles.
Russell Frederick Ross
Filed: 23 Sep 20
Utility
Antigen binding proteins that bind PD-L1
16 Feb 21
There is disclosed anti-PD-L1 IgG class antibodies that have an improved ability to be manufactured at higher yields.
Heyue Zhou
Filed: 10 Oct 18
Utility
Fluid delivery apparatus having a gas extraction device and method of use
2 Feb 21
A gas extraction device for a fluid delivery apparatus includes a first layer and a vent membrane coupled to the first layer.
Russell F. Ross, Andrew T. Baker, Luke Hagan
Filed: 9 Jan 20
Utility
Drug-Conjugates With a Targeting Molecule and Two Different Drugs
21 Jan 21
There is disclosed an improved ADC (antibody drug conjugate) type composition having at least two different drug payloads conjugated to a single targeting protein.
Zhenwei Miao, Gang Chen, Tong Zhu, Alisher B. Khasanov, Yufeng Hong, Hong D. Zhang, Alexander Chucholowski
Filed: 29 Sep 20
Utility
Antibody Therapeutics that Bind CD38
23 Dec 20
There is disclosed compositions and methods relating to or derived from anti-CD38 antibodies.
Heyue Zhou, John Dixon Gray
Filed: 8 Sep 20
Utility
Dimeric Antigen Receptors
23 Dec 20
The present disclosure provides dimeric antigen receptors (DAR) constructs comprising a heavy chain binding region on one polypeptide chain and a light chain binding region on a separate polypeptide chain.
Henry Hongjun Ji, Wenzhong Guo, Yanliang Zhang, Gunnar F. Kaufmann, Bei Bei Ding
Filed: 3 Sep 20
Utility
ANTI-OX40 Binding Proteins
9 Dec 20
The present disclosure provides anti-OX40 antibodies, and antigen-binding portions thereof.
DAMIEN BRESSON
Filed: 16 Aug 20
Utility
Increased Bioavailability of Transdermally Delivered Agents
9 Dec 20
A method for delivering a bioactive agent to the cardiovascular system is described.
Russell F. Ross
Filed: 12 Aug 20
Utility
Drug-conjugates with a targeting molecule and two different drugs
16 Nov 20
There is disclosed an improved ADC (antibody drug conjugate) type composition having at least two different drug payloads conjugated to a single targeting protein.
Zhenwei Miao, Gang Chen, Tong Zhu, Alisher B. Khasanov, Yufeng Hong, Hong D. Zhang, Alexander Chucholowski
Filed: 14 Oct 14
Utility
Microneedle Array Assembly and Fluid Delivery Apparatus Having Such an Assembly
11 Nov 20
A microneedle array assembly includes a microneedle array that has a plurality of microneedles.
Andrew T. BAKER, Russell F. ROSS
Filed: 16 Apr 17
Utility
Medical Devices for Delivery of siRNA
4 Nov 20
Disclosed are medical devices that incorporate siRNA.
Russell Frederick Ross
Filed: 19 Jul 18
Utility
Methods for Lymphatic Delivery of Active Agents
28 Oct 20
The present invention concerns delivery of agents to the skin.
Russell F. Ross
Filed: 9 Jul 20
Utility
Use of oncolytic herpes simplex virus, alone or in combination with immune check-point inhibitor, in the treatment of cancer
26 Oct 20
An oncolytic herpes simplex virus is disclosed for use in a method of treating cancer, the method comprising administering one or more doses of an oncolytic herpes simplex virus effective to induce a Th1 immune response in the subject, and optionally administering a therapeutically effective amount of an immune checkpoint inhibitor.
Joe Conner
Filed: 18 Jan 18
Utility
Methods for better delivery of active agents to tumors
19 Oct 20
The present invention concerns delivery of agents through the skin.
Russell Frederick Ross
Filed: 21 Jul 16
Utility
Composite microneedle array including nanostructures thereon
19 Oct 20
Disclosed are composite microneedles arrays including microneedles and a film overlaying the microneedles.
Russell Frederick Ross
Filed: 19 Jul 18
Utility
Disulfide bridging conjugates
12 Oct 20
James T. Patterson, Gunnar F. Kaufmann, Yanwen Fu, Tong Zhu
Filed: 31 Jul 18
Utility
Antibody therapeutics that bind CD38
12 Oct 20
There is disclosed compositions and methods relating to or derived from anti-CD38 antibodies.
Heyue Zhou, John Dixon Gray
Filed: 3 Aug 18
Utility
Device for Delivery of Rheumatoid Arthritis Medication
23 Sep 20
Disclosed are devices for delivering a rheumatoid arthritis drug across a dermal barrier.
Russell Frederick Ross
Filed: 8 Jun 20
Utility
Anti-OX40 binding proteins
21 Sep 20
The present disclosure provides anti-OX40 antibodies, and antigen-binding portions thereof.
Damien Bresson
Filed: 6 Aug 17
Utility
Oncolytic Herpes Simplex Virus Infected Cells
16 Sep 20
A monocyte, monocyte derived cell or macrophage infected with an oncolytic herpes simplex virus is disclosed together with uses of such infected cells in the treatment of diseases such as cancer.
Joe Conner, Munitta Muthana, Claire Elizabeth Lewis
Filed: 12 Feb 20