iShares Biotechnology ETF

Fund Profile

Fund profile

Tickers

IBB

Fund manager

iShares Russell Small/Mid-Cap Index Fund - Class A

Total assets

$6.93 bn

Liabilities

$470.05 mm

Net assets

$6.46 bn

Number of holdings

269.00

IBB stock data

1M 3M 6M 1Y

Top 200 of 269 Holdings

As of Dec 2024

Security	$Holding	Balance	% of Fund	Category	Position	Country
GILD Gilead Sciences, Inc.	554.12 mm	6.00 mm shares	8.57	Common equity	Long	USA
AMGN Amgen Inc.	511.74 mm	1.96 mm shares	7.92	Common equity	Long	USA
REGN Regeneron Pharmaceuticals, Inc.	492.56 mm	691.48 k shares	7.62	Common equity	Long	USA
VRTX Vertex Pharmaceuticals Incorporated	477.76 mm	1.19 mm shares	7.39	Common equity	Long	USA
BlackRock Cash Funds: Institutional, SL Agency Shares	465.81 mm	465.58 mm shares	7.21	Short-term investment vehicle	Long	USA
IQV IQVIA Holdings Inc.	230.88 mm	1.17 mm shares	3.57	Common equity	Long	USA
ALNY Alnylam Pharmaceuticals, Inc.	196.50 mm	835.06 k shares	3.04	Common equity	Long	USA
Argenx SE	188.09 mm	305.83 k shares	2.91	Common equity	Long	Netherlands
MTD Mettler-Toledo International Inc.	165.96 mm	135.62 k shares	2.57	Common equity	Long	USA
BIIB Biogen Inc.	144.41 mm	944.32 k shares	2.23	Common equity	Long	USA
WAT Waters Corporation	143.66 mm	387.25 k shares	2.22	Common equity	Long	USA
BNTX BioNTech SE	138.98 mm	1.22 mm shares	2.15	Common equity	Long	Germany
ILMN Illumina, Inc.	137.27 mm	1.03 mm shares	2.12	Common equity	Long	USA
NTRA Natera, Inc.	128.12 mm	809.35 k shares	1.98	Common equity	Long	USA
UTHR United Therapeutics Corporation	100.91 mm	286.00 k shares	1.56	Common equity	Long	USA
MRNA Moderna, Inc.	93.13 mm	2.24 mm shares	1.44	Common equity	Long	USA
ONC BeiGene, Ltd.	91.03 mm	492.83 k shares	1.41	Common equity	Long	Cayman Islands
NBIX Neurocrine Biosciences, Inc.	87.79 mm	643.12 k shares	1.36	Common equity	Long	USA
INCY Incyte Corporation	85.45 mm	1.24 mm shares	1.32	Common equity	Long	USA
BMRN BioMarin Pharmaceutical Inc.	80.74 mm	1.23 mm shares	1.25	Common equity	Long	USA
INSM Insmed Incorporated	78.60 mm	1.14 mm shares	1.22	Common equity	Long	USA
TECH Bio-Techne Corporation	73.92 mm	1.03 mm shares	1.14	Common equity	Long	USA
Genmab A/S	70.93 mm	3.40 mm shares	1.10	Common equity	Long	Denmark
SRPT Sarepta Therapeutics, Inc.	70.57 mm	580.39 k shares	1.09	Common equity	Long	USA
PCVX Vaxcyte, Inc.	64.22 mm	784.54 k shares	0.99	Common equity	Long	USA
CRL Charles River Laboratories International, Inc.	60.96 mm	330.21 k shares	0.94	Common equity	Long	USA
EXEL Exelixis, Inc.	60.52 mm	1.82 mm shares	0.94	Common equity	Long	USA
MEDP Medpace Holdings, Inc.	55.31 mm	166.49 k shares	0.86	Common equity	Long	USA
ITCI Intra-Cellular Therapies, Inc.	54.01 mm	646.72 k shares	0.84	Common equity	Long	USA
