Principal Healthcare Innovators ETF

Fund Profile

Fund profile

Tickers

BTEC

Fund manager

Principal Exchange-Traded Funds

Total assets

$16.49 mm

Liabilities

$51.71 k

Net assets

$16.44 mm

Number of holdings

268.00

BTEC stock data

1M 3M 6M 1Y

Top 200 of 268 Holdings

As of Jun 2024

Security	$Holding	Balance	% of Fund	Category	Position	Country
ALNY Alnylam Pharmaceuticals, Inc.	854.63 k	3.52 k shares	5.20	Common equity	Long	USA
MRNA Moderna, Inc.	588.41 k	4.96 k shares	3.58	Common equity	Long	USA
SRPT Sarepta Therapeutics, Inc.	524.56 k	3.32 k shares	3.19	Common equity	Long	USA
NTRA Natera, Inc.	463.59 k	4.28 k shares	2.82	Common equity	Long	USA
ILMN Illumina, Inc.	401.45 k	3.85 k shares	2.44	Common equity	Long	USA
CTLT Catalent, Inc.	360.60 k	6.41 k shares	2.19	Common equity	Long	USA
INSM Insmed Incorporated	357.98 k	5.34 k shares	2.18	Common equity	Long	USA
Roivant Sciences Ltd.	303.23 k	28.69 k shares	1.84	Common equity	Long	Bermuda
PCVX Vaxcyte, Inc.	289.66 k	3.84 k shares	1.76	Common equity	Long	USA
EXAS Exact Sciences Corporation	271.75 k	6.43 k shares	1.65	Common equity	Long	USA
CERE Cerevel Therapeutics Holdings Inc	262.60 k	6.42 k shares	1.60	Common equity	Long	USA
ELAN Elanco Animal Health Incorporated	253.43 k	17.56 k shares	1.54	Common equity	Long	USA
IONS Ionis Pharmaceuticals, Inc.	246.78 k	5.18 k shares	1.50	Common equity	Long	USA
BPMC Blueprint Medicines Corporation	236.68 k	2.20 k shares	1.44	Common equity	Long	USA
ITCI Intra-Cellular Therapies, Inc.	235.06 k	3.43 k shares	1.43	Common equity	Long	USA
RVMD Revolution Medicines, Inc.	227.58 k	5.86 k shares	1.38	Common equity	Long	USA
GKOS Glaukos Corporation	209.01 k	1.77 k shares	1.27	Common equity	Long	USA
VKTX Viking Therapeutics, Inc.	204.57 k	3.86 k shares	1.24	Common equity	Long	USA
MDGL Madrigal Pharmaceuticals, Inc.	201.15 k	718.00 shares	1.22	Common equity	Long	USA
SMMT Summit Therapeutics Inc.	199.81 k	25.62 k shares	1.22	Common equity	Long	USA
CYTK Cytokinetics, Incorporated	197.65 k	3.65 k shares	1.20	Common equity	Long	USA
TMDX TransMedics Group, Inc.	181.35 k	1.20 k shares	1.10	Common equity	Long	USA
BBIO BridgeBio Pharma, Inc.	166.16 k	6.56 k shares	1.01	Common equity	Long	USA
APLS Apellis Pharmaceuticals, Inc.	163.87 k	4.27 k shares	1.00	Common equity	Long	USA
NUVL Nuvalent, Inc.	159.53 k	2.10 k shares	0.97	Common equity	Long	USA
IBRX ImmunityBio, Inc.	153.79 k	24.33 k shares	0.94	Common equity	Long	USA
INSP Inspire Medical Systems, Inc.	142.26 k	1.06 k shares	0.87	Common equity	Long	USA
AXSM Axsome Therapeutics, Inc.	137.57 k	1.71 k shares	0.84	Common equity	Long	USA
IMVT Immunovant, Inc.	137.49 k	5.21 k shares	0.84	Common equity	Long	USA
