PROFUND VP BIOTECHNOLOGY

Fund Profile

Fund profile

Fund manager

Profunds

Total assets

$36.52 mm

Liabilities

$369.86 k

Net assets

$36.15 mm

Number of holdings

145.00

145 Holdings

As of Dec 2024

Security	$Holding	Balance	% of Fund	Category	Position	Country
NBIX Neurocrine Biosciences, Inc.	917.96 k	6.73 k shares	2.54	Common equity	Long	USA
ABBV AbbVie Inc.	878.73 k	4.95 k shares	2.43	Common equity	Long	USA
GILD Gilead Sciences, Inc.	862.18 k	9.33 k shares	2.39	Common equity	Long	USA
BMRN BioMarin Pharmaceutical Inc.	859.16 k	13.07 k shares	2.38	Common equity	Long	USA
UTHR United Therapeutics Corporation	840.11 k	2.38 k shares	2.32	Common equity	Long	USA
BIIB Biogen Inc.	837.39 k	5.48 k shares	2.32	Common equity	Long	USA
MRNA Moderna, Inc.	836.55 k	20.12 k shares	2.31	Common equity	Long	USA
SRPT Sarepta Therapeutics, Inc.	836.17 k	6.88 k shares	2.31	Common equity	Long	USA
AMGN Amgen Inc.	821.80 k	3.15 k shares	2.27	Common equity	Long	USA
INCY Incyte Corporation	821.66 k	11.90 k shares	2.27	Common equity	Long	USA
NTRA Natera, Inc.	816.83 k	5.16 k shares	2.26	Common equity	Long	USA
INSM Insmed Incorporated	802.31 k	11.62 k shares	2.22	Common equity	Long	USA
ALNY Alnylam Pharmaceuticals, Inc.	798.41 k	3.39 k shares	2.21	Common equity	Long	USA
REGN Regeneron Pharmaceuticals, Inc.	794.96 k	1.12 k shares	2.20	Common equity	Long	USA
PCVX Vaxcyte, Inc.	775.30 k	9.47 k shares	2.14	Common equity	Long	USA
EXAS Exact Sciences Corporation	767.16 k	13.65 k shares	2.12	Common equity	Long	USA
VRTX Vertex Pharmaceuticals Incorporated	741.77 k	1.84 k shares	2.05	Common equity	Long	USA
VKTX Viking Therapeutics, Inc.	700.94 k	17.42 k shares	1.94	Common equity	Long	USA
HALO Halozyme Therapeutics, Inc.	664.85 k	13.91 k shares	1.84	Common equity	Long	USA
MDGL Madrigal Pharmaceuticals, Inc.	656.64 k	2.13 k shares	1.82	Common equity	Long	USA
TGTX TG Therapeutics, Inc.	640.77 k	21.29 k shares	1.77	Common equity	Long	USA
Invesco Government & Agency Portfolio	574.37 k	574.37 k shares	1.59	Short-term investment vehicle	Long	USA
ADMA ADMA Biologics, Inc.	565.28 k	32.96 k shares	1.56	Common equity	Long	USA
ROIV Roivant Sciences Ltd.	541.52 k	45.78 k shares	1.50	Common equity	Long	Bermuda
IONS Ionis Pharmaceuticals, Inc.	532.97 k	15.25 k shares	1.47	Common equity	Long	USA
CYTK Cytokinetics, Incorporated	499.33 k	10.62 k shares	1.38	Common equity	Long	USA
BPMC Blueprint Medicines Corporation	498.03 k	5.71 k shares	1.38	Common equity	Long	USA
APLS Apellis Pharmaceuticals, Inc.	494.96 k	15.51 k shares	1.37	Common equity	Long	USA
RVMD Revolution Medicines, Inc.	485.47 k	11.10 k shares	1.34	Common equity	Long	USA
EXEL Exelixis, Inc.	453.11 k	13.61 k shares	1.25	Common equity	Long	USA
BBIO BridgeBio Pharma, Inc.	441.07 k	16.07 k shares	1.22	Common equity	Long	USA
CRSP CRISPR Therapeutics AG	419.22 k	10.65 k shares	1.16	Common equity	Long	Switzerland
Alkermes Plc	387.20 k	13.46 k shares	1.07	Common equity	Long	Ireland
SMMT Summit Therapeutics Inc.	357.29 k	20.02 k shares	0.99	Common equity	Long	USA