RGEN Repligen Corporation	48.95 mm	340.05 k shares	0.76	Common equity	Long	USA
ASND Ascendis Pharma A/S	42.24 mm	306.82 k shares	0.65	Common equity	Long	Denmark
RVMD Revolution Medicines, Inc.	40.26 mm	920.37 k shares	0.62	Common equity	Long	USA
BRKR Bruker Corporation	39.38 mm	671.85 k shares	0.61	Common equity	Long	USA
HALO Halozyme Therapeutics, Inc.	39.27 mm	821.47 k shares	0.61	Common equity	Long	USA
MDGL Madrigal Pharmaceuticals, Inc.	37.02 mm	119.96 k shares	0.57	Common equity	Long	USA
BPMC Blueprint Medicines Corporation	35.09 mm	402.28 k shares	0.54	Common equity	Long	USA
CYTK Cytokinetics, Incorporated	34.88 mm	741.48 k shares	0.54	Common equity	Long	USA
IONS Ionis Pharmaceuticals, Inc.	33.21 mm	950.06 k shares	0.51	Common equity	Long	USA
LEGN Legend Biotech Corporation	30.56 mm	939.05 k shares	0.47	Common equity	Long	Cayman Islands
Alkermes plc	29.81 mm	1.04 mm shares	0.46	Common equity	Long	Ireland
Roivant Sciences Ltd.	29.14 mm	2.46 mm shares	0.45	Common equity	Long	Bermuda
CRNX Crinetics Pharmaceuticals, Inc.	28.95 mm	566.12 k shares	0.45	Common equity	Long	USA
BBIO BridgeBio Pharma, Inc.	26.44 mm	963.61 k shares	0.41	Common equity	Long	USA
ADMA ADMA Biologics, Inc.	25.59 mm	1.49 mm shares	0.40	Common equity	Long	USA
KRYS Krystal Biotech, Inc.	24.88 mm	158.81 k shares	0.38	Common equity	Long	USA
RARE Ultragenyx Pharmaceutical Inc.	22.90 mm	544.24 k shares	0.35	Common equity	Long	USA
PTCT PTC Therapeutics, Inc.	21.98 mm	486.84 k shares	0.34	Common equity	Long	USA
AXSM Axsome Therapeutics, Inc.	21.85 mm	258.28 k shares	0.34	Common equity	Long	USA
Biohaven Ltd.	21.63 mm	579.08 k shares	0.33	Common equity	Long	Virgin Islands (British)
NUVL Nuvalent, Inc.	21.21 mm	270.90 k shares	0.33	Common equity	Long	USA
APLS Apellis Pharmaceuticals, Inc.	21.16 mm	663.01 k shares	0.33	Common equity	Long	USA
CRISPR Therapeutics AG	20.94 mm	532.13 k shares	0.32	Common equity	Long	Switzerland
RNA Avidity Biosciences, Inc.	20.58 mm	707.62 k shares	0.32	Common equity	Long	USA
ACLX Arcellx, Inc.	20.40 mm	266.04 k shares	0.32	Common equity	Long	USA
VCYT Veracyte, Inc.	19.76 mm	498.90 k shares	0.31	Common equity	Long	USA
ACAD ACADIA Pharmaceuticals Inc.	19.71 mm	1.07 mm shares	0.30	Common equity	Long	USA
RYTM Rhythm Pharmaceuticals, Inc.	19.63 mm	350.60 k shares	0.30	Common equity	Long	USA
SRRK Scholar Rock Holding Corporation	19.50 mm	451.23 k shares	0.30	Common equity	Long	USA
Novocure Ltd.	18.96 mm	636.36 k shares	0.29	Common equity	Long	Jersey
XENE Xenon Pharmaceuticals Inc.	18.78 mm	479.11 k shares	0.29	Common equity	Long	Canada
FOLD Amicus Therapeutics, Inc.	17.94 mm	1.90 mm shares	0.28	Common equity	Long	USA
VCEL Vericel Corporation	17.56 mm	319.78 k shares	0.27	Common equity	Long	USA
TWST Twist Bioscience Corporation	17.11 mm	368.29 k shares	0.26	Common equity	Long	USA