CRNX Crinetics Pharmaceuticals, Inc.	126.26 k	2.82 k shares	0.77	Common equity	Long	USA
RNA Avidity Biosciences, Inc.	122.71 k	3.00 k shares	0.75	Common equity	Long	USA
RARE Ultragenyx Pharmaceutical Inc.	122.23 k	2.97 k shares	0.74	Common equity	Long	USA
IRTC iRhythm Technologies, Inc.	120.45 k	1.12 k shares	0.73	Common equity	Long	USA
DNLI Denali Therapeutics Inc.	118.31 k	5.10 k shares	0.72	Common equity	Long	USA
ARWR Arrowhead Pharmaceuticals, Inc.	116.64 k	4.49 k shares	0.71	Common equity	Long	USA
PRCT PROCEPT BioRobotics Corporation	114.73 k	1.88 k shares	0.70	Common equity	Long	USA
AZTA Azenta, Inc.	106.56 k	2.03 k shares	0.65	Common equity	Long	USA
TWST Twist Bioscience Corporation	106.30 k	2.16 k shares	0.65	Common equity	Long	USA
FOLD Amicus Therapeutics, Inc.	106.25 k	10.71 k shares	0.65	Common equity	Long	USA
DYN Dyne Therapeutics, Inc.	105.98 k	3.00 k shares	0.64	Common equity	Long	USA
ICUI ICU Medical, Inc.	105.57 k	889.00 shares	0.64	Common equity	Long	USA
ACLX Arcellx, Inc.	105.36 k	1.91 k shares	0.64	Common equity	Long	USA
NARI Inari Medical, Inc.	103.43 k	2.15 k shares	0.63	Common equity	Long	USA
Biohaven Ltd.	101.94 k	2.94 k shares	0.62	Common equity	Long	Virgin Islands (British)
TGTX TG Therapeutics, Inc.	101.47 k	5.70 k shares	0.62	Common equity	Long	USA
SWTX SpringWorks Therapeutics, Inc.	100.47 k	2.67 k shares	0.61	Common equity	Long	USA
ADMA ADMA Biologics, Inc.	98.38 k	8.80 k shares	0.60	Common equity	Long	USA
TNDM Tandem Diabetes Care, Inc.	97.42 k	2.42 k shares	0.59	Common equity	Long	USA
IDYA IDEAYA Biosciences, Inc.	95.18 k	2.71 k shares	0.58	Common equity	Long	USA
AGIO Agios Pharmaceuticals, Inc.	92.62 k	2.15 k shares	0.56	Common equity	Long	USA
RYTM Rhythm Pharmaceuticals, Inc.	91.77 k	2.24 k shares	0.56	Common equity	Long	USA
ENOV Enovis Corporation	89.77 k	1.99 k shares	0.55	Common equity	Long	USA
CLDX Celldex Therapeutics, Inc.	88.53 k	2.39 k shares	0.54	Common equity	Long	USA
GERN Geron Corporation	87.97 k	20.75 k shares	0.54	Common equity	Long	USA
PTCT PTC Therapeutics, Inc.	86.79 k	2.84 k shares	0.53	Common equity	Long	USA
RXST RxSight, Inc.	84.54 k	1.41 k shares	0.51	Common equity	Long	USA
MYGN Myriad Genetics, Inc.	83.38 k	3.41 k shares	0.51	Common equity	Long	USA
VCEL Vericel Corporation	82.40 k	1.80 k shares	0.50	Common equity	Long	USA
JANX Janux Therapeutics, Inc.	81.52 k	1.95 k shares	0.50	Common equity	Long	USA
IOVA Iovance Biotherapeutics, Inc.	80.75 k	10.07 k shares	0.49	Common equity	Long	USA
NTLA Intellia Therapeutics, Inc.	79.94 k	3.57 k shares	0.49	Common equity	Long	USA
CGON CG Oncology, Inc. Common stock	77.69 k	2.46 k shares	0.47	Common equity	Long	USA
PTGX Protagonist Therapeutics, Inc.	77.37 k	2.23 k shares	0.47	Common equity	Long	USA