ACLX Arcellx, Inc.	349.94 k	4.56 k shares	0.97	Common equity	Long	USA
RNA Avidity Biosciences, Inc.	330.58 k	11.37 k shares	0.91	Common equity	Long	USA
BHVN Biohaven Ltd.	324.50 k	8.69 k shares	0.90	Common equity	Long	Virgin Islands (British)
NUVL Nuvalent, Inc.	298.09 k	3.81 k shares	0.82	Common equity	Long	USA
SWTX SpringWorks Therapeutics, Inc.	285.35 k	7.90 k shares	0.79	Common equity	Long	USA
TWST Twist Bioscience Corporation	278.59 k	6.00 k shares	0.77	Common equity	Long	USA
RARE Ultragenyx Pharmaceutical Inc.	273.75 k	6.51 k shares	0.76	Common equity	Long	USA
GERN Geron Corporation	273.69 k	77.31 k shares	0.76	Common equity	Long	USA
KRYS Krystal Biotech, Inc.	273.69 k	1.75 k shares	0.76	Common equity	Long	USA
CRNX Crinetics Pharmaceuticals, Inc.	266.85 k	5.22 k shares	0.74	Common equity	Long	USA
IOVA Iovance Biotherapeutics, Inc.	263.40 k	35.59 k shares	0.73	Common equity	Long	USA
RXRX Recursion Pharmaceuticals, Inc.	258.56 k	38.25 k shares	0.72	Common equity	Long	USA
DYN Dyne Therapeutics, Inc.	253.46 k	10.76 k shares	0.70	Common equity	Long	USA
CLDX Celldex Therapeutics, Inc.	247.47 k	9.79 k shares	0.68	Common equity	Long	USA
VERA Vera Therapeutics, Inc.	238.22 k	5.63 k shares	0.66	Common equity	Long	USA
PTGX Protagonist Therapeutics, Inc.	236.73 k	6.13 k shares	0.65	Common equity	Long	USA
VCYT Veracyte, Inc.	229.88 k	5.81 k shares	0.64	Common equity	Long	USA
PTCT PTC Therapeutics, Inc.	226.24 k	5.01 k shares	0.63	Common equity	Long	USA
SRRK Scholar Rock Holding Corporation	216.79 k	5.02 k shares	0.60	Common equity	Long	USA
VRDN Viridian Therapeutics, Inc.	212.98 k	11.11 k shares	0.59	Common equity	Long	USA
DVAX Dynavax Technologies Corporation	204.38 k	16.01 k shares	0.57	Common equity	Long	USA
FOLD Amicus Therapeutics, Inc.	201.73 k	21.42 k shares	0.56	Common equity	Long	USA
TVTX Travere Therapeutics, Inc.	197.42 k	11.33 k shares	0.55	Common equity	Long	USA
IDYA IDEAYA Biosciences, Inc.	195.19 k	7.60 k shares	0.54	Common equity	Long	USA
SLNO Soleno Therapeutics, Inc.	191.94 k	4.27 k shares	0.53	Common equity	Long	USA
NTLA Intellia Therapeutics, Inc.	191.14 k	16.39 k shares	0.53	Common equity	Long	USA
ARQT Arcutis Biotherapeutics, Inc.	188.21 k	13.51 k shares	0.52	Common equity	Long	USA
IMVT Immunovant, Inc.	185.55 k	7.49 k shares	0.51	Common equity	Long	USA
NVAX Novavax, Inc.	185.00 k	23.01 k shares	0.51	Common equity	Long	USA
DNLI Denali Therapeutics Inc.	184.99 k	9.08 k shares	0.51	Common equity	Long	USA
RYTM Rhythm Pharmaceuticals, Inc.	181.21 k	3.24 k shares	0.50	Common equity	Long	USA
JANX Janux Therapeutics, Inc.	179.41 k	3.35 k shares	0.50	Common equity	Long	USA
ACAD ACADIA Pharmaceuticals Inc.	177.08 k	9.65 k shares	0.49	Common equity	Long	USA
BEAM Beam Therapeutics Inc.	176.97 k	7.14 k shares	0.49	Common equity	Long	USA
ARDX Ardelyx, Inc.	174.14 k	34.35 k shares	0.48	Common equity	Long	USA
APGE Apogee Therapeutics, Inc.	167.79 k	3.70 k shares	0.46	Common equity	Long	USA
PRAX Praxis Precision Medicines, Inc.	166.23 k	2.16 k shares	0.46	Common equity	Long	USA
