747 patents
Page 2 of 38
Utility
Wearable Air Pollutant Monitoring Device
7 Dec 23
Wearable pollutant monitoring devices, associated methods of manufacture, and methods for pollution analysis are described herein.
Krystal Pollitt, Elizabeth Lin, Jeremy Koelmel
Filed: 3 Sep 21
Utility
Cytoplasmic incompatibility factors and methods for controlling anthropods
5 Dec 23
The disclosure relates to genetically modified bacteria, genetically modified arthropods, and methods for controlling and/or reducing arthropod populations.
Jason Metcalf, Seth R. Bordenstein, Daniel Lepage, Sarah Bordenstein, Mark Hochstrasser, John F. Beckmann, Judith Ronau
Filed: 9 Jun 17
Utility
Imide-based modulators of proteolysis and associated methods of use
5 Dec 23
The description relates to imide-based compounds, including bifunctional compounds comprising the same, which find utility as modulators of targeted ubiquitination, especially inhibitors of a variety of polypeptides and other proteins which are degraded and/or otherwise inhibited by bifunctional compounds according to the present invention.
Craig M. Crews, George Burslem, Philipp M. Cromm, Saul Jaime-Figueroa, Momar Toure
Filed: 17 Dec 21
Utility
Compositions and methods for scarless genome editing
5 Dec 23
The present invention includes compositions and methods for promoting scarless genome editing in a cell.
Murat Acar, Gregory Elison
Filed: 8 Nov 17
Utility
Rapidly synthesized extracellular matrix-based gels and patterning techniques, from micro- to macro-scale
30 Nov 23
In some aspects, the present invention provides a method of forming crowded collagen based constructs, having the steps of providing a collagen solution in a buffer, providing a macromolecular bath solution, and delivering the collagen solution into the macromolecular bath solution to form crowded collagen constructs.
Michael Mak, Xiangyu Gong
Filed: 15 May 23
Utility
Compounds and Methods for Treating or Preventing Anterior Segment Ocular Disorders and/or Retinal Degenerations
30 Nov 23
The invention provides a method of treating retinal degenerations, such as but not limited to anterior segment ocular disorders and/or age-related macular degeneration (AMD), in a subject, the method comprising administering to the subject a pharmaceutical composition comprising an effective amount of a compound of formula (1) or formula (2).
Mark Fields, Lucian Del Priore, Huey Cai, Denton Hoyer
Filed: 12 Jun 23
Utility
Hyperbranched polyglycerol-coated particles and methods of making and using thereof
28 Nov 23
Core-shell particles and methods of making and using thereof are described herein.
Yang Deng, Asiri Ediriwickrema, W. Mark Saltzman
Filed: 22 May 20
Utility
Compositions and Methods of Treating or Preventing Fibrotic Lung Diseases
23 Nov 23
The invention includes a method of preventing or treating a fibrotic lung disease in a subject, comprising administering to the subject a thyroid receptor β-agonist.
Naftali Kaminski, Guoying Yu, Argyrios Tzouvelekis
Filed: 14 Apr 23
Utility
All-optical Visualization of Specific Molecules In the Ultrastructural Context of Brain Tissue
16 Nov 23
One aspect of the invention provides a method for preparing a biological sample.
Ons M'Saad, Joerg Bewersdorf
Filed: 4 Apr 23
Utility
Methods of Treating or Preventing Acute Respiratory Distress Syndrome
16 Nov 23
The invention includes a method of preventing or treating acute respiratory distress syndrome (ARDS) in a subject, comprising administering to the subject a thyroid hormone and/or a thyroid receptor β-agonist.
Naftali Kaminski, Patty Lee, Guoying Yu, Yi Zhang
Filed: 13 Jan 23
Utility
Compounds and Compositions for Disrupting Programmed Ribosomal Frameshifting
16 Nov 23
In one aspect, the present disclosure relates to a pyrrolidine substituted quinolone compound.
Junjie Guo, Yu Sun
Filed: 23 Aug 21
Utility
Selective Agonists of 5-HT2A Receptor and Methods of Use
16 Nov 23
In one aspect, the present disclosure describes tetrahydropyridine compounds of formula (I), which are 5-HT2A receptor agonists that exhibit selective binding to the 5-HT2A receptor over the 5-HT2B receptor.
Jonathan Ellman, Danielle Confair, Oh Sang Kweon, Bryan Roth, Kuglae Kim, Brian Shoichet, Anat Levit, John Irwin
Filed: 27 Sep 21
Utility
Poly(amine-co-ester) polymers and polyplexes with modified end groups and methods of use thereof
14 Nov 23
Poly(amine-co-ester) polymers, methods of forming active agent-load polyplexes and particles therefrom, and methods of using them for delivery of nucleic acid agents with optimal uptake have been developed.
W. Mark Saltzman, Yuhang Jiang
Filed: 29 Apr 20
Utility
Systems and methods of formal verification
14 Nov 23
Systems and methods for formal verification of programs.
Zhong Shao, Ronghui Gu, Vilhelm Sjoberg, Jieung Kim, Jeremie Koenig
Filed: 12 Jul 22
Utility
INTERLEUKIN-18 Variants and Methods of Use
9 Nov 23
The present invention provides compositions and methods comprising an activator of IL-18 activity for use in therapeutic and non-therapeutic applications.
Aaron Ring, Ting Zhou, Suzanne Fischer
Filed: 8 Mar 23
Utility
Immunotherapy of Skin Cancer Using Mpla-loaded HPG Nanoparticles
9 Nov 23
Encapsulation of MPLA in HPG-PLA nanoparticles having bioadhesive functional groups on the surface (“BNPs”) prolongs the local antitumor immune response in melanoma and boosts the adaptive immune response conferred by MPLA due to the polymer's bioadhesive properties.
Kwangsoo Shin, Jungsoo Chang, W. Mark Saltzman, Michael Girardi
Filed: 9 May 23
Utility
Reverse Transcriptase and Methods of Use
9 Nov 23
The present invention provides compositions, methods, and kits related to reverse transcriptases derived from E.r. maturase.
Anna Marie Pyle, Chen Zhao
Filed: 12 Apr 23
Utility
Rapid Extracellular Antibody Profiling (Reap) for the Discovery and Use of Said Antibodies
9 Nov 23
The present invention relates to methods for a sensitive and high-throughput detection of various antibodies and targets thereof.
Connor Rosen, Eric Wang, Aaron Ring, Yile Dai
Filed: 22 Mar 21
Utility
System and Method for Removing Carbon Dioxide from Sea Water
9 Nov 23
Disclosed herein is a system for removing carbon dioxide (CO2) from seawater including an electrodialysis flow cell comprising a bipolar membrane having an acidified seawater product stream with a pH less than or equal to 8.5 and a basified seawater product stream with a pH greater than or equal to 9.0; a photobioreactor; and a microbially induced carbonate precipitation component; wherein the electrodialysis flow cell is in fluid communication with the photobioreactor via the acidified seawater product stream and in fluid communication with the microbially induced carbonate precipitation component via the basified seawater product stream.
Shu Hu, Atsu Kludze, Marcelo Lejeune
Filed: 5 May 23
Utility
Method of Treating, Ameliorating And/or Preventing Depression
2 Nov 23
Described herein is a method for treating, ameliorating, and/or preventing depression in a subject in need thereof.
Deepak Cyril D’Souza
Filed: 27 Apr 23