NVAX Novavax, Inc.	75.48 k	5.96 k shares	0.46	Common equity	Long	USA
TXG 10x Genomics, Inc.	74.61 k	3.84 k shares	0.45	Common equity	Long	USA
VERA Vera Therapeutics, Inc.	74.46 k	2.06 k shares	0.45	Common equity	Long	USA
RCKT Rocket Pharmaceuticals, Inc.	72.90 k	3.39 k shares	0.44	Common equity	Long	USA
BEAM Beam Therapeutics Inc.	71.18 k	3.04 k shares	0.43	Common equity	Long	USA
Novocure Ltd.	69.94 k	4.08 k shares	0.43	Common equity	Long	Jersey
KYMR Kymera Therapeutics, Inc.	68.15 k	2.28 k shares	0.41	Common equity	Long	USA
ARVN Arvinas, Inc.	67.19 k	2.52 k shares	0.41	Common equity	Long	USA
SNDX Syndax Pharmaceuticals, Inc.	65.92 k	3.21 k shares	0.40	Common equity	Long	USA
MORF Morphic Holding, Inc.	65.24 k	1.92 k shares	0.40	Common equity	Long	USA
APGE Apogee Therapeutics, Inc.	64.10 k	1.63 k shares	0.39	Common equity	Long	USA
ARDX Ardelyx, Inc.	63.60 k	8.58 k shares	0.39	Common equity	Long	USA
EWTX Edgewise Therapeutics, Inc.	61.81 k	3.43 k shares	0.38	Common equity	Long	USA
KROS Keros Therapeutics, Inc.	61.47 k	1.35 k shares	0.37	Common equity	Long	USA
MIRM Mirum Pharmaceuticals, Inc.	60.93 k	1.78 k shares	0.37	Common equity	Long	USA
VCYT Veracyte, Inc.	60.20 k	2.78 k shares	0.37	Common equity	Long	USA
AKRO Akero Therapeutics, Inc.	59.52 k	2.54 k shares	0.36	Common equity	Long	USA
RXRX Recursion Pharmaceuticals, Inc.	58.97 k	7.86 k shares	0.36	Common equity	Long	USA
KURA Kura Oncology, Inc.	58.15 k	2.82 k shares	0.35	Common equity	Long	USA
NMRA Neumora Therapeutics, Inc. Common Stock	56.73 k	5.77 k shares	0.35	Common equity	Long	USA
ATEC Alphatec Holdings, Inc.	52.79 k	5.05 k shares	0.32	Common equity	Long	USA
RCUS Arcus Biosciences, Inc.	51.05 k	3.35 k shares	0.31	Common equity	Long	USA
BCRX BioCryst Pharmaceuticals, Inc.	49.22 k	7.96 k shares	0.30	Common equity	Long	USA
State Street Institutional U.S. Government Money Market Fund Premier Class	48.95 k	48.95 k shares	0.30	Short-term investment vehicle	Long	USA
SANA Sana Biotechnology, Inc.	45.27 k	8.29 k shares	0.28	Common equity	Long	USA
VIR Vir Biotechnology, Inc.	45.15 k	5.07 k shares	0.27	Common equity	Long	USA
DAWN Day One Biopharmaceuticals, Inc.	45.10 k	3.27 k shares	0.27	Common equity	Long	USA
Principal Government Money Market Fund	43.70 k	43.70 k shares	0.27	Short-term investment vehicle	Long	USA
XNCR Xencor, Inc.	43.65 k	2.31 k shares	0.27	Common equity	Long	USA
SILK Silk Road Medical Inc	42.97 k	1.59 k shares	0.26	Common equity	Long	USA
AORT Artivion, Inc.	42.43 k	1.65 k shares	0.26	Common equity	Long	USA
Prothena Corp. PLC	41.78 k	2.02 k shares	0.25	Common equity	Long	Ireland
NRIX Nurix Therapeutics, Inc.	41.57 k	1.99 k shares	0.25	Common equity	Long	USA