CDNA CareDx, Inc	164.75 k	7.70 k shares	0.46	Common equity	Long	USA
ARWR Arrowhead Pharmaceuticals, Inc.	163.67 k	8.71 k shares	0.45	Common equity	Long	USA
CPRX Catalyst Pharmaceuticals, Inc.	156.96 k	7.52 k shares	0.43	Common equity	Long	USA
SNDX Syndax Pharmaceuticals, Inc.	151.29 k	11.44 k shares	0.42	Common equity	Long	USA
AGIO Agios Pharmaceuticals, Inc.	148.43 k	4.52 k shares	0.41	Common equity	Long	USA
VCEL Vericel Corporation	147.05 k	2.68 k shares	0.41	Common equity	Long	USA
KYMR Kymera Therapeutics, Inc.	147.00 k	3.65 k shares	0.41	Common equity	Long	USA
MYGN Myriad Genetics, Inc.	146.30 k	10.67 k shares	0.40	Common equity	Long	USA
CGON CG Oncology, Inc. Common stock	145.03 k	5.06 k shares	0.40	Common equity	Long	USA
NRIX Nurix Therapeutics, Inc.	140.60 k	7.46 k shares	0.39	Common equity	Long	USA
AKRO Akero Therapeutics, Inc.	129.75 k	4.66 k shares	0.36	Common equity	Long	USA
DAWN Day One Biopharmaceuticals, Inc.	129.74 k	10.24 k shares	0.36	Common equity	Long	USA
MNKD MannKind Corporation	128.68 k	20.01 k shares	0.36	Common equity	Long	USA
RCKT Rocket Pharmaceuticals, Inc.	126.18 k	10.04 k shares	0.35	Common equity	Long	USA
MIRM Mirum Pharmaceuticals, Inc.	119.96 k	2.90 k shares	0.33	Common equity	Long	USA
SYRE Spyre Therapeutics, Inc.	114.75 k	4.93 k shares	0.32	Common equity	Long	USA
BCRX BioCryst Pharmaceuticals, Inc.	113.43 k	15.08 k shares	0.31	Common equity	Long	USA
IRON Disc Medicine, Inc.	112.98 k	1.78 k shares	0.31	Common equity	Long	USA
CAPR Capricor Therapeutics, Inc.	111.97 k	8.11 k shares	0.31	Common equity	Long	USA
SPRY ARS Pharmaceuticals, Inc.	95.12 k	9.02 k shares	0.26	Common equity	Long	USA
IBRX ImmunityBio, Inc.	90.43 k	35.32 k shares	0.25	Common equity	Long	USA
EBS Emergent BioSolutions Inc.	88.87 k	9.30 k shares	0.25	Common equity	Long	USA
CDMO Avid Bioservices, Inc.	83.29 k	6.74 k shares	0.23	Common equity	Long	USA
KURA Kura Oncology, Inc.	81.46 k	9.35 k shares	0.23	Common equity	Long	USA
COGT Cogent Biosciences, Inc.	80.60 k	10.33 k shares	0.22	Common equity	Long	USA
XNCR Xencor, Inc.	76.71 k	3.34 k shares	0.21	Common equity	Long	USA
HUMA Humacyte, Inc.	74.95 k	14.84 k shares	0.21	Common equity	Long	USA
RCUS Arcus Biosciences, Inc.	74.30 k	4.99 k shares	0.21	Common equity	Long	USA
ALT Altimmune, Inc.	73.06 k	10.13 k shares	0.20	Common equity	Long	USA
HSBC SECURITIES (USA), INC. B 4.2 , 1/01/2024	72.00 k	72.00 k principal	0.20	Repurchase agreement	Long	USA
ANNX Annexon, Inc.	71.95 k	14.03 k shares	0.20	Common equity	Long	USA
CGEM Cullinan Oncology, Inc.	70.14 k	5.76 k shares	0.19	Common equity	Long	USA
PRTA Prothena Corporation plc	69.10 k	4.99 k shares	0.19	Common equity	Long	Ireland
IRWD Ironwood Pharmaceuticals, Inc.	67.36 k	15.21 k shares	0.19	Common equity	Long	USA
RLAY Relay Therapeutics, Inc.	66.04 k	16.03 k shares	0.18	Common equity	Long	USA
GRAL GRAIL, Inc.	64.10 k	3.59 k shares	0.18	Common equity	Long	USA
SOCIETE' GENERALE C 4.3 , 1/01/2024	64.00 k	64.00 k principal	0.18	Repurchase agreement	Long	USA