DNLI Denali Therapeutics Inc.	16.57 mm	813.11 k shares	0.26	Common equity	Long	USA
VRNA Verona Pharma plc	16.39 mm	352.82 k shares	0.25	Common equity	Long	UK
Merus NV	16.05 mm	381.69 k shares	0.25	Common equity	Long	Netherlands
SWTX SpringWorks Therapeutics, Inc.	15.49 mm	428.65 k shares	0.24	Common equity	Long	USA
JANX Janux Therapeutics, Inc.	14.88 mm	277.98 k shares	0.23	Common equity	Long	USA
Zai Lab Ltd.	14.55 mm	555.62 k shares	0.23	Common equity	Long	Cayman Islands
KYMR Kymera Therapeutics, Inc.	14.38 mm	357.39 k shares	0.22	Common equity	Long	USA
ARWR Arrowhead Pharmaceuticals, Inc.	14.23 mm	756.70 k shares	0.22	Common equity	Long	USA
PTGX Protagonist Therapeutics, Inc.	14.16 mm	366.78 k shares	0.22	Common equity	Long	USA
VERA Vera Therapeutics, Inc.	13.55 mm	320.32 k shares	0.21	Common equity	Long	USA
RXRX Recursion Pharmaceuticals, Inc.	13.32 mm	1.97 mm shares	0.21	Common equity	Long	USA
GERN Geron Corporation	13.02 mm	3.68 mm shares	0.20	Common equity	Long	USA
IDYA IDEAYA Biosciences, Inc.	12.93 mm	503.06 k shares	0.20	Common equity	Long	USA
SMMT Summit Therapeutics Inc.	12.04 mm	674.65 k shares	0.19	Common equity	Long	USA
IOVA Iovance Biotherapeutics, Inc.	11.91 mm	1.61 mm shares	0.18	Common equity	Long	USA
DYN Dyne Therapeutics, Inc.	11.82 mm	501.67 k shares	0.18	Common equity	Long	USA
TARS Tarsus Pharmaceuticals, Inc.	11.81 mm	213.34 k shares	0.18	Common equity	Long	USA
AGIO Agios Pharmaceuticals, Inc.	11.80 mm	359.22 k shares	0.18	Common equity	Long	USA
BEAM Beam Therapeutics Inc.	11.74 mm	473.44 k shares	0.18	Common equity	Long	USA
MESO Mesoblast Limited	11.65 mm	588.51 k shares	0.18	Common equity	Long	Australia
MNKD MannKind Corporation	11.20 mm	1.74 mm shares	0.17	Common equity	Long	USA
Tempus AI, Inc.	10.99 mm	325.47 k shares	0.17	Common equity	Long	USA
DVAX Dynavax Technologies Corporation	10.89 mm	852.92 k shares	0.17	Common equity	Long	USA
EWTX Edgewise Therapeutics, Inc.	10.86 mm	406.64 k shares	0.17	Common equity	Long	USA
FTRE Fortrea Holdings Inc.	10.81 mm	579.88 k shares	0.17	Common equity	Long	USA
APGE Apogee Therapeutics, Inc.	10.77 mm	237.80 k shares	0.17	Common equity	Long	USA
AKRO Akero Therapeutics, Inc.	10.65 mm	382.97 k shares	0.16	Common equity	Long	USA
MIRM Mirum Pharmaceuticals, Inc.	10.36 mm	250.49 k shares	0.16	Common equity	Long	USA
IMVT Immunovant, Inc.	10.09 mm	407.46 k shares	0.16	Common equity	Long	USA
XNCR Xencor, Inc.	9.92 mm	431.83 k shares	0.15	Common equity	Long	USA
GRFS Grifols, S.A.	9.91 mm	1.33 mm shares	0.15	Common equity	Long	Spain
TVTX Travere Therapeutics, Inc.	9.73 mm	558.47 k shares	0.15	Common equity	Long	USA
WaVe Life Sciences Ltd.	9.58 mm	774.60 k shares	0.15	Common equity	Long	Singapore
Alvotech SA	9.41 mm	711.06 k shares	0.15	Common equity	Long	Luxembourg