IRON Disc Medicine, Inc.	41.10 k	912.00 shares	0.25	Common equity	Long	USA
ARQT Arcutis Biotherapeutics, Inc.	40.90 k	4.40 k shares	0.25	Common equity	Long	USA
ATRC AtriCure, Inc.	40.62 k	1.78 k shares	0.25	Common equity	Long	USA
ELVN Enliven Therapeutics, Inc.	39.19 k	1.68 k shares	0.24	Common equity	Long	USA
FDMT 4D Molecular Therapeutics, Inc.	38.83 k	1.85 k shares	0.24	Common equity	Long	USA
BLFS BioLife Solutions, Inc.	38.60 k	1.80 k shares	0.23	Common equity	Long	USA
OCUL Ocular Therapeutix, Inc.	38.25 k	5.59 k shares	0.23	Common equity	Long	USA
TARS Tarsus Pharmaceuticals, Inc.	38.22 k	1.41 k shares	0.23	Common equity	Long	USA
LBPH Longboard Pharmaceuticals, Inc.	36.79 k	1.36 k shares	0.22	Common equity	Long	USA
TNGX Tango Therapeutics, Inc.	36.39 k	4.24 k shares	0.22	Common equity	Long	USA
MRVI Maravai LifeSciences Holdings, Inc.	36.19 k	5.05 k shares	0.22	Common equity	Long	USA
AVNS Avanos Medical, Inc.	36.08 k	1.81 k shares	0.22	Common equity	Long	USA
COGT Cogent Biosciences, Inc.	35.75 k	4.24 k shares	0.22	Common equity	Long	USA
Liquidia Corporation	34.96 k	2.91 k shares	0.21	Common equity	Long	USA
CDNA CareDx, Inc	34.41 k	2.22 k shares	0.21	Common equity	Long	USA
AUPH Aurinia Pharmaceuticals Inc.	33.59 k	5.88 k shares	0.20	Common equity	Long	Canada
TYRA Tyra Biosciences, Inc.	33.29 k	2.08 k shares	0.20	Common equity	Long	USA
RLAY Relay Therapeutics, Inc.	32.94 k	5.05 k shares	0.20	Common equity	Long	USA
HROW Harrow Health, Inc.	32.65 k	1.56 k shares	0.20	Common equity	Long	USA
SPRY ARS Pharmaceuticals, Inc.	31.91 k	3.75 k shares	0.19	Common equity	Long	USA
VRDN Viridian Therapeutics, Inc.	31.45 k	2.42 k shares	0.19	Common equity	Long	USA
CGEM Cullinan Oncology, Inc.	30.40 k	1.74 k shares	0.18	Common equity	Long	USA
Kiniksa Pharmaceuticals International PLC	30.04 k	1.61 k shares	0.18	Common equity	Long	UK
CTKB Cytek Biosciences, Inc.	28.82 k	5.16 k shares	0.18	Common equity	Long	USA
ETNB 89bio, Inc.	28.75 k	3.59 k shares	0.17	Common equity	Long	USA
HLVX HilleVax, Inc.	28.60 k	1.98 k shares	0.17	Common equity	Long	USA
ANAB AnaptysBio, Inc.	28.07 k	1.12 k shares	0.17	Common equity	Long	USA
KIDS OrthoPediatrics Corp.	27.70 k	963.00 shares	0.17	Common equity	Long	USA
PLSE Pulse Biosciences, Inc.	27.06 k	2.42 k shares	0.16	Common equity	Long	USA
SRDX Surmodics, Inc.	26.99 k	642.00 shares	0.16	Common equity	Long	USA
HUMA Humacyte, Inc.	26.74 k	5.57 k shares	0.16	Common equity	Long	USA
EOLS Evolus, Inc.	26.50 k	2.44 k shares	0.16	Common equity	Long	USA
TVTX Travere Therapeutics, Inc.	26.36 k	3.21 k shares	0.16	Common equity	Long	USA
Arcturus Therapeutics Holdings, Inc.	25.84 k	1.06 k shares	0.16	Common equity	Long	USA