Arcturus Therapeutics Holdings, Inc.	62.77 k	3.70 k shares	0.17	Common equity	Long	USA
ANAB AnaptysBio, Inc.	60.28 k	4.55 k shares	0.17	Common equity	Long	USA
REPL Replimune Group, Inc.	60.14 k	4.97 k shares	0.17	Common equity	Long	USA
VIR Vir Biotechnology, Inc.	56.91 k	7.75 k shares	0.16	Common equity	Long	USA
IMNM Immunome, Inc.	55.51 k	5.23 k shares	0.15	Common equity	Long	USA
AVXL Anavex Life Sciences Corp.	51.47 k	4.79 k shares	0.14	Common equity	Long	USA
ALLO Allogene Therapeutics, Inc.	50.27 k	23.60 k shares	0.14	Common equity	Long	USA
VERV Verve Therapeutics, Inc.	49.42 k	8.76 k shares	0.14	Common equity	Long	USA
STOK Stoke Therapeutics, Inc.	47.64 k	4.32 k shares	0.13	Common equity	Long	USA
ArriVent Biopharma Inc	46.70 k	1.75 k shares	0.13	Common equity	Long	USA
RGNX REGENXBIO Inc.	46.58 k	6.03 k shares	0.13	Common equity	Long	USA
KROS Keros Therapeutics, Inc.	46.56 k	2.94 k shares	0.13	Common equity	Long	USA
NATWEST MARKETS PLC 4.33 , 1/01/2024	46.00 k	46.00 k principal	0.13	Repurchase agreement	Long	USA
ETNB 89bio, Inc.	44.57 k	5.70 k shares	0.12	Common equity	Long	USA
DNTH Dianthus Therapeutics, Inc.	39.85 k	1.83 k shares	0.11	Common equity	Long	USA
TRML Tourmaline Bio, Inc.	38.88 k	1.92 k shares	0.11	Common equity	Long	USA
CREDIT AGRICOLE CIB NY A 4.3 , 1/01/2024	38.00 k	38.00 k principal	0.11	Repurchase agreement	Long	USA
ERAS Erasca, Inc.	33.82 k	13.47 k shares	0.09	Common equity	Long	USA
LENZ LENZ Therapeutics, Inc.	32.88 k	1.14 k shares	0.09	Common equity	Long	USA
SANA Sana Biotechnology, Inc.	32.86 k	20.16 k shares	0.09	Common equity	Long	USA
MDXG MiMedx Group, Inc.	31.05 k	3.23 k shares	0.09	Common equity	Long	USA
UMB FINANCIAL CORP. 4.15 , 1/01/2024	31.00 k	31.00 k principal	0.09	Repurchase agreement	Long	USA
ABUS Arbutus Biopharma Corporation	30.83 k	9.43 k shares	0.09	Common equity	Long	Canada
OLMA Olema Pharmaceuticals, Inc.	30.49 k	5.23 k shares	0.08	Common equity	Long	USA
CRGX CARGO Therapeutics, Inc. Common Stock	30.38 k	2.11 k shares	0.08	Common equity	Long	USA
KalVista Pharmaceuticals, Inc.	29.63 k	3.50 k shares	0.08	Common equity	Long	USA
SVRA Savara Inc.	28.99 k	9.44 k shares	0.08	Common equity	Long	USA
TSHA Taysha Gene Therapies, Inc.	28.03 k	16.20 k shares	0.08	Common equity	Long	USA
ORIC ORIC Pharmaceuticals, Inc.	26.64 k	3.30 k shares	0.07	Common equity	Long	USA
CELC Celcuity Inc.	25.96 k	1.98 k shares	0.07	Common equity	Long	USA
ROYAL BANK OF CANADA 4.28 , 1/01/2024	25.00 k	25.00 k principal	0.07	Repurchase agreement	Long	USA
SGMO Sangamo Therapeutics, Inc.	23.02 k	22.57 k shares	0.06	Common equity	Long	USA
AKBA Akebia Therapeutics, Inc.	21.94 k	11.55 k shares	0.06	Common equity	Long	USA
ATXS Astria Therapeutics, Inc.	21.57 k	2.41 k shares	0.06	Common equity	Long	USA
YMAB Y-mAbs Therapeutics, Inc.	20.75 k	2.65 k shares	0.06	Common equity	Long	USA
GLUE Monte Rosa Therapeutics, Inc.	12.34 k	1.78 k shares	0.03	Common equity	Long	USA
VPBT_SPSIBI_GOLDMAN GOLDMAN SACHS GROUP, INC.	-5.54 k	38.00 other units	-0.02	Equity derivative	Long	USA