TXG 10x Genomics, Inc.	9.40 mm	654.40 k shares	0.15	Common equity	Long	USA
ARQT Arcutis Biotherapeutics, Inc.	9.34 mm	670.68 k shares	0.14	Common equity	Long	USA
BCRX BioCryst Pharmaceuticals, Inc.	9.26 mm	1.23 mm shares	0.14	Common equity	Long	USA
GLPG Galapagos NV	9.09 mm	330.62 k shares	0.14	Common equity	Long	Belgium
PRAX Praxis Precision Medicines, Inc.	8.64 mm	112.26 k shares	0.13	Common equity	Long	USA
NRIX Nurix Therapeutics, Inc.	8.46 mm	448.87 k shares	0.13	Common equity	Long	USA
NVAX Novavax, Inc.	8.02 mm	996.98 k shares	0.12	Common equity	Long	USA
BlackRock Cash Funds: Treasury, SL Agency Shares	7.87 mm	7.87 mm shares	0.12	Short-term investment vehicle	Long	USA
MYGN Myriad Genetics, Inc.	7.83 mm	570.81 k shares	0.12	Common equity	Long	USA
CGON CG Oncology, Inc. Common stock	7.70 mm	268.35 k shares	0.12	Common equity	Long	USA
CNTA Centessa Pharmaceuticals plc	7.66 mm	457.38 k shares	0.12	Common equity	Long	UK
NTLA Intellia Therapeutics, Inc.	7.60 mm	652.18 k shares	0.12	Common equity	Long	USA
GPCR Structure Therapeutics Inc.	7.53 mm	277.77 k shares	0.12	Common equity	Long	Cayman Islands
AUPH Aurinia Pharmaceuticals Inc.	7.53 mm	838.27 k shares	0.12	Common equity	Long	Canada
ARVN Arvinas, Inc.	7.43 mm	387.78 k shares	0.12	Common equity	Long	USA
SYRE Spyre Therapeutics, Inc.	7.38 mm	317.20 k shares	0.11	Common equity	Long	USA
IMCR Immunocore Holdings plc	7.36 mm	249.49 k shares	0.11	Common equity	Long	UK
Newamsterdam Pharma Co. NV	7.19 mm	279.61 k shares	0.11	Common equity	Long	Netherlands
Stevanato Group SpA	7.02 mm	322.35 k shares	0.11	Common equity	Long	Italy
CDNA CareDx, Inc	7.00 mm	326.79 k shares	0.11	Common equity	Long	USA
SNDX Syndax Pharmaceuticals, Inc.	6.98 mm	528.15 k shares	0.11	Common equity	Long	USA
RCKT Rocket Pharmaceuticals, Inc.	6.80 mm	540.88 k shares	0.11	Common equity	Long	USA
IRON Disc Medicine, Inc.	6.45 mm	101.78 k shares	0.10	Common equity	Long	USA
Zymeworks Inc.	6.40 mm	437.13 k shares	0.10	Common equity	Long	USA
EVO Evotec SE	5.92 mm	1.42 mm shares	0.09	Common equity	Long	Germany
AVXL Anavex Life Sciences Corp.	5.74 mm	534.92 k shares	0.09	Common equity	Long	USA
ETNB 89bio, Inc.	5.73 mm	732.46 k shares	0.09	Common equity	Long	USA
DAWN Day One Biopharmaceuticals, Inc.	5.65 mm	445.68 k shares	0.09	Common equity	Long	USA
ADPT Adaptive Biotechnologies Corporation	5.58 mm	929.95 k shares	0.09	Common equity	Long	USA
CTKB Cytek Biosciences, Inc.	4.95 mm	762.50 k shares	0.08	Common equity	Long	USA
uniQure NV	4.91 mm	278.03 k shares	0.08	Common equity	Long	Netherlands
CSTL Castle Biosciences, Inc.	4.76 mm	178.50 k shares	0.07	Common equity	Long	USA
REPL Replimune Group, Inc.	4.73 mm	390.55 k shares	0.07	Common equity	Long	USA
RCUS Arcus Biosciences, Inc.	4.67 mm	313.45 k shares	0.07	Common equity	Long	USA