CRGX CARGO Therapeutics, Inc. Common Stock	25.57 k	1.56 k shares	0.16	Common equity	Long	USA
NUVB Nuvation Bio Inc.	25.52 k	8.74 k shares	0.16	Common equity	Long	USA
PLRX Pliant Therapeutics, Inc.	25.51 k	2.37 k shares	0.16	Common equity	Long	USA
AVBP ArriVent BioPharma, Inc. Common Stock	25.23 k	1.36 k shares	0.15	Common equity	Long	USA
OLMA Olema Pharmaceuticals, Inc.	25.20 k	2.33 k shares	0.15	Common equity	Long	USA
PHAT Phathom Pharmaceuticals, Inc.	25.15 k	2.44 k shares	0.15	Common equity	Long	USA
SAGE Sage Therapeutics, Inc.	25.05 k	2.31 k shares	0.15	Common equity	Long	USA
EBS Emergent BioSolutions Inc.	24.78 k	3.63 k shares	0.15	Common equity	Long	USA
UroGen Pharma Ltd.	24.73 k	1.47 k shares	0.15	Common equity	Long	Israel
WaVe Life Sciences Ltd.	24.65 k	4.94 k shares	0.15	Common equity	Long	Singapore
ABUS Arbutus Biopharma Corporation	24.58 k	7.95 k shares	0.15	Common equity	Long	Canada
THRD Third Harmonic Bio, Inc.	24.48 k	1.88 k shares	0.15	Common equity	Long	USA
PRME Prime Medicine, Inc.	24.35 k	4.74 k shares	0.15	Common equity	Long	USA
SRRK Scholar Rock Holding Corporation	24.32 k	2.92 k shares	0.15	Common equity	Long	USA
Zymeworks Inc.	24.28 k	2.85 k shares	0.15	Common equity	Long	USA
MLYS Mineralys Therapeutics, Inc.	24.08 k	2.06 k shares	0.15	Common equity	Long	USA
REPL Replimune Group, Inc.	23.99 k	2.67 k shares	0.15	Common equity	Long	USA
HRTX Heron Therapeutics, Inc.	23.90 k	6.83 k shares	0.15	Common equity	Long	USA
ADPT Adaptive Biotechnologies Corporation	23.25 k	6.42 k shares	0.14	Common equity	Long	USA
ITOS iTeos Therapeutics, Inc.	23.21 k	1.56 k shares	0.14	Common equity	Long	USA
PEPG PepGen Inc.	22.81 k	1.43 k shares	0.14	Common equity	Long	USA
SVRA Savara Inc.	22.80 k	5.66 k shares	0.14	Common equity	Long	USA
SIGA SIGA Technologies, Inc.	22.63 k	2.98 k shares	0.14	Common equity	Long	USA
RGNX REGENXBIO Inc.	22.25 k	1.90 k shares	0.14	Common equity	Long	USA
ZIMV ZimVie Inc.	21.97 k	1.20 k shares	0.13	Common equity	Long	USA
FNA Paragon 28, Inc.	21.93 k	3.21 k shares	0.13	Common equity	Long	USA
SIBN SI-BONE, Inc.	21.88 k	1.69 k shares	0.13	Common equity	Long	USA
YMAB Y-mAbs Therapeutics, Inc.	21.61 k	1.79 k shares	0.13	Common equity	Long	USA
KALV KalVista Pharmaceuticals, Inc.	21.59 k	1.83 k shares	0.13	Common equity	Long	USA
OFIX Orthofix Medical Inc.	21.30 k	1.61 k shares	0.13	Common equity	Long	USA
SAVA Cassava Sciences, Inc.	21.06 k	1.71 k shares	0.13	Common equity	Long	USA
TRDA Entrada Therapeutics, Inc.	20.99 k	1.47 k shares	0.13	Common equity	Long	USA
CDMO Avid Bioservices, Inc.	20.45 k	2.86 k shares	0.12	Common equity	Long	USA
LRMR Larimar Therapeutics, Inc.	20.31 k	2.80 k shares	0.12	Common equity	Long	USA
ATXS Astria Therapeutics, Inc.	20.14 k	2.21 k shares	0.12	Common equity	Long	USA