PLRX Pliant Therapeutics, Inc.	4.61 mm	350.22 k shares	0.07	Common equity	Long	USA
COGT Cogent Biosciences, Inc.	4.52 mm	579.39 k shares	0.07	Common equity	Long	USA
IRWD Ironwood Pharmaceuticals, Inc.	4.50 mm	1.01 mm shares	0.07	Common equity	Long	USA
ELVN Enliven Therapeutics, Inc.	4.46 mm	198.00 k shares	0.07	Common equity	Long	USA
ABCL AbCellera Biologics Inc.	4.24 mm	1.45 mm shares	0.07	Common equity	Long	Canada
PSTX Poseida Therapeutics, Inc.	4.21 mm	438.36 k shares	0.07	Common equity	Long	USA
LENZ LENZ Therapeutics, Inc.	4.21 mm	145.72 k shares	0.07	Common equity	Long	USA
VIR Vir Biotechnology, Inc.	4.18 mm	568.84 k shares	0.06	Common equity	Long	USA
MRVI Maravai LifeSciences Holdings, Inc.	4.17 mm	765.80 k shares	0.06	Common equity	Long	USA
LAB Standard BioTools Inc.	4.11 mm	2.35 mm shares	0.06	Common equity	Long	USA
Prothena Corp. plc	4.04 mm	291.84 k shares	0.06	Common equity	Long	Ireland
NUVB Nuvation Bio Inc.	3.95 mm	1.49 mm shares	0.06	Common equity	Long	USA
ORKA Oruka Therapeutics Inc.	3.80 mm	196.19 k shares	0.06	Common equity	Long	USA
NMRA Neumora Therapeutics, Inc. Common Stock	3.75 mm	353.97 k shares	0.06	Common equity	Long	USA
KURA Kura Oncology, Inc.	3.70 mm	425.10 k shares	0.06	Common equity	Long	USA
SPRY ARS Pharmaceuticals, Inc.	3.53 mm	334.44 k shares	0.05	Common equity	Long	USA
HUMA Humacyte, Inc.	3.41 mm	675.70 k shares	0.05	Common equity	Long	USA
ArriVent Biopharma, Inc.	3.38 mm	126.72 k shares	0.05	Common equity	Long	USA
ALT Altimmune, Inc.	3.31 mm	459.55 k shares	0.05	Common equity	Long	USA
GRAL GRAIL, Inc.	3.31 mm	185.16 k shares	0.05	Common equity	Long	USA
RLAY Relay Therapeutics, Inc.	3.27 mm	794.38 k shares	0.05	Common equity	Long	USA
BCYC Bicycle Therapeutics plc	3.24 mm	231.64 k shares	0.05	Common equity	Long	UK
EBS Emergent BioSolutions Inc.	3.24 mm	338.94 k shares	0.05	Common equity	Long	USA
CRMD CorMedix Inc.	3.15 mm	389.37 k shares	0.05	Common equity	Long	USA
ABUS Arbutus Biopharma Corporation	3.14 mm	959.22 k shares	0.05	Common equity	Long	Canada
NxStage Medical, Inc.	3.13 mm	1.71 mm shares	0.05	Common equity	Long	USA
KROS Keros Therapeutics, Inc.	3.12 mm	196.80 k shares	0.05	Common equity	Long	USA
OPK OPKO Health, Inc.	3.05 mm	2.07 mm shares	0.05	Common equity	Long	USA
CRGX CARGO Therapeutics, Inc. Common Stock	3.01 mm	208.67 k shares	0.05	Common equity	Long	USA
ANNX Annexon, Inc.	2.99 mm	582.00 k shares	0.05	Common equity	Long	USA
STOK Stoke Therapeutics, Inc.	2.96 mm	267.96 k shares	0.05	Common equity	Long	USA
CGEM Cullinan Oncology, Inc.	2.94 mm	241.44 k shares	0.05	Common equity	Long	USA
ZVRA Zevra Therapeutics, Inc.	2.88 mm	345.78 k shares	0.04	Common equity	Long	USA
AUTL Autolus Therapeutics plc	2.85 mm	1.21 mm shares	0.04	Common equity	Long	UK
ATXS Astria Therapeutics, Inc.	2.81 mm	314.40 k shares	0.04	Common equity	Long	USA