TERN Terns Pharmaceuticals, Inc.	19.89 k	2.92 k shares	0.12	Common equity	Long	USA
QTRX Quanterix Corporation	19.76 k	1.50 k shares	0.12	Common equity	Long	USA
SCLX Scilex Holding Company	19.45 k	10.08 k shares	0.12	Common equity	Long	USA
LXEO Lexeo Therapeutics, Inc. Common Stock	19.30 k	1.20 k shares	0.12	Common equity	Long	USA
ORIC ORIC Pharmaceuticals, Inc.	18.69 k	2.64 k shares	0.11	Common equity	Long	USA
AGEN Agenus Inc.	18.66 k	1.11 k shares	0.11	Common equity	Long	USA
VYGR Voyager Therapeutics, Inc.	18.60 k	2.35 k shares	0.11	Common equity	Long	USA
Precigen, Inc.	18.54 k	11.73 k shares	0.11	Common equity	Long	USA
Theravance Biopharma, Inc.	18.42 k	2.17 k shares	0.11	Common equity	Long	Cayman Islands
ALEC Alector, Inc.	18.39 k	4.05 k shares	0.11	Common equity	Long	USA
MXCT MaxCyte, Inc.	18.32 k	4.67 k shares	0.11	Common equity	Long	USA
OABI OmniAb, Inc.	18.27 k	4.87 k shares	0.11	Common equity	Long	USA
SLRN Acelyrin, Inc.	17.91 k	4.06 k shares	0.11	Common equity	Long	USA
ERAS Erasca, Inc.	17.60 k	7.46 k shares	0.11	Common equity	Long	USA
LXRX Lexicon Pharmaceuticals, Inc.	17.41 k	10.36 k shares	0.11	Common equity	Long	USA
ANIK Anika Therapeutics, Inc.	17.40 k	687.00 shares	0.11	Common equity	Long	USA
AURA Aura Biosciences, Inc.	17.27 k	2.28 k shares	0.11	Common equity	Long	USA
CELC Celcuity Inc.	17.15 k	1.05 k shares	0.10	Common equity	Long	USA
NKTX Nkarta, Inc.	16.83 k	2.85 k shares	0.10	Common equity	Long	USA
EYPT EyePoint Pharmaceuticals, Inc.	16.74 k	1.92 k shares	0.10	Common equity	Long	USA
TMCI Treace Medical Concepts, Inc.	16.39 k	2.46 k shares	0.10	Common equity	Long	USA
ANNX Annexon, Inc.	16.31 k	3.33 k shares	0.10	Common equity	Long	USA
EDIT Editas Medicine, Inc.	16.02 k	3.43 k shares	0.10	Common equity	Long	USA
ALLO Allogene Therapeutics, Inc.	15.91 k	6.83 k shares	0.10	Common equity	Long	USA
AVXL Anavex Life Sciences Corp.	15.72 k	3.72 k shares	0.10	Common equity	Long	USA
LYEL Lyell Immunopharma, Inc.	15.64 k	10.79 k shares	0.10	Common equity	Long	USA
Xeris Pharmaceuticals Inc	15.57 k	6.92 k shares	0.09	Common equity	Long	USA
ALT Altimmune, Inc.	15.28 k	2.30 k shares	0.09	Common equity	Long	USA
CERS Cerus Corporation	15.26 k	8.67 k shares	0.09	Common equity	Long	USA
AXGN AxoGen, Inc.	14.90 k	2.06 k shares	0.09	Common equity	Long	USA
VERV Verve Therapeutics, Inc.	14.81 k	3.03 k shares	0.09	Common equity	Long	USA
OM Outset Medical, Inc.	14.77 k	3.84 k shares	0.09	Common equity	Long	USA
CABA Cabaletta Bio, Inc.	14.38 k	1.92 k shares	0.09	Common equity	Long	USA
NxStage Medical, Inc.	14.26 k	10.41 k shares	0.09	Common equity	Long	USA
OMER Omeros Corporation	14.23 k	3.50 k shares	0.09	Common equity	Long	USA