Theravance Biopharma, Inc.	2.78 mm	295.25 k shares	0.04	Common equity	Long	Cayman Islands
Arcturus Therapeutics Holdings, Inc.	2.72 mm	160.13 k shares	0.04	Common equity	Long	USA
ERAS Erasca, Inc.	2.67 mm	1.06 mm shares	0.04	Common equity	Long	USA
IBRX ImmunityBio, Inc.	2.66 mm	1.04 mm shares	0.04	Common equity	Long	USA
MXCT MaxCyte, Inc.	2.64 mm	634.18 k shares	0.04	Common equity	Long	USA
TYRA Tyra Biosciences, Inc.	2.56 mm	184.53 k shares	0.04	Common equity	Long	USA
UroGen Pharma Ltd.	2.53 mm	237.92 k shares	0.04	Common equity	Long	Israel
QTRX Quanterix Corporation	2.48 mm	233.55 k shares	0.04	Common equity	Long	USA
CDXS Codexis, Inc.	2.45 mm	513.79 k shares	0.04	Common equity	Long	USA
TRDA Entrada Therapeutics, Inc.	2.44 mm	141.32 k shares	0.04	Common equity	Long	USA
FLGT Fulgent Genetics, Inc.	2.40 mm	129.77 k shares	0.04	Common equity	Long	USA
TECX Tectonic Therapeutic Inc	2.34 mm	50.72 k shares	0.04	Common equity	Long	USA
SPOT Spotify Technology S.A.	2.32 mm	236.61 k shares	0.04	Common equity	Long	USA
VERV Verve Therapeutics, Inc.	2.32 mm	411.08 k shares	0.04	Common equity	Long	USA
AURA Aura Biosciences, Inc.	2.30 mm	279.33 k shares	0.04	Common equity	Long	USA
RGNX REGENXBIO Inc.	2.26 mm	292.15 k shares	0.03	Common equity	Long	USA
TERN Terns Pharmaceuticals, Inc.	2.25 mm	406.00 k shares	0.03	Common equity	Long	USA
ANAB AnaptysBio, Inc.	2.24 mm	169.25 k shares	0.03	Common equity	Long	USA
ORIC ORIC Pharmaceuticals, Inc.	2.22 mm	274.53 k shares	0.03	Common equity	Long	USA
GLUE Monte Rosa Therapeutics, Inc.	2.09 mm	300.89 k shares	0.03	Common equity	Long	USA
MeiraGTx Holdings plc	2.08 mm	342.32 k shares	0.03	Common equity	Long	Cayman Islands
CureVac NV	2.08 mm	610.06 k shares	0.03	Common equity	Long	Netherlands
RAPP Rapport Therapeutics, Inc. Common Stock	2.02 mm	113.85 k shares	0.03	Common equity	Long	USA
ALLO Allogene Therapeutics, Inc.	2.00 mm	938.40 k shares	0.03	Common equity	Long	USA
TRML Tourmaline Bio, Inc.	1.99 mm	97.98 k shares	0.03	Common equity	Long	USA
SAGE Sage Therapeutics, Inc.	1.94 mm	357.27 k shares	0.03	Common equity	Long	USA
MLYS Mineralys Therapeutics, Inc.	1.90 mm	154.21 k shares	0.03	Common equity	Long	USA
YMAB Y-mAbs Therapeutics, Inc.	1.90 mm	242.23 k shares	0.03	Common equity	Long	USA
RVNC Revance Therapeutics, Inc.	1.90 mm	623.53 k shares	0.03	Common equity	Long	USA
RIGL Rigel Pharmaceuticals, Inc.	1.89 mm	112.49 k shares	0.03	Common equity	Long	USA
OLMA Olema Pharmaceuticals, Inc.	1.88 mm	323.02 k shares	0.03	Common equity	Long	USA
PHAT Phathom Pharmaceuticals, Inc.	1.88 mm	231.38 k shares	0.03	Common equity	Long	USA
KalVista Pharmaceuticals, Inc.	1.78 mm	210.67 k shares	0.03	Common equity	Long	USA
SVRA Savara Inc.	1.75 mm	569.93 k shares	0.03	Common equity	Long	USA